Endometritis in Simmental cows: incidence, causes, and therapy options

The objectives of this study were to evaluate endometritis incidence and possible causes, and to assess the different therapy options. From a total of 1300 cows, endometritis was diagnosed in 23.07%, with clinical endometritis in 15.31% and subclinical endometritis in 7.77%. Previous dystocia resulted in 40.59% of the clinical endometritis and 47.52% of the subclinical endometritis (P < 0.05). Placental retention caused clinical and subclinical endometritis in 43.18% and 37.50% of the cows, respectively (P < 0.05). Body condition score 2 resulted in the highest endometritis rate and body condition score 3-4 resulted in the lowest endometritis rate (P < 0.05). Corpus luteum was found in 9.67% of the cows suffering from endometritis, while the rest developed various types of subfertility (P < 0.05). Three groups of cows (A, B, and C) with an almost equal number of clinical and subclinical endometritis diagnoses were formed. All of the groups received prostaglandin analogues (PGF Veyx Forte®, Veyx Pharma) intramuscularly 3 times at 11 day intervals. In group A, only prostaglandins were used; in group B, cephapirin (Metricure®, Intervet Schering-Plough) was administered into the corpus uteri simultaneously with the first 2 doses of prostaglandins; and in group C, the first 2 doses of prostaglandins were followed by the ozone product Riger Spray&#61666; (Novagen, Italy) applied into the uterus. The criteria applied for the therapy success were the number of cows conceived after the first artificial insemination and the number of days open. The best therapy results were achieved in groups C and B (P < 0.05), with the advantage of no milk and meat withdrawing period in the animals of group C.

Endometritis in Simmental cows: incidence, causes, and therapy options

The objectives of this study were to evaluate endometritis incidence and possible causes, and to assess the different therapy options. From a total of 1300 cows, endometritis was diagnosed in 23.07%, with clinical endometritis in 15.31% and subclinical endometritis in 7.77%. Previous dystocia resulted in 40.59% of the clinical endometritis and 47.52% of the subclinical endometritis (P < 0.05). Placental retention caused clinical and subclinical endometritis in 43.18% and 37.50% of the cows, respectively (P < 0.05). Body condition score 2 resulted in the highest endometritis rate and body condition score 3-4 resulted in the lowest endometritis rate (P < 0.05). Corpus luteum was found in 9.67% of the cows suffering from endometritis, while the rest developed various types of subfertility (P < 0.05). Three groups of cows (A, B, and C) with an almost equal number of clinical and subclinical endometritis diagnoses were formed. All of the groups received prostaglandin analogues (PGF Veyx Forte®, Veyx Pharma) intramuscularly 3 times at 11 day intervals. In group A, only prostaglandins were used; in group B, cephapirin (Metricure®, Intervet Schering-Plough) was administered into the corpus uteri simultaneously with the first 2 doses of prostaglandins; and in group C, the first 2 doses of prostaglandins were followed by the ozone product Riger Spray&#61666; (Novagen, Italy) applied into the uterus. The criteria applied for the therapy success were the number of cows conceived after the first artificial insemination and the number of days open. The best therapy results were achieved in groups C and B (P < 0.05), with the advantage of no milk and meat withdrawing period in the animals of group C.

