Yıldız GÜNEY, Meltem Nalça ANDRIEU, Ayşe HİÇSÖZMEZ, Caner AKTAŞ, Cengiz KURTMAN, Şaban Çakır GÖKÇE

Seminoma in A Case of Testicular Feminization Syndrome: Patient Outcome After 7 Years of Follow-up

Bu çalışmada, testiküler feminizasyon tanısı konan ve inmemiş testiste seminom gelişmiş 23 yaşında bir hasta bildirilmiştir. Kandan alınan kromozomların sitogenetik analizinde 46 XY karyotipi bulundu. Laparoskopide uterus olduğu düşünülen sert bir yapı bulundu. Sağ gonad pelvik duvar içerisinde 10 X 15 mm ebadında, fusiform, solid kitle olarak bulundu. Sol gonad yoktu. Sağ gonadektomi uygulandı. Patoloji atrofik testisten gelişen seminoma sonucu olarak rapor edildi. Hasta 6 MV foton LINAC kullanılarak günde 2 Gy fraksiyon ile toplam 26 Gy ışınlandı. Bu seminoma olgusu operasyon sonrası 7 yıl nüksetmemiş olarak takip edildi.

Anahtar Kelimeler:

Testiküler feminizasyon sendromu, seminoma, radyoterapi.

Testiküler Feminizasyon Sendromunda Gelişen Seminoma: Hastanın 7 Yıllık Takibi

This is a case of a young woman who had testicular feminization and deveioped a seminoma in an undescended testis. This patient admitted to the gynecology service with the complaint of primary amenorrhea. Cytogenetic analysis of chromoso-mes from blood demonstrated a 46, XY karyotype. At iaparoscopy a strict structure beieived to be uterus was noted. The right gonad was found 10x15 mm in size, solid, fusiform, on the pelvic sidewall. There was no left gonad. The procedure was ter-minated following right gonodectomy. Pathology had reported the result as seminoma deveioped in the atrophic testis. She trea-ted with irradiation lor a total dose of 26 Gy in 2 Gy daily fractions by using 6 İ/İV photons of linear accelerator. No recurrence has been found during the postoperative foiiow-up period of 7 years.

Keywords:

Testicular feminization syndrome, seminoma, radiotherapy.,

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