Peptik Ülser Perforasyonu Nedeniyle Opere Edilen Hastaların Retrospektif Analizi: Tek Merkez Sonuçları

Giriş Peptik ülser perforasyonu aşırı mide asidi üretimi veya azalmış mukozal savunma nedeniyle gastrointestinal sistem mukozasında gelişen tam kat defektler sonucu oluşur. Peptik ülser perforasyonunda tanı ve tedavisinin gecikmesi nedeniyle mortalite ve morbidite artmaktadır. Bu çalışma ile kliniğimizde peptik ülser perforasyonu nedeniyle cerrahi uygulanan hastalarla ilgili deneyimimizi aktarmayı planladık. Gereç-Yöntem Çalışmamızda kliniğimizde Mayıs 2020 ile Ocak 2022 tarihleri arasında peptik ülser perforasyonu nedeniyle cerrahi uygulanan hastaların verileri retrospektif olarak incelenmiştir. Bulgular Çalışmaya 4’ü (%20) kadın, 16’sı (%80) erkek olmak üzere toplam 20 hasta alındı. Hastaların medyan yaşları 47,5 (27-90) idi. Medyan ameliyat süresi 45 (30-75) dakika idi. Hastaların 17’sinde (%85) defekt omental yama ile onarılırken 3’ünde (%15) ise falsiform ile yama yapıldı. Hastanede kalış süresi ortalama 3,5 (2-5) gün idi. Sonuç Peptik ülser perforasyonunda tedavisinde uygulanacak cerrahi teknikler çeşitli olup, en sık tercih edilen yöntem laparoyomiyle omental yama onarımıdır. Perforasyonun tekrarlanmasını önlemek için Helicobacter pylori eradikasyon tedavisi ve kontrolü yapılmalıdır.

Anahtar Kelimeler:

peptik ülser, perforasyon, acil cerrahi

Retrospective Analysis of Patients Operated for Peptic Ulcer Perforation: Single Center Results

Introduction Peptic ulcer perforation is a full-thickness defect in mucosa due to excessive gastric acid production or decreased mucosal defense. Mortality and morbidity increase in peptic ulcer perforation due to delayed diagnosis and treatment. This study aimed to present our experience with patients who underwent surgery for peptic ulcer perforation in our clinic. Material-Method The data of patients who underwent surgery for peptic ulcer perforation between May 2020 and January 2022 in our clinic were retrospectively analyzed. Results A total of 20 patients, 4 (20%) female and 16 (80%) male were included in the study. The median age of the patients was 47.5 (27-90). The median operative time was 45 (30-75) minutes. In 17 (85%) patients, the defect was repaired with an omental patch, and in 3 (15%) patients with a falciform patch. The mean hospital stay was 3.5 (2-5) days. Conclusion Surgical techniques to be applied in treating peptic ulcer perforation are various, and the most preferred method is omental patch repair by laparotomy. In addition, Helicobacter pylori eradication treatment and control should be performed to prevent recurrence of perforation.

Keywords:

peptic ulcer, perforation, emergency surgery,

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