Bu çal›flmada, 7 güvercinde preanestezik olarak medetomidin (M) ve anestezik olarak ketamin (K) uygulamas›n›n anestezi derecesi ve fizyolojik parametrelerde oluflturdu¤u de¤ifliklikler incelenmifltir. Kas içi (im) M (200 µg/kg) uygulamas›n› takip eden 10. dakikada K (120 mg/kg, im) uygulanm›flt›r. M uygulanmadan önce (0. dak.), uygulamay› takiben 10. dakika ile, K uygulamas›ndan sonraki; 5., 15., 30., 45. ve 60. dakikalarda vücut ›s›s›, solunum ve kalp at›m say›lar›, anestezi dereceleri ve EKG bulgular› belirlenmifltir. Bütün güvercinlerin 4. derece anesteziye girdi¤i, kalp at›m say›lar›nda, preanestezinin 10. dakikas›nda bafllayan ve anestezi süresince de devam eden istatistiksel olarak anlaml› (p < 0.01) azalman›n oldu¤u gözlenmifltir. Solunum say›s› preanestezinin 10. dakikas›nda belirgin flekilde azalm›flt›r (p < 0.01). Ketamin uygulamas›n› takip eden 5. dakikada solunum say›s› artmaya bafllam›fl, 30. dakikaya kadar yüksek düzeyde kalm›fl ancak tekrar azalm›flt›r. Kalp at›m say›s› preanestezi döneminde birdenbire (p < 0.01), anestezi döneminde ise kademeli bir flekilde azalm›flt›r (p < 0.05). Elektrokardiyogram bulgular› olarak, sadece P-R ve R-R aral›klar›nda belirgin uzamalar bulunmufltur. Vücut ›s›s›nda hem preanestezi hem de anestezi dönemlerinde süreklibir azalma gözlenmifltir (p < 0.05 veya p < 0.001). Sonuç olarak, M + K anestezi kombinasyonunun güvercinlerde fizyolojik de¤erleri de¤ifltirdi¤i ancak hayati bir tehlike oluflturmad›¤› tespit edilmifltir. M + K in bu dozlarda uygulanmas› ile 15-60 dakika aras›nda devam eden güvenilir ve derin bir anestezi elde edilebilir. 

The applications of medetomidine (M) as a pre-anaesthetic and ketamine (K) as an anaesthetic agent were investigated in seven domestic pigeons in terms of the degree of anaesthesia (DA) and alterations in physiological parameters. An intramuscular (IM) injection of M (200 µg/kg) was followed by administration of K (120 mg/kg, IM) after 10 min. Body temperature (BT), respiratory rate (RR), heart rate (HR), DA, and electrocardiogram (ECG) findings were determined before (0 min) and 10 min after the application of M, and 5, 15, 30, 45 and 60 min after the administration of K. All pigeons had 4th degree anaesthesia and a significant decrease (p < 0.01) in HR was observed starting from the 10th min and lasting until the end of the anaeasthesia period. RR was significantly decreased at the 10th min of pre-anaesthesia (p < 0.01). Following K application, RR increased at the 5th min and stayed high until the 30th min, but decreased again afterwards. HR decreased dramatically during pre-anaesthesia (p < 0.01) and gradually during anaesthesia (p < 0.05). An obvious prolongation of P-R and R-R intervals was the only ECG finding. It was observed that BT constantly decreased during pre-anaesthesia and anaesthesia (p < 0.05 or p < 0.001). In conclusion, it was found that M + K combination anaesthesia caused alterations in the physiological parameters in pigeons, but they did not possess a life threatening effect. The application of M + K at these dose levels might produce a reliable and deep anaesthesia lasting 15 to 60 min.