Dicephalus, Arnold-Chiari malformation, spinal dysraphism and other associated anomalies in a newborn Holstein calf

Bu çalışmada yeni doğan Holstein bir buzağıda disefalus, Arnold-Chiari malformasyonu, spinal disrafizm ve diğer malformasyonlar belirlendi. Buzağıdaki her iki kafa medial ve kaudal olarak temporal kemikler ile yassılaşmış bir adet oksipital kemik aracılığı ile birleşmişti. Kranial boşluklar dorsoventral olarak daralmıştı ve bu nedenle her iki beyinin basınca uğradığı ve serebellumların hipoplazik durumda kaudale doğru yer değiştirdiği gözlendi. Medulla spinaliste değişen derecelerde hidromiyeli ve siringomiyeli ile birlikte serviko-torakal diplomiyeli ve lumbar spinal agenezisli spina bifida gözlendi. Buzağıda arka bacaklarda artrogripozis ve her iki kafada damak yarığı mevcuttu.

Yeni doğan Holstein buzağıda disefalus, Arnold-Chiari malformasyonu, spinal disrafizm ve ilgili diğer anomaliler

A case of dicephalus, Arnold-Chiari malformation, spinal dysraphism and other associated defects was described in a newborn Holstein calf. The heads were medially and caudallyjoined with temporal bones and one common flattened occipital bone respectively. Cranial cavities became narrow dorsoventrally and included elongation of the compressed brains, and caudal displacement and hypoplasia of cerebelli. In the spinal column, variable degrees of dysraphism such as cervico-thoracal diplomyelia with hydromyelia and syringomyelia, lumbar spina bifida with spinal cord agenesis in the region were observed. The calf had also arthrogryposis of hind limbs and deft palate of both heads.

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1. Jenkins, T.W., Hardy, P.H.: Diprosopus and related cephalic malformations in a calf. Anat. Rec, 1968; 160: 161-170.
2. Hiraga, T., Abe, ML, Iwasa, K., Takehana, K.: Anatomical investigation of 39 cases of congenital duplication in calves. Cong. Anom., 1989; 29: 139-149.
3. Boyd, J.S.: Unusual case of spina bifida in a Friesian cross calf. Vet. Rec, 1985; 116: 203-205.
4. Cho, D.Y., Leipold, H.W.: Arnold-Chiari malformation and associated anomalies in calves. Acta Neuropatol. (Berl.), 1977; 39: 129-133.
5. Cho, D.Y., Leipold, H.W.: Congenital defects of the bovine nervous system. Vet. Bull., 1977; 47: 489-504.
6. Hiraga, T., Abe, M.: Two calves of Arnold-Chiari malformation and their craniums. Jpn. J. Vet. Sci., 1987; 49: 651-656.
7. LeClerc S., Lopez, A., Illanes, 0.: Central nervous system and vertebral malformation resembling the Arnold-Chiari syndrome in a Simmental calf. Can. Vet. J., 1997; 38: 300-301.
8. Madarame, H., Azuma, K., Nozuki, H., Konno, S.: Cerebellar hypoplasia associated with Arnold-Chiari malformation in a Japanase Shorthorn calf. J. Comp. Pathol., 1991; 104: 1-5.
9. Ohfuji, S.: Spinal dysraphism in a newborn Holstein-Friesian calf. Vet. Pathol., 1999; 36: 607-609.
10. Milli, Ü.H., Hazıroğlu, R.M., Hazıroğlu, R.: Bir buzağıda artrogripozis, dudak-damak yarığı, kalp defektleri ve diğer malformasyonlar. Ankara Üniv. Vet. Fak. Derg., 1988; 35: 246-252.
11. Gruys, E.: Dicephalus, spina bifida, Arnold-Chiari malformation and duplication of thoracic organs in a calf. J. Vet. Med. A., 1973; 20: 789-800.
12. Madarame, H., Takai, S., Ito, N.: Two headed, two necked conjoined twin calf with Arnold-Chiari malformation in a Japanese Shorthorn calf. Anat. Histol. Embryol., 1994; 23: 275-280.
13. Madarame, H., Ito, N., Takai, S.: Dicephalus, Arnold-Chiari malformation and spina bifida in a Japanese black calf. J. Vet. Med. A...J993; 40: 155-160.
14. Wakuri, H., Mori, T., Mutoh, K.: Arnold-Chiari malformation and associated anomalies in a dicephalic newborn calf. Okajimas Folia Anat. Jpn., 1990; 67: 339-350. 15. Summers, B.A., Cummings, J.F., de Lahunta, A.: Malformations of the central nervous system. In: Summers, B.A., Cummings, J.F., de Lahunta, A., Eds. Veterinary Neuropathology. St Louis, Mosby-Year Book, 1994; 68-94. 16. Tortori-Donati, P., Rossi, A., Cama, A.: Spinal dysraphism: a review of neuroradiological features with embryological correlations and proposal for a new classification. Neuroradiology, 2000; 42: 471-491. 17. Kruyff, E., Jeffs, R.: Skull abnormalities associated with the Arnold-Chiari malformation. Acta Radiol., 1966; 5: 9-24. 18. Marin-Padilla, M., Marin-Padilla, T.M.: Morphogenesis of experimentally induced Arnold-Chiari malformation. J. Neuorol. Sci., 1981:50:29-55.