Serap KİRKİZ, Bahattin TUNÇ, Özlem BİLİR ARMAN, H. Neşe YARALI

Akut Lenfoblastik Lösemili Bir Çocukta Nadir Bir Herpes Virüs Enfeksiyonu: Herpetik Dolama

Herpetik dolama, parmağın herpes simpleks virüs (HSV) tip 1 veya 2 ile enfeksiyonu sonucu oluşur. Sıklıkla herpes gingivostomatitinin otoinokulasyonu sonucu gelişir ve genellikle elin tek parmağı tutulur. Biz de kliniğimizde relaps T hücreli lösemi tanısıyla izlediğimiz 11 yaşında kız hastada fludarabin, sitozin arabinosid ve idarubisinden oluşan yoğun kemoterapi sonrası gelişen febril nötropeni atağı sırasında herpes gingivostomatitinin otoinokulasyonu sonucu oluşan herpetik dolama olgusunu sunduk.

Anahtar Kelimeler:

Akut lenfoblastik lösemi, Herpes simpleks, Paronişi

A Rare Presentation of Herpes Virus Infection in a Child with Acute lymphoblastic leukemia: Herpetic Whitlow

Herpetic whitlow is the infection of fingers by herpes simplex virus (HSV) type 1 or 2. It is frequently caused by autoinoculation of herpes gingivostomatitis and usually one finger of a hand is involved. Here we present a case of an 11-year-old girl having herpetic whitlow by autoinoculation of herpes gingivostomatitis during a febrile neutropenia period while being treated with intense chemotherapy consisting of fludarabin, cytosine arabinoside and idarubicin for a T cell leukemia relapse

Keywords:

Acute lymphoblastic leukemia, Herpes simplex, Paronychia,

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Robayna MG, Herranz P, Rubio FA, Pena P, Pena JM, Gonzalez J, et al. Destructive herpetic whitlow in AIDS: Report of three cases. Br J Dermatol 1997;137:812-15.
Smith E, Hallman JR, Paradasani A, McMichael A. Multiple herpetic whitlow lesions in a patient with chronic lymphocytic leucemia. Am J Hematol 2002;69:285-88.
Barret AP. Chronic indolent orofacial herpes simplex virus infection in chronic leukemia: A report of three cases. Oral Surg Oral Med Oral Pathol 1988;66:387-90.
Wu IB, Schwartz RA. Herpetic whitlow. Cutis 2007;79:193-96.
Sizinnai G, Schaad uB, Heininger u. Multipl herpetic whitlow lesions in a 4-year old girl: Case report and review of the literature. Eur J Pediatr 2001;160:528-33. lezyon.