Oral Ve Maksillofasial Cerrahide Bifosfonatlar Ve Bifosfonatla İlişkili Çene Osteonekrozu Tedavisinde Yeni Yaklaşımlar

Bifosfonatların; osteoporoz ve malign tümör tedavisinde kullanılmasıyla, günümüzde çene osteonekrozunun görülme sıklığını artmıştır. Bu nedenle, oral maksillofasial cerrahlar bifosfonatlar ile çene osteonekrozunun ilişkisini ve çene osteonekrozunun tedavisini araştırmaya başlamışlardır. Bu derlemede bifosfonatların etki mekanizması, kullanım alanları ve bifosfonata bağlı oluşan osteonekrozların tedavisinde uygulanan yeni tedavi protokolleri hakkında bilgi verilmesi amaçlanmıştır

Bisphosphonates And New Treatment Approachs of Bisphosphonate Related Osteonecrosis of the Jaws İn Oral And Maxillofacial Surgery

The use of biphosphonates for the treatment of osteoporosis and malignant tumors has caused an increase in the incident of osteonecrosis of the jaw recently. Therefore, oral maxillofacial surgeons have begun to investigate the relationship of between bisphosphonates and jaw osteonecrosis, treatment of jaw osteonecrosis. The purpose of this review is giving information about the mechanism of action of bisphosphonates, their use and the new treatment approachs of bisphosphonate-related osteonecrosis

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