Biocompatibility of high-density porous polyethylene covered with fascia lata in dorsal nasal augmentation-an experimental study in rabbits

Ten New Zealand Albino rabbits were used in this study. A lateral incision was made on the nasal dorsum and a pocket formed in the subperiosteal plane to replace the implant. A fascia lata graft was obtained from the regio femoralis. High-density porous polyethylene (HDPP) was cut and covered with fascia lata. The material was positioned in the pocket formed on the nasal dorsum. Four months post-procedure, magnetic resonance imaging (MRI) was performed to evaluate the resorption of the material. Animals were then sacrificed and the nasal dorsum, including the graft material, was removed and subjected to macroscopic and histopathological examinations. All rabbits survived the 4-month period. MRI revealed that all the graft materials were intact; no sign of resorption was evident. Macroscopically, no rejection was observed. Histopathologic examination revealed that the HDPP remained intact on the nasal dorsum. HDPP covered with fascia can therefore be used for augmentation of the nasal dorsum. HDDP is easy to work with and will avoid the increased operative time and morbidity associated with autograft harvesting.

Biocompatibility of high-density porous polyethylene covered with fascia lata in dorsal nasal augmentation-an experimental study in rabbits

Ten New Zealand Albino rabbits were used in this study. A lateral incision was made on the nasal dorsum and a pocket formed in the subperiosteal plane to replace the implant. A fascia lata graft was obtained from the regio femoralis. High-density porous polyethylene (HDPP) was cut and covered with fascia lata. The material was positioned in the pocket formed on the nasal dorsum. Four months post-procedure, magnetic resonance imaging (MRI) was performed to evaluate the resorption of the material. Animals were then sacrificed and the nasal dorsum, including the graft material, was removed and subjected to macroscopic and histopathological examinations. All rabbits survived the 4-month period. MRI revealed that all the graft materials were intact; no sign of resorption was evident. Macroscopically, no rejection was observed. Histopathologic examination revealed that the HDPP remained intact on the nasal dorsum. HDPP covered with fascia can therefore be used for augmentation of the nasal dorsum. HDDP is easy to work with and will avoid the increased operative time and morbidity associated with autograft harvesting.

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  • Chen, C.T., Hu, T.L., Lai, J.B., Chen, Y.C., Chen, Y.R.: Reconstruction of traumatic nasal deformity in Orientals. J. Plast. Reconstr. Aesthet. Surg., 2010; 63: 257–264.
  • Staffel, G., Shockley, W.: Nasal implants. Otolaryngol. Clin. North. Am., 1995; 28: 295–308.
  • Jang, Y.J., Yu, M.S.: Rhinoplasty for the Asian nose. Facial Plast. Surg., 2010; 26: 93–101.
  • Emsen, I.M.: E-M shaped septal encircling with Medpor reconstruction on crooked noses: personal technique and postoperative results. J. Craniofac. Surg., 2008; 19: 216–26.
  • Hong, J.P., Yoon, J.Y., Choi, J.W.: Are polytetrafluoroethylene (Gore-Tex) implants an alternative material for nasal dorsal augmentation in Asians? J. Craniofac. Surg., 2010; 21: 1750– 17
  • Wellisz, T.: Clinical experience with the Medpor porous polyethylene implant. Aesthetic. Plast. Surg., 1993; 17: 339–44.
  • Oliveira, R.V., de Souza Nunes, L.S., Filho, H.N., de Andrade Holgado, L., Ribeiro, DA., Matsumoto, M.A: Fibrovascularization and osteogenesis in high-density porous polyethylene implants. J. Craniofac. Surg., 2009; 20: 1120–1124.
  • Seyhan, T., Kircelli, B.H., Caglar, B.: Correction of septal and midface hypoplasia in maxillonasal dysplasia (Binder’s syndrome) using high-density porous polyethylene. Aesthetic. Plast. Surg., 2009; 33: 661–665.
  • Baj, A., Spotti, S., Marelli, S., Beltramini, G.A., Giannì, A.B.: Use of porous polyethylene for correcting defects of temporal region following transposition of temporalis myofascial flap. Acta Otorhinolaryngol. Ital., 2009; 29: 265–269.
  • Keefe, M.S., Keefe, M.A.: An evaluation of the effectiveness of different techniques for intraoperative infiltration of antibiotics into alloplastic implants for use in facial reconstruction. Arch. Facial Plast. Surg., 2009; 11: 246–251.
  • Yildirim, G., Haliloglu, T., Sapçi, T., Kahvecioglu, O., Onar, V., Savci, N., Karavus, A.: Tracheal reconstruction with porous high-density polyethylene tracheal prosthesis. Ann. Otol. Rhinol. Laryngol., 2000; 109: 981–987.
  • Tsai, F.C., Liao, C.K., Fong, T.H., Lin, J.Y., Wu, S.T.: Analysis of nasal periosteum and nasofrontal suture with clinical implications for dorsal nasal augmentation. Plast. Reconstr. Surg., 2010; 126: 1037–1047.
  • Turegun, M., Acarturk, T.O., Ozturk, S., Sengezer, M.: Aesthetic and functional restoration using dorsal saddle shaped Medpor implant in secondary rhinoplasty. Ann. Plast. Surg., 2008; 60: 600–603.
  • Reiffel, A.J., Cross, K.J., Spinelli, H.M.: Nasal spreader grafts: a comparison of medpor to autologous tissue reconstruction. Ann. Plast. Surg., 2011; 66: 24–28.
  • Godin, M.S., Waldman, S.R., Johnson, C.M. Jr: Nasal augmentation using Gore-Tex. A 10-year experience. Arch. Facial Plast. Surg., 1999; 1: 118–121.
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK