İneklerde siklusun erken döneminde uygulanan oksitosinin siklus süresi, serum progesteron, plazma vitamin A ve Beta-Karoten düzeyler üzerine etkisi

Effect of oxytocin administered in the early stage of the oestrous cycle on the length of the oestrous cycle and levels of serum progesterone, plasma A vitamin and Beta-carotene in cows

The purpose of this study was to analyse the effect of the application of oxytocine in the early stage of the oestrous cycle on the levels of serum progesterone and plasma vitamin A and ß-carotene during the cycle. Five Swiss-Brown cows were used during two oestrous cycles. Blood samples were collected during the first cycle starting after synchronization and then a total daily dose of 100 I.U. oxytocine was applied subcutanously as a half dose at 12 hour intervals on days on 4, 5 and 6 of the second cycle. During the same cycle, blood samples were again collected, from which serum and plasma were extracted. The levels of serum progesterone and plasma vitamin A and ß-carotene were determined from each sample and the correlations between these parameters were investigated. A statistically significant negative correlation was present between serum progesterone and plasma ß-carotene levels during the second cycle in cows (P

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  • 1. fienel, S.: Hayvan Besleme. ‹st. Üniv. Veteriner Fakültesi Yay›nlar›. ‹stanbul,1986.
  • 2. Hurley, W.L. and Doane, R.M.: Recent Developments in the Roles of Vitamins and Minerals in Reproduction. 1989; 72, 784-804.
  • 3. Hemken, R.W. and Bremel, D.H.: Possible Role of ß-Carotene in Improving Fertility in Dairy Cattle. J. Dairy Sci., 1982; 65, 1069- 1073.
  • 4. Skopets, B.G.: Effect of Vitamin A and ß-Carotene on Immunoreactivity and Success in Calving. Zhivotnovodstvo. 1986; 1, 49-50.
  • 5. Iwanska, S., Lewicki, C. and Rybicka, M.: The Effect of ß-Carotene supplementation on the ß-Carotene and Vitamin A Levels of Blood Plasma and Some Fertility indices of Dairy Cows. Arch. Tierernahr., 1985; 35, (8): 563-570.
  • 6. Salmanoğlu, R., Bafltan, A., Salmano¤lu, B., Küplülü, fi. ve Vural, R.: Çeflitli Fertilite Proplemli Holfltayn Irk› ‹neklerde Kan ß-Karoten, Retinol, Glikoz ve Kolesterol Düzeyleri. Ankara Üniv. Vet. Fak. Derg. 1997; 44, 151-157.
  • 7. Dembinski, Z., Bronicki, M. and Trenti, F.: Concentration of Progesterone (P-4) in the Blood of Obtaining Different Amounts of ß-Carotene in Food. Proceedings 18th World Buiatrics Congress: 26th Congress of the Italian Association of Buiatrics, Bologna. 1994; 1, 325-328.
  • 8. Stolla, R., Porzig, R. and Leidl, W.: Effects of Feeding ß-Carotene on the Fertility of Cattle. 2. Effects on Fertility. Berliner und Munchener Tierrarztliche Wochenschrift, 1987; 100, (3): 90-95.
  • 9. Ahlswede, L. and Lotthammer, K. H.: Specific Vitamin-A-Unrelated Effect of ß-Carotene on the Fertility of Cattle. V. Studies of Organs (ovaries, corpora lutea, liver, fat tissue, uterus fluid, adrenals) Determinations of Weights and Contents. Deutsche Tierarztlicne Wochenschrift. 1978; 85, (1): 7-12.
  • 10. Iwanska, S. and Strusinska, D.: The Effect of ß-Carotene and Vitamins A, D3 and E on Some Reproductive Parameters in Cows. Acta Vet. Hung., 1997; 45, (1): 95-107.
  • 11. Schlenzig, M., Geinitz, D., Ochrimenko, W.I. and Flachowsky, G.: ß-Carotene and Vitamin A in Feeding Heifers. Symposium "Vitamine und Ergotropika" und Podiumsdiskussion zur Verzehrsregulation. Reinhardsbrunn. 1987; 34-40.
  • 12. Folman, Y., Ascarelli, I., Kraus, D. and Barash, H.: Adverse Effect of ß-Carotene in Diet on Fertilitiy of Dairy Cows. J. Dairy Sci., 1987; 70, 357-366.
  • 13. Graves-Hoagland, R.L., Hoagland, T. A. and Woody, C. O.: Effect of ß-Carotene and Vitamin A on Progesterone Production by Bovine Luteal Cells. J. Dairy Sci., 1988; 71, 1058-1062.
  • 14. Jackson, P. B., Furr, B. J. A. and Johnson, C. T.: Endocrine and Ovarian Changes in Dairy Cattle Fed a Low ß-Carotene Diet During an Oestrus Synchronisation Regime. Research in Veterinary Sci., 1981; 31, (3): 377-383.
  • 15. Boos, A.: ß-Carotene and Follicular Cysts in Cattle. Zuchthygiene, 1987; 22, (5): 223-228.
  • 16. Yılmaz, B.: Hormonlar ve Üreme Fizyolojisi. Birinci bask›, Feryal Matbacılık, Ankara, 1999. 17. McCracken, J.A., Custer, E.E. and Lamsa, J.C.: Luteollysis: A Neuroendocrine- Mediated Event. Physiological Reviews, 1999; 79, (2): 263-323.
