Mustafa YILDIRIM, Cem PARLAK, Mustafa YILDIZ, Nurullah BÜLBÜLLER, Cem SEZER, Çağlar YILDIRIM, Çetin KAYA, Elif PEŞTERELİ

SAFRA KESESİNDE HEPATOİD ADENOKARSİNOM: OLGU SUNUMU

Hepatoid adenokarsinom, hepatoselüler karsinoma benzeyen ve nadir görülen ekstrahepatik bir tümördür. Tümör hücreleri hem fonksiyonel hemde morfololojik olarak hepatositlere benzer. Çoğu olguda AFP serum düzeyi yüksektir. Tümör hücreleri AFP, CEA, CK-8 ve CK-18 ile positif immünboyanma gösterirler. Hepatoid adenokarsinom tanısı için hepatoselüler karsinom ekarte edilmelidir. Agresif bir doğal seyri olmasına rağmen bazen yavaş seyirli olabilir ve uzak yerlere metastazla hastalık tekrarlayabilir. Bu yazımızda over Hepatoid adenokarsinomu nedeni ile opere edilen ve 3 yıl sonra safra kesesinde Hepatoid adenokarsinom nüksü olan olguyu sunuyoruz

Hepatoid Adenocarcinoma In Gallbladder: a Case Report

Hepatoid adenocarcinoma is a rare extrahepatic tumor, resembling hepatocellular carcinoma. It resembles hepatocytes both morphologically and functionally. Serum level of AFP is high in most cases. They reveal positive immunostaining with AFP, CEA, CK-8 and CK-18. To make the diagnosis of Hepatoid adenocarcinoma, hepatocellular carcinoma should be ruled out. Although it has an aggressive natural history, some cases like ours may show slower course, and recur in distant sites. In this article, we present a case of ovarian Hepatoid adenocarcinoma who presented with tumor in gallbladder having similar histopathology after 3 years of initial diagnosis

Keywords:

gallbladder, hepatoid adenocarcinoma, ovary, metastasis,

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