Cartilage repair strategies in the knee: A survey of Turkish surgeons

Objectives: The purpose of this study was to analyze the trends in cartilage repair strategies amongTurkish orthopedic surgeons for isolated focal (osteo)chondral lesions of the knee joint.Materials and methods: A web-based survey of 21 questions consisting of surgical indications, techniquesand time to return to sports was developed to investigate the preferences of members of the TOTBID andthe TUSYAD.Results: A total of 147 surgeons answered the questionnaire.70% of the respondents were TUSYADmembers. 82% of respondents had at leastŞve years experience in arthroscopy. Half of the surgeonsindicated that patient age of 50 was the upper limit for cartilage repair. Irrespective of activity level,microfracture (60e67%) was the most frequently used technique for lesions smaller 2.5 cm2. In lesionslarger than 4 cm2, MACI was the most commonly advocated procedure (67%). In patients with highactivity levels, mosaicplasty was theŞrst choice (69%) for lesions between 2.5 and 4 cm2in size, followedby MACI (27%).Conclusion: Patient age, activity level, BMI and lesion size were important determinants for the choice oftreatment of isolated chondral lesions in the knee. These results reflect the choices of experienced kneesurgeons in the country. Although not widely performed in Turkey and has limited reimbursement by thehealth care system, theŞrst choice for defects over 4 cm2was second generation ACI. Third party payers& health reimbursement authorities should take into account that large defects require methods whichare relatively expensive and need high technology. Cross-sectional survey, Level II.© 2016 Turkish Association of Orthopaedics and Traumatology. Publishing services by Elsevier B.V. This isan open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Farr J, Cole BJ, Dhawan A, Kercher J, Sherman S. Clinical cartilage restoration: evolution and overview. Clin Orthop Relat Res. 2011;469:2696e2705.

Buckwalter JA. Evaluating methods for restoring cartilaginous articular sur- faces. Clin Orthop Relat Res. 1999;367S:S224eS238.

Brittberg M, Winalski CS. Evaluation of cartilage injuries and repair. J Bone Jt Surg Am. 2003;85-A(Suppl. 2):58e69.

Jakobsen RB, Engebretsen L, Slauterbeck JR. An analysis of the quality of cartilage repair studies. J Bone Jt Surg Am. 2005;87:2232e2239.

Knutsen G, Drogset JO, Engebretsen L, et al. A randomized trial comparing autologous chondrocyte implantation with microfracture:Şndings at Şve years. J Bone Jt Surg Am. 2007;89:2105e2112.

Knutsen G, Engebretsen L, Ludvigsen TC, et al. Autologous chondrocyte im- plantation compared with microfracture in the knee: a randomized trial. J Bone Jt Surg Am. 2004;86-A:455e464.

Benthien JP, Schwaninger M, Behrens P. We do not have evidence based methods for the treatment of cartilage defects in the knee. Knee Surg Sports Traumatol Arthrosc. 2011;19(4):543e552.

Theodoropoulos J, Dwyer T, Whelan D, Marks P, Hurtig M, Sharma P. Micro- fracture for knee chondral defects: a survey of surgical practice among Cana- dian orthopedic surgeons. Knee Surg Sports Traumatol Arthrosc. 2012;20: e2437.

Jüni P, Reichenbach S, Trelle S, et al. EfŞcacy and safety of intra-articular hylan or hyaluronic acids for osteoarthritis of the knee: a randomized controlled trial. Arthritis Rheum. 2007;56(11):3610e3619, 9.

Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroityn sulfate, and the two in cambination for painful knee osteoarthritis N. Engl J Med. 2006;354(8): e808.

Bellamy N, Campbell J, Robinson V, Gee T, Bourne R, Wells G. Intra-articular corticosteroid for treatment of osteoarthritis of the knee. Cochrane Database Syst Rev. 2006;19(2):CD005328. submitted for publication.

Zaffagnini S, Filardo G, Kon E, et al. The treatment of large degenerative defects. In: Brittberg M, Imhoff A, Madry H, Mandelbaum M, eds. Cartilage Repair. Current Concepts. 2010:89e98.

