Böbrek hastalıklı köpeklerde antioksidatif metabolizma

Kidney diseases and antioxidateve metabolism in dogs

The aim of this study was to investigate the role of free radicals and to show the changes in the antioxidative metabolism of dogs with renal diseases. For this purpose, the plasma malonlydialdehyde levels, activities of the GSH-Px, SOD and CAT in hemolysates of the red cells, and serum and plasma levels of the b-carotene and ascorbic acid were analysed to determine their relationships. A total of 35 dogs aged between 3 and 5 years were used. Twenty healthy dogs with no clinical signs comprised the as control group. Clinically, fifteen dogs exhibited kidney disorders and this diagnosis was supported by laboratory measurements of serum total protein, urea and creatinine levels in the trial group. Serum total protein levels were decreased (p

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