Gamze UĞURLUER, Banu ATALAR, Hayriye Aslı Saran İKİZLER, Nihat SÖZER, Mustafa KİBAR, Meltem SERİN, Enis ÖZYAR

Serviks Kanserli Hastalarda PET/BT Tetkikinde Primer Tümörün FDG Tutulum Derecesi ile Lenf Nodu Metastazı Arasındaki İlişki

Amaç: Bu çalışmada, serviks kanserli hastalarda Pozitron Emisyon Tomografisi/Bilgisayarlı Tomografi PET/BT tetkikinde primer tümörün FDG tutulum derecesi ile lenf nodu metastazı arasındaki ilişkinin saptanması amaçlandı.Gereç ve yöntem: Tedavi öncesi evreleme amacıyla PET/BT tetkiki yapılan 103 hasta çalışmaya dahil edildi. Primer tümörün maksimum standart uptake SUVmaks değeri, PET/BT tetkikinde ölçülen maksimum tümör çapı, pelvik ve paraaortik lenf nodlarında FDG tutulumu olup olmadığı ve FDG tutulumu olan lenf nodlarında SUVmaks değerleri her hasta için kaydedildi. SUVmaks değerlerinin lenf nodu metastazı ile ilişkisi araştırıldı. İstatistiksel analiz SPSS programı ile yapıldı. Bulgular: Ortanca yaş 56 idi 31-91 arası . SUVmaks ortalama değerleri primer tümör için 14,3±6,3 3,9-34,2 arası ve lenf nodları için 8,6±3,9 2,8-19,3 arası idi. Lenf nodu tutulumu olan ve olmayan hastalarda SUVmaks ortalama değerleri sırasıyla 15,9 4,1-34,2 arası ve 11,9 3,9-25,5 arası idi p 4 cm olan hastaların %66’sında lenf nodu tutulumu vardı. SUVmaks değerleri ve lenf nodu FDG tutulumu açısından iki grup arasındaki fark istatistiksel olarak anlamlıydı p

Correlation Between Pet/ct Primary Tumor Fdg Uptake Levels and Lymph Node Metastases In Patients With Cervical Cancer

Objectives: The aim of this study was to determine the correlation between Positron Emission Tomography/Computed Tomography PET/CT primary tumor FDG uptake levels and lymph node metastases in cervical cancer patients.Materials and methods: One hundred and three 103 cervical cancer patients who had pretreatment staging PET/CT were included in the study. Primary tumor maximum standard uptake value SUVmax levels, maximum tumor diameter measured on PET/CT, FDGavid pelvic and paraaortic lymph nodes and SUVmax values for FDG-avid lymph nodes were recorded for every patient. Correlation between SUVmax levels and lymph node metastases were evaluated. Statistical analysis was done using SPSS. Results: Median age was 56 years range 31-91 years . Mean SUVmax levels for primary tumor and for lymph nodes were 14,3±6,3 range; 3,9-34,2 and 8,6±3,9 range; 2,8-19,3 , respectively. SUVmax levels for the patients with FDG-avid lymph nodes and non FDG-avid patients were 15,9 range; 4,1-34,2 and11,9 range; 3,9-25,5 p 4 cm there were lymph node metastases. Two groups were statistically different according to the SUVmax levels and lymph node metastases p

Keywords:

cervical cancer, PET/CT, SUVmax, lymph node metastases,

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