Bekkers JE, Inklaar M, Saris DB. Treatment selection in articular cartilage lesions of the knee: a systematic review. Am J Sports Med. 2009;37(Suppl. 1): Se155S.

de Windt TS, Bekkers JE, Creemers LB, Dhert WJ, Saris DB. Patient proŞling in cartilage regeneration: prognostic factors determining success of treatment for cartilage defects. Am J Sports Med. 2009;37(Suppl. 1):58Se62S.

Harris JD, Brophy RH, Siston RA, Flanigan DC. Treatment of chondral defects in the athlete's knee. Arthroscopy. 2010;26:841e852.

Asik M, Ciftci F, Sen C, Erdil M, Atalar A. The microfracture technique for the treatment of full-thickness articular cartilage lesions of the knee: midterm results. Arthroscopy. 2008;24:1214e1220.

Williams 3rd RJ, Harnly HW. Microfracture: indications, technique, and results. Instr Course Lect. 2007;56:419e428.

Gudas R, Kalesinskas RJ, Kimtys V, et al. A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus micro- fracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthroscopy. 2005;21(9):1066e1075.

Kreuz PC, Steinwachs MR, Erggelet C, et al. Results after microfracture of full- thickness chondral defects in different compartments in the knee. Osteoarthr Cartil. 2006;14:1119e1125.

Mithoefer K, Williams 3rd RJ, Warren RF, et al. The microfracture technique for the treatment of articular cartilage lesions in the knee: a prospective cohort study. J Bone Jt Surg Am. 2005;87:1911e1920.

Steadman JR, Rodkey WG, Rodrigo JJ. Microfracture: surgical technique and rehabilitation to treat chondral defects. Clin Orthop Relat Res. 2001;391(Suppl.): S362eS369.

Kon E, Filardo G, Berruto M, et al. Articular cartilage treatment in high-level male soccer players: a prospective comparative study of arthroscopic second-generation autologous chondrocyte implantation versus microfracture. Am J Med. 2011;39(12):2549e2557.

Steadman JR, Briggs KK, Rodrigo JJ, Kocher MS, Gill TJ, Rodkey WG. Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy. 2003;19:477e484.

Saris DB, Vanlauwe J, Victor J, et al. Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med. 2009;37(Suppl. 1):10Se19S.

Mithoefer K, McAdams T, Williams RJ, Kreuz PC, Mandelbaum BR. Clinical ef- Şcacy of the microfracture technique for articular cartilage repair in the knee: an evidence-based systematic analysis. Am J Sports Med. 2009;37(10): e2063.

Mithoefer K, Hambly K, Della Villa S, Silvers H, Mandelbaum BR. Return to sports participation after articular cartilage repair in the knee: scientiŞc evi- dence. Am J Sports Med. 2009;37(Suppl. 1):167Se176S.

Krych AJ, Harnly HW, Rodeo SA, Williams 3rd RJ. Activity levels are higher after osteochondral autograft transfer mosaicplasty than after microfracture for articular cartilage defects of the knee: a retrospective comparative study. J Bone Jt Surg Am. 2012;94(11):971e978.

Matricali GA, Dereymaeker GP, Luyten FP. Donor site morbidity after articular cartilage repair procedures : a review. Acta Orthop Belg. 2010;76(5):669e674.

Krishnan SP, Skinner JA, Bartlett W, et al. Who is the ideal candidate for autologous chondrocyte implantation? J Bone Jt Surg Br. 2006;88:61e64.

Saris DB, Vanlauwe J, Victor J, et al. Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture. Am J Sports Med. 2008;36(2):235e246.

Williams JM, Moran M, Thonar EJ, Salter RB. Continuous passive motion stimulates repair of rabbit knee articular cartilage after matrix proteoglycan loss. Clin Orthop Relat Res. 1994;304:252e262.

Hangody L, Dobos J, Balo E, Panics G, Hangody LR, Berkes I. Clinical experiences with autologous osteochondral mosaicplasty in an athletic population: a 17- year prospective multicenter study. Am J Sports Med. 2010;38(6):1125e1133.
Acta Orthopaedica et Traumatologica Turcica-Cover
  • ISSN: 1017-995X
  • Başlangıç: 2015
  • Yayıncı: Türk Ortopedi ve Travmatoloji Derneği
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