Bu çalışmada beden sıcaklığı, solunum sayısı, kalp frekansı artışı ve öksürük gibi solunum sistemi hastalıkları kompleksi belirtileri gösteren 20 danada amoksisilin ile trimethoprim + sulfadoksin kombinasyonunun etkilerinin karşılaştırılması amaçlandı. Sağaltım aşamasında hasta hayvanlar iki farklı gruba ayrılarak, 7 gün süre ile I. gruba (n=10) 10 mg/kg dozunda amoksisilin ve II. gîuba (n=10) 15 mg/kg dozunda trimethoprim + sulfadoksin kombinasyonu im. yolla uygulandı. Klinik ve hematolojik muayeneler sağaltım öncesi ve çalışmanın 1., 3., 5., 7.,10. günleri tekrar edildi. Beden sıcaklığının I. grupta birinci (p

In this study it was aimed to compare the effects of amoxycilline and trimethoprim + sulphadoxine combination in 20 cattle with clinical signs of bovine respiratory disease complex such as high temperature, respiration and heart rate and cough. At the stage of treatment sick animals were divided into two groups; amoxycillin at the dosé of 10 mg/kg, was administered to group I (n=10), and trimethoprim + sulfadoxine combination, at the dose of 1.5 mg/kg, was administered to group II (n=10) by im. route for 7 days. Clinical and hematological examinations before the treatment were repeated in the 1st, 3th, 5th, 7th, 10th days of the study. Body temperature was observed to decrease from the 1stday in group I and from the 3th day in group II (p<0.001). Similarly, respiration rate was determined to decline from the 3 day in both groups. Also, a decrease in the heart rate was observed from the 3th day in group I and from the 5th day in group II (p<0.001). As a conclusion, although both antibacterials used in the treatment of bovine respiratory disease complex are effective, at the group in which amoxycilline was used quick remission of the clinical signs was observed.