Oxidative Stress Manifestation for Community-Acqiured Pneumonia in Children Living in Endemic Area of Iodine Deficiency
Objective: We aimed to evaluate the state of oxidative stress, level of molecular dam- age in relationship with the subcellular distribution of iodine in patients with com- munity-acquired pneumonia from the iodine deficiency region. Materials and Methods: Our study involved 70 children, 4-14 years old, with CAP (moderate severity in 35 children (Group 1); severe - in 35 (Group 2)) and 35 healthy children of the control group (Group 3). The state of organificated/inorganic, antiox- idant defense system, stress-dependent systems, apoptosis and the level of molecular damage were assessed in serum samples. Results: Lower concentration of organificated iodine (12% and 59%, respectively) and high concentration of inorganic iodine (21% and 48%, respectively) were found in Groups 1 and 2. Patients of Group 2 had an inverse relationship between the lev- els of iodine distribution for the organic and inorganic iodine (r = - 0.645, p
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- ISSN: 2147-9488
- Yayın Aralığı: Yılda 4 Sayı
- Başlangıç: 2012
- Yayıncı: HACETTEPE ÜNİVERSİTESİ
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