ÖZLEM COŞKUN, Serap ÜÇLER, Levent Ertuğrul İNAN, Ruhsen ÖCAL

A case report: indomethacin resistance hemicrania continua or a new entity?

Hemicrania continua (HC) nadir primer başağrısıdır. Bazı otonomik bulgularla birliktedir (konjunktival yaşarma, pitoz, gözkapağı ödemi, lakrimasyon, nazal konjesyon, rinore gibi). HC tanısı için indometazin tedavisine yanıt zorunlu tanı kriteridir. Bununla birlikte literatürde indometazine yanıt vermeyen olgular bildirilmiştir. Bu yazıda, indometazin yanıtı olmayan ancak pregabalin tedavisine yanıt veren bir olgu sunuldu. Pregabalin indometazine dirençli HC başağrısında bazı hastalar için etkili bir tedavi alternatifi olabilir.

Olgu sunumu: İndometazine dirençli hemicrania continua mı yoksa yeni bir başağrısı mı?

Hemicrania continua (HC) is a rare primary headache disorder. It presents some autonomic features (including conjunctival injection, ptosis, eyelid edema, lacrimation, nasal congestion, and rhinorrhea). Response to indomethacin treatment is the mandatory criteria for the diagnosis of HC. However, previously reported literature indicates that there are some reported cases that did not respond to indomethacin. In this case report, we present a patient who had indomethacin resistance with an associated pregabalin response. Pregabalin may be an effective treatment for hemicrania continua in some patients with indomethacin resistance.

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