  • 18. Arthur, G.H., Noakes, D.E. and Pearson, H.: Veterinary Reproduction and Obstetrics (Theriogenology). 5th ed, Bailliere Tindall, London, 1982.
  • 19. Homedia, A.M.: Role of Oxytocin During the Oestrous Cycle of Ruminants with Particular to the Goats. Animal Breeding Abstracts., 1986; 54 (4): 263-268.
  • 20. Kotwica, J., Skarzynski, D. and Jaroszewski, J.: Involvement of Beta-Adrenoceptors in the Regulation of Luteal Function in Cattle. British Veterinary Journal, 1991; 147, (3):189-196.
  • 21. Milvae, R.A. and Hansel, W.: Concurrent Uterine Venous and Ovarian Arterial Prostaglandin F Concentrations in Heifers Treated with Oxytocin. J. Reprod. Fert., 1980; 60, 7-15.
  • 22. Milvae, R.A. and Hansel, W.: Inhibition of Bovine Luteal Function by Indomethacin. J. Anim. Sci., 1985; 60 (2): 528-531.
  • 23. Tsang, P.C.W., Walton, J.S. and Hansel, W.: Oxytocin-Specific RNA, Oxytocin and Progesterone Concentrations in Corpora Lutea of Heifers Treated with Oxytocin. J. Reprod. Fert., 1990; 89, 77- 84.
  • 24. Wilks, J.W. and Hansel, W.: Oxytocin and the Secretion of Luteinizing Hormone in Cattle. J. Anim. Sci., 1971; 33, 1048- 1052.
  • 25. Chew, B.P., Holpuch, D.M. and O'Fallon, J. V.: Vitamin A and ßCarotene in Bovine and Porcine Plasma, Liver, Corpora Lutea and Follicular Fluid. J. Dairy Sci., 1984; 67, 1316-1322.
  • 26. Aksakal, M., Karakılçık, A.Z. ve Kalkan, C.: İnek ve Düvelerin Kan Plazması ß-Karoten ve E vitamini Üzerinde Irk, Yaş, Mevsim, Gebelik ve Laktasyonun Etkileri. Tr. J. of Veterinary and Anim. Sci., 1990; 14, (2) 320-333.
  • 27. Aksakal, M., Karakılçık, A.Z. ve Kalkan, C., Çay, M., Nazıroğlu, M.: İneklerde Üremenin Çeflitli Dönemlerinde ß-Karoten ve E vitamini Düzeyleri. Tr. J. of Veterinary and Anim. Sci., 1995; 19, 1, 59-64.
  • 28. Graves-Hoagland, R.L., Hoagland, T. A. and Woody, C. O.: Relationships of Plasma ß-Carotene and Vitamin A to Luteal Function in Postpartum Cattle. J. Dairy Sci., 1989; 72, 1854- 1858.
  • 29. Schweigert, F. J. and Zucker, H.: Concentrations of Vitamin A, ßCarotene and Vitamin E in Individual Bovine Follicles of Different Quality. J. Reprod. Fert., 1988; 82, 575-579.
  • 30. Suzuki, C. and Katoh, N.: A Simple and Cheap Method for Measuring Serum Vitamin A in Cattle Using a Spectrophotometer. Jpn. J. Vet. Sci., 1990; 52, 1282-1284.
  • 31. Abraham, G.E.: The Application of Natural Steroid Radioimmunoassay to Gynecologic Endocrinology. Ed. G.E. Abraham. In: "Radioassay System in Clinical Endocrinology". Marcel Dekker, Basel, 475-529, 1981.
  • 32. Kubasik, N.P., Hallauer, G.D. and Brodows, R.G.: Evaluation of Direct Solid-Phase Radioimmunoassay for Progesteron Useful for Monitoring Luteal Function. Clinical Chemistry, 30, 2, 284-286, 1984.
  • 33. Feldman, D. and Gagnon, J. Stat View, Brain Power, Inc., Calabasas, CA, 1985.
  • 34. Christensen, D.S., Hopwood, M.L. and Wiltbank, J.N.: Levels of Hormones in the Serum of Cycling Beef Cows. J. Anim. Sci., 1974; 38, (3): 577-583.
  • 35. Henricks, D.M., Dickey, J.F. and Niswender, G.D.: Serum Luteinizing Hormone and Plasma Progesterone Levels During the Estrous Cycle and Early Pregnancy in Cows. Biology of Reproduction, 1970; 2, 346-351.
  • 36. Sreenan, J.M. and Diskin, M.G.: Early Embryonic Mortality in the Cow: Its Relationship with Progesterone Concentration. Vet. Rec., 1983; 112, 517-521.
  • 37. Hansel, W. and Wagner, W.C.: Luteal Inhibition in the Bovine as a Result of Oxytocin Injections, Uterine Dilatation and Intrauterne Infusions of Seminal and Preputial Fluids. J. Dairy Sci., 1960; 43, 796-805.
  • 38. Chandolia, R.K. and Verma, S. K.: Studies on Biochemical Profiles in Anestrus Buffalo Heifers. Indian Vet. J., 1987; 64, 482-484.
  • 39. Kudlac, E., Nedbalkova, J. and Studencik, B.: Contents of ßCarotene and Vitamin A in Blood Serum and Milk of Cows in Relation to Fertility. Veterinarstvi. 1981; 31, (3) 102-104.
  • 40. Tiftik, A. M. ve Nizaml›o¤lu, M.: ‹neklerde Plazma Retinol. ßKaroten Düzeyleri ve Bu Düzeylerle Çeflitli Postpartum Hastal›klar Aras›ndaki ‹liflkiler. Do¤a Tr. J. of Vet. and Anim. Sci., 1992; 16, 177-186.
  • 41. Can, R., Y›lmaz, K. ve Gül, Y.: ‹nfertil ‹neklerde Plazma A vitamini ve ß-Caroten Miktarlar› Üzerinde bir Araflt›rma. Do¤a TÜ. Vet. ve Hay. D., 1986; 10, 1,18-23.
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK