Effective use of probiotic-glyconutrient combination as an adjuvant to antibiotic therapy for diarrhea in rearing dairy calves

Thirty Holstein calves presented with infectious diarrhea during the second week following birth were utilized to evaluate the effects of a standardized product containing a combination of probiotics, ß-glucans, and glyconutrients (GLY) in support of antibiotic therapy during the early rearing phase (day 7 to day 45 following birth). Treatments were 1) antibiotic therapy (trimethoprim and sulfas; ANTIB), and 2) ANTIB plus 5 g/calf per day GLY. Treatments did not affect diarrhea duration, averaging 16.7 days. However, GLY support decreased (P < 0.05) the mortality rate and increased (P < 0.05) live weight gain. Increased weight gain was attributable to enhanced (P < 0.05) consumption of calf starter. Supplemental GLY increased (P < 0.05) serum glucose and lowered (P < 0.05) serum urea nitrogen, nonesterified fatty acids, and cortisol concentration. We conclude that daily provision of 5 g of a standardized product containing probiotics, ß-glucans, and glyconutrients to diarrheic calves under antibiotic therapy will promote health and enhance early growth performance.

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  • Pijoan P. Management factors associated with calf mortality in dairy farms of Tijuana, Baja California, Mexico. Vet Méx 1997; 28: 269-275.
  • Guyton A, Hall J. Textbook of Medical Physiology. Philadelphia; PA, USA: Elsevier, Mosby Saunders; 2006. pp. 819-825.
  • Uyeno Y, Shigemori S, Shimosato T. Effects of prebiotics/ prebiotics in cattle health and productivity: mini-review. Microbes Environ 2015; 30: 126-132.
  • Yirga H. The use of probiotics in animal nutrition. Prob Health 2015; 3: 2.
  • Murray RK. Glycoproteins. In: Murray RK, Granner DK, Rodwell VW, editors. Harpers Illustrated Biochemistry. 27th ed. Columbus, OH, USA. McGraw-Hill; 2006, pp. 523-544.
  • Schnaar RL, Freeze HH. A “glyconutrient sham”. Glycobiology 2008; 18: 652-657.
  • National Research Council. Nutrient Requirements of Dairy Cattle, 7th edn. Washington, DC, USA: National Academy Press; 2001.
  • Abeni F, Bergoglio G, Masoero G, Tarzano GM, Allegrini S. Plasma hormones and metabolites in Piedmontese cows during late pregnancy: relationships with calf birth weight. J Anim Sci 2004; 82: 438-444.
  • AOAC. Official Methods of Analysis. 17th ed. Arlington, VA, USA: Association of Official Analytical Chemists; 2000.
  • Statistical Analysis System. SAS/STAT: User’s Guide Statistic Released 9.1. Cary, NC, USA: SAS Institute Inc; 2004.
  • Morrill JL, Morrill JM, Feyerherm AM, Laster J.F. Plasma proteins and probiotic as ingredients in milk replacer. J Dairy Sci 1995; 78: 902-907.
  • Qadis AQ, Goya S, Yatsu M, Kimura A, Ichijo T, Sato S. Immune-stimulatory effects of a bacteria-based probiotic on peripheral leukocyte subpopulations and cytokine mRNA expression levels in scouring Holstein calves. J Vet Med Sci 2014; 76: 677-684.
  • Quigley III JD, Bernard JK, Tyberendt TL, Martin KR. Intake, growth, and selected blood parameters in calves fed starter via bucket or bottle. J Dairy Sci 1994; 77: 354-357.
  • Mohri M, Sharifi K, Eide S. Hematology and serum biochemistry of Holstein dairy calves: age related change and comparison with blood composition in adults. Res Vet Sci 2007; 83: 30-39.
  • Piccione G, Casella S, Pennisi P, Giannetto C, Costa A, Caola G. Monitoring of physiological and blood parameters during perinatal and neonatal period in calves. Arq Bras Vet Zootec 2010; 62: 1-12.
  • Sasaki O, Yamamoto N, Togashi K, Minezawa M. Effects of age, environments and sex on plasma metabolite levels in young Holstein calves. Asian-Aust J Anim Sci 2002; 15: 637-642.
  • Sundrum A. Metabolic disorders in the transition period indicate that the dairy cows’ ability to adapt is overstressed. Animal (Basel) 2015; 5: 978-1020.
  • Schwartzkopf-Genswein KS, Booth-McLean ME, McAllister TA, Mears GJ. Physiological and behavioural changes in Holstein calves during and after dehorning or castration. Can Anim Sci 85: 131-138.
Turkish Journal of Veterinary and Animal Sciences-Cover
  • ISSN: 1300-0128
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
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