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  • Parkinson, T.J.: Infertility. In: Noakes, D.E., Parkinson, T.J., England, G.C.W., Eds. Arthur’s Veterinary Reproduction and Obstetrics. 8th edn., W.B. Saunders Co., Philadelphia. 2001; 463–464.
  • LeBlanc, S.J., Duffield, T.F., Leslie, K.E., Bateman, K.G., Keefe, G.P., Walton, J.S., Johnson, W.H.: Defining and diagnosing postpartum clinical endometritis and its impact on reproductive performance in dairy cows. J. Dairy Sci., 2000; 285: 2223–2236.
  • Lewis, G.S.: Health problems of the postpartum cow, uterine health and disorders. J. Dairy Sci., 1997; 80: 984–994.
  • Bonnett, B.N., Martin, S.W., Meek, A.H.: Associations of clinical findings, bacteriological and histological results of endometrial biopsy with reproductive performance of postpartum dairy cows. Prev. Vet. Med., 1993; 15: 205–220.
  • Bretzlaff, K.N.: Rationale for treatment of endometritis in the dairy cow. Vet. Clin. North Am. Food Anim. Pract., 1987; 3: 593–607.
  • Kasimanickam, R., Duffield, T.F., Foster, R.A., Gartley, C.J., Leslie, K.E., Walton, J.S., Johnson, W.H.: Endometrial cytology and ultrasonography for the detection of subclinical endometritis in postpartum dairy cows. Theriogenology, 2004; 62: 9–23.
  • Bruun, J., Ersbİll, A.K., Alban, L.: Risk factors for metritis in Danish dairy cows. Prev. Vet. Med., 2002; 54: 179–190.
  • Sheldon, I.M., Noakes, D.E., Rycroft, A.N., Pfeiffer, D.U., Dobson, H.: Influence of uterine bacterial contamination after parturition on ovarian dominant follicle selection and follicle growth and function in cattle. Reproduction, 2002; 123: 837– 8
  • Opsomer, G., Gröhn, Y.T., Hertl, J., Coryn, M., Deluyker, H., de Kruif, A.: Risk factors for postpartum ovarian dysfunction in high producing dairy cows in Belgium: a field study. Theriogenology, 2000; 53: 841–857.
  • LeBlanc, S.J., Duffield, T.F., Leslie, K.E., Bateman, K.G., Keefe, G.P., Walton, J.S., Johnson, W.H.: The effect of treatment of clinical endometritis on reproductive performance in dairy cows. J. Diary Sci., 2002; 85: 2237–2249.
  • Kasimanickam, R., Duffield, T.F., Foster, R.A., Gartley, C.J., Leslie, K.E., Walton, J.S., Johnson, W.H.: The effect of a single administration of cephapirin or cloprostenol on the reproductive performance of dairy cows with subclinical endometritis. Theriogenology, 2005; 63: 818–830.
  • Heuwieser, W., Tenhagen, B.A., Tischer, M., Lühr, J., Blum, H.: Effect of three programmes for the treatment of endometritis on the reproductive performance of a dairy herd. Vet. Rec., 2000; 146: 338–341.
  • Adams, H.R.: Veterinary Pharmacology and Therapeutic. 8th edn., Iowa State University Press, Ames, IA, USA. 2001: 822– 8
  • Silva, R.A., Garotti, J.E.G., Silva, R.S., Navarini, A., Pacheco, A. Jr: Analysis of the bactericidal effect of ozone pneumoperitoneum. Acta Cir. Bras., 2009; 24: 124–127.
  • Bocci, V.: Ozone as bioregulator. Pharmacology and toxicology of ozone therapy today. J. Biol. Regul. Homeost. Agents, 1996; 10: 31–53.
  • Zimran, A., Wasser, G., Forman, L., Gelbart, T., Beutler, E.: Effect of ozone on red blood cell enzymes and intermediates. Acta Haematol., 2000; 102: 148–152.
  • Gretchkanev, O.G., Katchalina, T.S., Katchalina, O.V., Husein, H.: The new method of treatment of inflammatory diseases of lower female genital organs. Congreso Mundial Ozono Londres, 2001.
  • Ogata, A., Nagahata, H.: Intramammary application of ozone therapy to acute clinical mastitis in dairy cows. J. Vet. Med. Sci., 2000; 62: 681–686.
  • Watson, E.D., Harwood, D.J.: Clinical and endocrinological investigation of possible ovulatory failure in a dairy cow. Vet. Rec., 1984; 114: 424–425.
  • Hanzen, C.H., Bascon, F., Theron, L., Lopez-Gatius, F.: Les kystes ovariens dans l’espèce bovine 1. Définitions, symptômes et diagnostic [Ovarian cysts in cattle. Definitions, symptoms and diagnosis]. Ann. Med. Vet., 2007; 151: 247–256.
  • Peter, A.T.: Infertility due to abnormalities of the ovaries. In: Current Therapy in Large Animal Theriogenology. Youngquist, R.S., Ed. WB Saunders Co., Philadelphia. 1997; 349–354.
  • Edmonson, A., Lean, I.J., Weaver, L.D., Farver, T., Webster, G.: A body condition scoring chart for Holstein dairy cows. J. Dairy Sci., 1989; 72: 68–78.
  • Gautam, G., Nakao, T., Yusuf, M., Koike, K.: Prevalence of endometritis during the postpartum period and its impact on subsequent reproductive performance in two Japanese dairy herds. Anim. Reprod. Sci., 2009; 116: 175–187.
  • Markusfeld, O.: Periparturient traits in seven high dairy herds. Incidence rates, association with parity, and interrelationship among traits. J. Dairy Sci., 1987; 70: 158–168.
  • Kim, I.H., Kang, H.G.: Risk factors for postpartum endometritis and the effect of endometritis on reproductive performance in dairy cows in Korea. J. Reprod. Dev., 2003; 49: 485–491.
  • Gröhn, Y.T., Erb, H.N., McCulloch, C.E., Saloniemi, H.S.: Epidemiology of reproductive disorders in dairy cattle: associations among host characteristics, disease and production. Prev. Vet. Med., 1990; 8: 25–39.
  • Hendricks, K.E.M., Bartolome, J.A., Melendez, P., Risco, C., Archbald, L.F.: Effect of repeated administration of PGF2a in the early post partum period on the prevalence of clinical endometritis and probability of pregnancy at first insemination in lactating dairy cows. Theriogenology, 2006; 65: 1454–1464.
  • Jakab, G.J., Spannhake, E.W., Canning, B.J., Kleeberger, S.R., Gilmour, M.I.: The effects of ozone on immune function. Environ. Health Perspect., 1995; 103: 77–89.
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

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First detection and molecular identification of Babesia gibsoni in two dogs from the Aydın Province of Turkey

Nuran AYSUL, Kerem URAL, Bülent ULUTAŞ, Hasan EREN, Tülin KARAGENÇ

Endometritis in Simmental cows: incidence, causes, and therapy options

Robert ZOBEL

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