Mehmet Bilgehan YÜKSEL, Bülent GÜNLÜSOY, Ali Rıza AYDER

BPH ile eşzamanlı detrüsör aşırı aktivitesi DAA sıklığının değerlendirilmesi: Karakteristik klinik BPH parametrelerinin eşzamanlı DAA mevcudiyeti ile ilişkisi var mı?

Amaç: Benign prostat hiperplazisine BPH eşlik eden detrüsör aşırı aktivitesinin DAA prevalansını araştırmak ve karakteristik BPH parametreleri ile eşzamanlı DAA varlığı arasındaki olası ilişkiyi değerlendirmek.Gereç ve yöntem: Bu çalışmada DOA olduğu bilinmeyen klinik BPH’lı 100 hasta prospektif olarak değerlendirildi. Tüm hastalar operasyon öncesi dönemde ürodinami ile değerlendirildi. Hastalar ürodinami sonuçlarına göre iki gruba ayrıldı Grup 1: Pür BPH, Grup 2: BPH+DAA . İki grup arasında bazı klinik BPH parametreleri istatistiksel olarak karşılaştırıldı.Bulgular: Dolum sistometri sonuçları 52 %52 hastada DAA varlığını gösterdi. Basınç akım çalışmasında tüm hastalarda obstruktif işeme bulguları belirlendi. Tek değişkenli analizde, DAA’ lı hastalar daha yaşlı idi ve anlamlı biçimde daha düşük Q max, daha yüksek kreatinin düzeyi, daha yüksek IPSS ve AAM V-8 skoruna sahipti. Diğer yandan çok değişkenli analizde sadece yaş, IPSS ve AAM V-8 skorları bağımsız olarak eşzamanlı DAA varlığı ile ilişkili bulundu.Sonuç: Klinik BPH hastalarında eşzamanlı DAA varlığı bağımsız olarak sadece yaş, IPSS ve AAM V-8 skorları ile ilişkilidir. Daha önceden koyulmuş klinik BPH tanısı olan ve uzun süredir buna yönelik tedavi almasına karşın LUTS semptomları devam eden hastalarda eşzamanlı DAA aktivitesini her zaman dikkate almak ve bu tür hastalara yaklaşımda AAM V-8 sorgulamasını rutin olarak kullanmak oldukça mantıklı ve isabetli bir yaklaşım olacaktır

Anahtar Kelimeler:

Benign prostat hiperplazisi, detrüsör aşırı aktivitesi, alt üriner sistem semptomları, ürodinamik inceleme

The evaluation of the prevalence of DOA concomitant to BPH: May the characteristic parameters of clinical DOA have any relationships with the presence of concomitant DOA?

Objective: To investigate the prevalence of detrusor overactivity DOA concomitant to clinical benign prostate hyperplasia BPH and the relationship between some of the characteristic parameters of BPH and the presence of concomitant DOA.Materials and methods: This is a prospective analysis of 100 patients with a previous diagnosis of clinical BPH and no previous diagnosis of DOA. All patients were urodynamically evaluated and divided in two groups Group 1: Pure BPH, Group 2: BPH with DOA . Some characteristic parameters of BPH were statistically compared between two groups.Results: Filling cystometry results showed that 52 men %52 had detrusor overactivity. In pressure-flow studies, obstructive voiding findings were determined in all patients. In univariate analysis, patients with DOA were significantly older, had lower Q max, higher creatinine, higher IPSS and OAB V-8 scores. On the other hand, multivariate analysis revealed that only age, IPSS, and OAB V-8 scores were independently associated with the presence of DOA.Conclusion: In BPH patients, the presence of concomitant DOA is independently associated with only age, IPSS, and OABV8 scores. It will be very logical to consider concomitant DOA and especially to routinely use OAB questionnaire in the management of patients with previous diagnosis of clinical BPH and ongoing LUTS despite receiving prolonged medical treatment

Keywords:

Benign prostate hyperplasia, detrusor overactivity, lower urinary tract symptoms, urodynamic testing,

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