ABSTRACTIn this case, vaginal leiomyosarcoma subsequent to pyometra is described in a 10-year old Labrador Retriever bitch. Bloody, malodorous discharge related to pyometra was present from the vagina for 4 months. Ovariohysterectomy recommended but the owner refused the operation. Three weeks after the first examination a rapidly growing mass and a bulge were noticed in the vagina. The dog underwent ovariohysterectomy and a biopsy was taken from the mass at the vagina during this surgery and submitted to pathology laboratory. It was diagnosed as leiomyosarcoma in histopathological and immunohistochemical examinations. After the mass extirpated surgically the recurrence was occurred in one and a half months later. The bitch's general condition deteriorated rapidly and she died. Because of the late arrival of the patient to our clinic and in order to the request of the owner, treatment protocols could not be able to applied properly so the case was failed. The aim of this case is to transfer the surgical approaches to these kinds of reproductive pathologies to the literature. It is concluded that these kinds of pathologies should be treated immediately.Key Words: Bitch, leiomyosarcoma, vagina, pyometra ÖZETBİR DİŞİ LABRADOR KÖPEKTE PYOMETRAYI TAKİBEN GÖRÜLEN VAGİNAL LEİOMYOSARKOMABu olguda 10 yaşlı Labrador dişi bir köpekte pyometrayı takiben görülen vaginal leiomyosarkoma anlatıldı. Köpekte 4 aydır devam eden pyometraya bağlı kanlı, pis kokulu vaginal akıntı vardı. Köpeğe ovariohisterektomi önerildi fakat hasta sahibi bu öneriyi reddetti. İlk muayeneden 3 hafta sonra hızlıca büyüyen, çıkıntı yapan bir kitle vaginada fark edildi. Köpeğe ovariohisterektomi yapıldı ve bu esnada vaginadaki kitleden de biyopsi alınarak patoloji laboratuarına yollandı. Histopatolojik ve immunohistokimyasal değerlendirme sonucunda kitle leiomyosarkoma olarak saptandı. Kitlenin ameliyatla uzaklaştırılmasından 1,5 ay sonra nüks gözlendi. Köpeğin genel durumu hızlıca kötüledi. Köpeğin kliniğimize geç getirilmesinden ve hasta sahibinin isteği doğrultusunda, tedavi protokollerinin düzenli olarak uygulanamamasından dolayı köpeği kaybettik. Bu olgunun amacı bu tarz reprodüktif patolojilerin cerrahi yaklaşımlarının yazına aktarılmasıdır. Sonuç olarak, bu tarz patolojilerin hızlıca tedavi edilmesi gerekliliği saptandı.Anahtar Kelimeler: Dişi köpek, leiomyosarkoma, vagina, pyometra

In this case, vaginal leiomyosarcoma subsequent to pyometra is described in a 10-year old Labrador Retriever bitch. Bloody, malodorous discharge related to pyometra was present from the vagina for 4 months. Ovariohysterectomy recommended but the owner refused the operation. Three weeks after the first examination a rapidly growing mass and a bulge were noticed in the vagina. The dog underwent ovariohysterectomy and a biopsy was taken from the mass at the vagina during this surgery and submitted to pathology laboratory. It was diagnosed as leiomyosarcoma in histopathological and immunohistochemical examinations. After the mass extirpated surgically the recurrence was occurred in one and a half months later. The bitch’s general condition deteriorated rapidly and she died. Because of the late arrival of the patient to our clinic and in order to the request of the owner, treatment protocols could not be able to applied properly so the case was failed. The aim of this case is to transfer the surgical approaches to these kinds of reproductive pathologies to the literature. It is concluded that these kinds of pathologies should be treated immediately.