Anjiomatoid Fibröz Histiositom

Anjiomatoid fibröz histiositom nadir görülen bir yumuşak doku tümörüdür. Düşük grade malign potansiyele sahiptir. En sık görülme yerleri alt ve üst ekstremitelerdir. Ekstremiteleri gövde, boyun ve nazolabial bölge takip eder. Literatür taramasında skalpte angiomatoid fibrous histiositoma bulunan bir olgu saptanmadı. Bu sunumda oksipital yerleşimli anjiomatoid fibröz histiositom tanısı alan bir olgu literatür eşliğinde tartışıldı.

Angiomatoid Fibrous Histiocytoma

Angiomatoid fibrous histiocytoma is a rare soft tissue tumor. It has low-grade malign potential. Angiomatoid fibrous histiocytoma is usually detected in the lower and upper extremities. Lesions are most commonly found in the extremities, followed by the body, neck, and nasolabial region. A literature search did not reveal any cases of angiomatoid fibrous histiocytoma in the scalp. In this report, a case diagnosed with angiomatoid fibrous histiocytoma located on the occipital region is discussed with references to the literature.

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  • 1. Enzinger FM. Angiomatoid malignant fibrous histiocytoma: a distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. Cancer 1979;44:2147-2157.
  • 2. Costa MJ, Weiss SW. Angiomatoid malignant fibrous histiocytoma: a follow-up study of 108 cases with evaluation of possible histologic predictors of outcome. Am J Surg Pathol 1990;14:1126-1132.
  • 3. De Nictolis M, Tommasoni S, Goteri G, Giangiacomi M, et al: Angiomatoid malignant fibrous histiocytoma. Clinico-pathologic and immunohistochemical study of a case. Minerva Chir 1993;15:48:649-652.
  • 4. Chow LT, Ailen PW, Kumta SM, et al: Angiomatoid malignant fibrous histiocytoma: report of an unusual case with highly aggressive clinical course. J Foot Ankle Surg 1998;37:235-238.
  • 5. Silverman JS, Lomvardias S: An unusual soft tissue tumor with features of angiomatoid malignant fibrous histiocytoma composed of bimodal CD34 and factor Xllla positive dendritic celi subsets. CD34 and factor XII la in angiomatoid MFH. Pathol Res Pract 1997;193:51-58.
  • 6. Xıang L, Zhou J, Gu W, Yang B. Retroperitoneal angiomatoid fibrous histiocytoma: A case report and review of the literature. Oncology Letters 2013;5:1833-1835.
  • 7. Thway K, Stefanaki K, Papadakis V, Fisher C. Metastatic angiomatoid fibrous histiocytoma of the scalp, with EWSR1-CREB1 gene fusions in primary tumor and nodal metastasis. Human Pathology 2013;44:289–293.
  • 8. Song JY, Lee SK, Kim SG, et al: Angiomatoid fibrous histiocytoma on the hard palate: case report. Oral Maxillofac Surg 2012;16:237-242.
  • 9. Rullo R, Ferraraccio F, Serpico R, et al: Oral fibrous histiocytoma and its angiomatoid variant. J Craniomaxillofac Surg 2012;40:435-438.
  • 10. Patrizi A, Tabanelli M, Filippi G, et al: An angiomatoid fibrous histiocytoma over the left pre auricular region in a 13-year-old boy. Dermatol Online J 2010;16:4.
  • 11. Hallor KH, Micci F, Meis-Kindblom JM, et al: Fusion genes in angiomatoid fibrous histiocytoma. Cancer Lett 2007;251:158-163.
  • 12. Fanburg-Smith JC. Miettinen M: Angiomatoid "malignant" fibrous histiocytoma: a clinicopathologic study of 158 cases and further exploration of the myoid phenotype. Hum Pathol 1999;30:1336-1343.
  • 13. Davis AM, O'Sullivan B, Turcotte R, et al: Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma. Radiother Oncol 2005;75:48-53.
  • 14. Matsumura T, Yamaguchi T, Tochigi N, et al: Angiomatoid fibrous histiocytoma including cases with pleomorphic features analysed by fluorescence in situ hybridisation. J Clin Pathol 2010;63:124-128.
  • 15. García JJ and Folpe AL: The impact of advances in molecular genetic pathology on the classification, diagnosis and treatment of selected soft tissue tumors of the head and neck. Head Neck Pathol 2010;4:70-76.
  • 16. Lee HS, Kim T, Kim JS, et al: Angiomatoid fibrous histiocytoma as a second tumor in a young adult with testicular cancer. Cancer Res Treat 2013;45:239-243.
  • 17. Enzinger FM, Weiss SW: Fibrohistiocytic tumors of intermediate malignancy. Soft tissue tumors. St.Louis: Mosby 3rd ed, 1995;324-349.
  • 18. Grossman LD, White RR and Arber DA: Angiomatoid fibrous histiocytoma. Ann Plast Surg 1996;36:649-651.
Uluslararası Klinik Araştırmalar Dergisi-Cover
  • ISSN: 2148-0281
  • Başlangıç: 2013
  • Yayıncı: Çanakkale Onsekiz Mart Üniversitesi
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