Kök Hücre Nakli ve COVID-19 Pandemisi

Malign ya da malign olmayan nedenlerle hematopoietik kök hücre nakli yapılan hastalar, bağışıklık sistemi baskılanmış bir grup olduğundan COVID-19 ile karşılaşmaları açısından potansiyel olarak riskli olarak kabul edilmektedir. Bu hasta grubunun immünsüpresyon ile viral replikasyonu kontrol etme kabiliyetinin azalması hastanın durumunu ağırlaştırıcı bir faktör ya da aynı zamanda enflamatuar fazı azalttığı için koruyucu bir faktör de olabileceği düşünülmektedir. Pandemi nedeniyle kök hücre nakli merkezleri COVID-19 önleme ve semptom yönetimi ile ilgili kılavuzları takip etmeleri gerekmektedir. Bu derleme, pandemi sürecinde hematopoietik kök hücre nakli hastalarının tedavi ve bakım sürecinin incelenmesi amacıyla hazırlanmıştır.

Anahtar Kelimeler:

COVID-19, Pandemi, Kök hücre nakli

Stem Cell Transplantation and COVID-19 Pandemic

Patients undergoing hematopoietic stem cell transplantation for malignant or non-malignant reasons are considered to be potentially at risk for encountering COVID-19, as they are an immunocompromised group. The decrease in the ability of this patient group to control viral replication with immunosuppression is thought to be an aggravating factor or at the same time a protective factor as it reduces the inflammatory phase. Due to the pandemic, stem cell transplant centers are required to follow guidelines on COVID-19 prevention and symptom management. This review has been prepared to examine the treatment and care process of hematopoietic stem cell transplant patients during the pandemic period.

Keywords:

COVID-19, Pandemic, Stem cell transplantation,

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