Erdener BALIKÇI, M. Orhan AYYILDIZ, Naci TİFTİK, Dede ŞİT, Ömer METE, Orhan YAZANEL

Nötropenik Kanser Hastalarından İzole Edilen Bakteriyel Ajanların İmipenem Duyarlılıkları

Hematoloji kliniğinde takip edilen nötropenik kanser hastalarından izole edilen çeşitli bakteriyel ajanların imipeneme duyarlılıkları araştırıldı. İzole edilen toplam 56 bakteriyel etkenin duyarlılık işlemleri agar-disk diffüzyon metoduyla gerçekleştirildi. Etkenlerin 16’sı E. Coli, 10’u Pseudomonas spp, 12’si Enterobacter spp, 5’i Proteus spp, 5’i Klebsiella, 8’i Stafilokok olarak tespit edildi. Bu etkenlerin imipeneme duyarlılıkları sırasıyla 16 E. Coli suşunun 13’ünde (%81,2), 10 Pseudomonas suşunun 8’inde (%80), 12 Enterobacter suşunun 10’unda (%83,3), 5 Proteus suşunun 4’ünde (%80), 5 Klebsiella suşunun 3’ünde (%60), 8 Stafilokok suşunun 6’sında (%75) olarak bulundu.Sonuç olarak imipenemin, nötropenik kanser hastalarındaki bakteriyel ajanlara karşı önemli oranda duyarlılığı olan bir antibakteriyel olduğu gözlendi.

Anahtar Kelimeler:

Nötropeni, İmipenem

Susceptibilities of Bacterial Agents Isolated from Neutropenic Cancer Patients to Imipenem

Susceptibilities of various bacterial agents to imipenem isolated from neutropenic cancer patients followed in the department of Hematology were investigated. Susceptibility procedures of totally 56 isolated bacterial agents were carried out by agar-disc diffusion method. Of the agents ,16 were found as E. Coli, 10 as Pseudomonos spp, 12 as Enterobacter spp, 5 as Proteus spp, 5 as Klebsiella, and 8 as Staphyloccocus. The susceptibility of these agents to Imıpenem was identified in 13 of 16 E. Coli strain (81.2%), 8 of 10 Pseudomonas strain (80%), 10 of 12 Enterobacter strain (83.3%), 4 of 5 Proteus strain (80%), 3 of 5 Klebsiella strain (60%) and 6 of 8 Staphyloccocus strain (75%).Consequently, it was observed that Imipenem is an antibacterial agent that has significant efficacy against bacterial agents in neutropenic cancer patients.

Keywords:

Neutropenia, Imipenem,

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