Müjdem Nur AZILI, Gülsen KESKİN, Sengül ÖZMERT, Tuğrul TİRYAKİ, Gülşah KABAÇAM, Halil ATAYURT

Primer Obstrüktif Megaüreterde Cerrahi Tedavi; 22 Olgunun Değerlendirmesi

Amaç: Obstrüktif megaüreter prenatal hidronefroz saptanan olguların %10’nu oluşturur. Prenatal tanılı olguların artmasıyla birlikte obstrüktif megaüreterli olguların izlemi ve tedaviside son yirmi yılda değişiklikler görülmektedir. Kliniğimizde primer obstrüktif megaüreter tanısı ile cerrahi girişimde bulunulan olgular sunularak tedavi sonuçları literatür bilgileri ışığında tartışılacaktır.Gereç ve Yöntem: 2007-2011 yılları arasında primer obstrüktif megaüreter tanısı ile cerrahi girişimde bulunulan 22 olgu hastane kayıtlarından geriye dönük olarak değerlendirildi. Obstrüktif megaüreter tanısı ile izlenen olgularımızda artan renal pelvis çapı, azalan renal fonksiyon, tekrarlayan idrar yolu enfeksiyonu ve flank ağrısı cerrahi müdahale için aranan şartlar oldu.Bulgular: Sekiz kız, 14 erkek toplam 22 olgu geriye dönük olarak değerlendirmeye alındı. Olguların yaşları ortalama 2.23± 2.42 (1 ay–8 yaş) yıldı . Dört olguda sağ üreter, 17 olguda sol üreterde, bir olguda ise bilateral obstrüksiyon saptandı. 11 olgumuz prenatal saptanan hidronefroz nedeni ile araştırılırken tanı aldı. Soliter böbreği olan üç olgumuza bir yaş altında erken dönemde girişimde bulunuldu. Ürosepsiste olan bir olguya ise üreterokutaneostomi açıldı ve bir yaşından sonra definitif onarım yapıldı. 18 olgumuz açık cerrahi girişim ile üreter çapı azaltıldıktan sonra üreteroneosistostomi yapılarak, dört olgumuz da JJ kateter takılarak izlendi.Tartışma: Primer obstrüktif megaüreter ender karşılaşılan üriner sistem anomalisidir. Tedavisinde halen görüş birliği oluşmamıştır. Özellikle antenatal hidronefroz ile tanınan olgularda izlem tartışmalıdır. Endoskopik olarak JJ katerer takılarak izlenebileceği ifade edilse de serimizdeki olguların çoğunda endoskopik kateter yerleştirmek mümkün olmamıştır. Bu tür olgularda gerekli olduğunda geçici üreterokutaneostomi yapılırken bir yaşın üzerinde üreter çapını azaltarak üreteroneosistostomi yapılması uygun seçenektir. Özellikle soliter böbrekli olgularda erken dönemde açık cerrahi girişim yapılması gerekebilir.

Anahtar Kelimeler:

Obstrüktif megaüreter

OPERATIVE TREATMENT OF THE PRIMARY OBSTRUCTIVE MEGAURETER; EVALUATION OF 22 PATIENTS

Aim: Obstructive megaureter composes 10% of the prenatally diagnosed cases of hydronephrosis. During the recent 20 years, some changes have appeared in the follow-up and treatment of the cases with obstructive megaureter in conjunction to the increase in prenatally diagnosed cases. In this article, cases of obstructive megaureter operated in our clinic has been presented and results of treatment have been discussed on the basis of literature knowledge.Materials and methods: 22 cases operated for the diagnosis of obstructive megaureter between 2007 and 2011 were evaluated retrospectively by the hospital records. Increasing renal pelvis diameter, decreasing renal functions, recurrent urinary tract infection and flank pain were the parameters for indication of surgical intervention in these cases of obstructive megaureter.Results: Total of 22 cases (8 girls and 14 boys) with the mean age of 2.23± 2.42 years (age range: 1 month-8 years) were evaluated retrospectively. Obstruction was determined at the right ureter in 4 cases, at the left ureter in 17 cases, and bilateral in one case. Eleven cases were diagnosed during investigation for prenatally identified hydronephrosis. Early surgical intervention was performed in 3 cases with solitary kidney under the age of one. Ureterocutaneostomy was carried out for one case with urosepsis and definitive operation was conducted after one year of age. Ureteroneocystostomy was performed for 18 cases by reducing the diameter of the ureter, whereas 4 cases were followed up after a JJ catheter was placed. Discussion: Primary obstructive megaureter is a rare urinary system abnormalities. There is no consensus on the treatment of this disease, yet. Follow-up is controversial especially in cases recognized as antenatal hydronephrosis. Although these cases could be followed by endoscopically placing a JJ catheter; this has not been feasible in most of our cases. In such cases, a temporary ureterocutaneostomy can be performed when it is necessary. Furthermore, ureteroneocystostomy by reducing the diameter of the ureter has been a prefered option for cases over one year of age. Open surgery might be necessary especially in cases with solitary kidney at an early stage

Keywords:

Obstructive megaureter,

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