Posterior Reversible Encephalopathy Syndrome Associated with Henoch-Schönlein Purpura
Giriş: Henoch-Schönlein purpurası (HSP) primer olarak çocukları etkileyen akut bir vaskülittir. Merkezi sinir sistemi tutulumu ve karakteristik döküntülerden önce nörolojik komplikasyonların ortaya çıkması nadirdir. Posterior reversibl ensefalopati sendromu (PRES) ve serebral vaskülit HSP nın nörolojik komplikasyonlarıdır. Olgu: Konvülziyon, bilinç kaybı ve total görme kaybı ile başvuran 5 yaşındaki bir kız olgusu sunulmuştur. Nörolojik semptomlar ön planda olup, karekteristik döküntü yoktu. Radyolojik bulguları PRES ile uyumluydu. Klinik bulgular HSP için atipikti. Böbrek tutulumu ve hipertansiyon yoktu. Klinik bulgular kortikosteroid tedavisi ile düzeldi. Sonuç: Hastamız tipik HSP döküntülerinden önce santral sinir sistemi bulgularının ortaya çıkması ve hipertansiyonun olmaması nedeniyle ilginçtir. HSP nin santral sinir sistemi komplikasyonu ile başvurmuştur.
Henoch-Schönlein Purpurası İlişkili Posterior Reversible Ensefalopati Sendromu
Introduction: Henoch-Schönlein purpura (HSP) is an acute vasculitis that primarily affects children. Central nervous system (CNS) involvement and the appearance of neurological complications preceding the characteristic rash are rare. Posterior reversible encephalopathy syndrome (PRES) and cerebral vasculitis are neurological complications of HSP. Case Presentation: We describe a case of 5-year-old girl who presented with seizures, loss of consciousness, and total loss of vision. Her HSP was atypical because the presenting symptoms were neurological complications rather than the characteristic rash, and her radiological features were compatible with PRES. She did not have re- nal impairment or hypertension. Her abnormal findings resolved following a standard course of corticosteroids. Conclusion: Our case is atypical because of the presence of CNS involvement before the characteristic rash with the absence of hypertension. The patient's HSP presented as a complication of cerebral vasculitis.
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