Bronkopulmoner Displazide Önleyici Ve Tedavi Amaçlı İnhale Veya Sistemik Steroid Kullanımı: Güncel Bir Derleme

Bronkopulmoner displazi patogenezinde mekanik ventilasyon kaynaklı basınç ve/veya hacim travması, oksijen toksisitesi, enfeksiyon, azalmış surfaktan üretimi ve artmış akciğer kan akımı ile ilişkilendirilen inflamasyon suçlanır. İnflamasyon sürecinin durdurulması amaçlı sistemik ve inhale steroidler kullanılmaktadır. Bu yazıda, bronkopulmoner displazi tedavisinde kullanılan sistemik ve inhale steroidlerin gözden geçirilmesi ve bu konuda varılan görüş birliğinin tartışılması amaçlanmıştır.

Anahtar Kelimeler:

Bronkopulmoner displazi, prematürite, steroid, tedavi

INHALED OR SYSTEMIC STEROID USE FOR PREVENTIVE AND MANAGEMENT PURPOSES IN BRONCHOPULMONARY DYSPLASIA: A CURRENT REVIEW

Inflammation related to mechanical ventilation induced baro and/or volume trauma, oxygen toxicity, infection, decreased surfactant production and increased pulmonary blood flow is accused for bronchopulmonary dysplasia pathogenesis. Systemic or inhalated steroids are used to stop the inflammatory process. Herein, it is aimed to review the systemic and inhalated steroids used in bronchopulmonary dysplasia and discuss the consensus in this subject

Keywords:

Bronchopulmonary dysplasia, prematurity, steroid, treatment,

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