Covid-19 Hastalarının Tedavisinde Moleküler Hidrojen İnhalasyonunun Potansiyel Uygulaması
COVID-19 (Corona Virüs Hastalığı 2019), SARS-CoV-2 suşunun neden olduğu ciddi ve akut solunum sendromu hastalığıdır. İlk COVID-19 vakası Aralık 2019'da ortaya çıkmış ve aylar içinde tüm dünyada görülen salgın haline gelmiştir. Moleküler hidrojen (H2); reaktif oksijen türlerini seçici olarak süpürmesi, inflamatuar sitokinlerin inaktivasyonu, antiapoptotik özelliği sayesinde birçok hastalık üzerinde etkili bir tedavi yöntemi olarak kullanılmaktadır. Özellikle inflamatuar akciğer yaralanmaları tedavisinde H2’nin terapötik etkileri, COVID-19 hastalığını hafifletebileceği görüşünü desteklemektedir. Aynı zamanda, H2 erken aşamada COVID-19 sırasında SARS-CoV-2'nin neden olduğu yıkıcı sitokin fırtınasını ve akciğer hasarını azaltabilir. Bu nedenle moleküler hidrojen tedavisi, COVID-19 için yeni ve etkili bir tedavi yöntemi olma potansiyeline sahiptir. Fakat bu hipotezin doğrulanması için daha fazla klinik denemelere ihtiyaç vardır.
Anahtar Kelimeler:
COVID-19, Oksi-Hidrojen, Moleküler hidrojen, SARS-CoV-2, Sitokin fırtınası
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- ISSN: 2757-8100
- Başlangıç: 2020
- Yayıncı: Bursa Uludağ Üniversitesi
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