Oral health status of asthmatic children using inhaled corticosteroids

Background. Due to the increase in the prevalence of asthma, especially in childhood, oral health problems arising from the use of asthma medications have become a major health concern. Inhaled corticosteroids are widely used since they are the cornerstone of asthma management. This study aimed to investigate the effects of inhaled corticosteroids on oral health and various factors regarding active ingredients in inhalers, inhaler-spacer device use, rinsing the mouth after administration of inhaler, oral hygiene practices and parents’ education on dental caries susceptibility in young children with asthma. Methods. Children with asthma who were treated with inhaled corticosteroids for at least 6 months were included in the study. A questionnaire related to demographic characteristics and oral health practices of children was conducted with parents and the children were examined using a dental mirror and probe under dental unit lighting after air-drying the teeth. Results. Oral health status was evaluated in 115 children, 54 (42-66) months old, 61% male and 39% female with determination of dmft-dmfs, DMFT-DMFS, ICDAS II, plaque index and gingival index. No statistically significant difference was found between sugar-containing and sugar-free inhalers, duration of inhaled corticosteroid use, inhaler-spacer device use, rinsing the mouth after administration of inhaler and dmft-dmfs, DMFT-DMFS, plaque and gingival index (p>0.05). Long-term inhaled corticosteroid use was significantly associated with oral candidiasis (p=0.029). Also, the results showed that mothers’ educational level had a significant effect on children’s oral health (pdmft/dmfs

___

1. Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008; 31: 143-178.

2. Steinbacher DM, Glick M. The dental patient with asthma: an update and oral health considerations. J Am Dent Assoc 2001; 132: 1229-1239.

3. Stensson M, Wendt LK, Koch G, Oldaeus G, Birkhed D. Oral health in preschool children with asthma. Int J Paediatr Dent 2008; 18: 243-250.

4. Eloot AK, Vanobbergen JN, De Baets F, Martens LC. Oral health and habits in children with asthma related to severity and duration of condition. Eur J Paediatr Dent 2004; 5: 210-215.

5. Brigic A, Kobaslija S, Zukanovic A. Antiasthmatic inhaled medications as favoring factors for increased concentration of streptococcus mutans. Mater Sociomed 2015; 27: 237-240.

6. Lindemeyer RG, Satpute NS, Katz SH. Evaluation of bronchial asthma as risk factor for early childhood caries. J Mich Dent Assoc 2012; 94: 46-49.

7. Tootla R, Toumba KJ, Duggal MS. An evaluation of the acidogenic potential of asthma inhalers. Arch Oral Biol 2004; 49: 275-283.

8. Hyyppä TM, Koivikko A, Paunio KU. Studies on periodontal conditions in asthmatic children. Acta Odontol Scand 1979; 37: 15-20.

9. Ellepola AN, Samaranayake LP. Inhalational and topical steroids, and oral candidosis: a mini review. Oral Dis 2001; 7: 211-216.

10. World Health Organization. Oral Health Surveys Basic Methods. Geneva: WHO Press, 2013: 47-74.

11. Ismail AI, Sohn W, Tellez M, et al. The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries. Community Dent Oral Epidemiol 2007; 35: 170-178.

12. Silness J, Löe H. Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964; 22: 121-135.

13. Löe H. The gingival index, the plaque index and the retention index systems. J Periodontol 1967; 38(Suppl): 610-616.

14. Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. 2017: 29. (Available from: http://www.ginasthma.org/).

15. Shashikiran ND, Reddy VVS, Raju PK. Effect of antiasthmatic medication on dental disease: dental caries and periodontal disease. J Indian Soc Pedod Prev Dent 2007; 25: 65-68.

16. Blumenshine SL, Vann Jr WF, Gizlice Z, Lee JY. Children’s school performance: impact of general and oral health. J Public Health Dent 2008; 68: 82-87.

17. Pitts N. ICDAS-an international system for caries detection and assessment being developed to facilitate caries epidemiology, research and appropriate clinical management. Community Dent Health 2004; 21: 193-198.

18. Shulman JD, Taylor SE, Nunn ME. The association between asthma and dental caries in children and adolescents: a population–based case–control study. Caries Res 2001; 35: 240-246.

19. Meldrum AM, Thomson WM, Drummond BK, Sears MR. Is asthma a risk factor for dental caries? Findings from a cohort study. Caries Res 2001; 35: 235-239.

20. Mazzoleni S, Stellini E, Cavaleri E, Angelova Volponi A, Ferro R, Fochesato Colombani S. Dental caries in children with asthma undergoing treatment with short-acting ß2-agonists. Eur J Paediatr Dent 2008; 9: 132-138.

21. Ballikaya E, Dogan BG, Onay O, Uzamıs Tekcicek M. Oral health status of children with mouth breathing due to adenotonsillar hypertrophy. Int J Pediatr Otorhinolaryngol 2018; 113: 11-15.

22. Khalilzadeh S, Salamzadeh J, Salem F, Salem K, Vala MH. Dental caries-associated microorganisms in asthmatic children. Tanaffos 2007; 6: 42-46.

23. Locker D. Measuring social inequality in dental health services research: individual, household and area-based measures. Community Dent Health 1993; 10: 139-150.

24. McDerra EJ, Pollard MA, Curzon ME. The dental status of asthmatic British school children. Pediatr Dent 1998; 20: 281-287.

25. Laurikainen K. Asthma and oral health: a clinical and epidemiological study. Acta Univ Tamperensis 2002. (Available from: https://trepo.tuni.fi/bitstream/ handle/10024/67473/951-44-5404-9.pdf?sequence=1)

26. Ersin NK, Guelen F, Eronat N, et al. Oral and dental manifestations of young asthmatics related to medication, severity and duration of condition. Pediatr Int 2006; 48: 549-554.

27. Mandel ID, Eriv A, Kutscher A, et al. Calcium and phosphorus levels in submaxillary saliva. Changes in cystic fibrosis and in asthma. Clin Pediatr (Phila) 1969; 8: 161-164.

28. Milano M, Lee JY, Donovan K, Chen JW. A crosssectional study of medication-related factors and caries experience in asthmatic children. Pediatr Dent 2006; 28: 415-419.

29. Lipworth BJ. Clinical pharmacology of corticosteroids in bronchial asthma. Pharmacol Ther 1993; 58: 173-209.

30. Enwonwu CO, Meeks VI, Sawiris PG. Elevated cortisol levels in whole saliva in HIV infected individuals. Eur J Oral Sci 1996; 104: 322-324.

31. Knight L, Fletcher J. Growth of Candida albicans in saliva: stimulation by glucose associated with antibiotics, corticosteroids, and diabetes mellitus. J Infect Dis 1971; 123: 371-377.

32. Samaranayake LP, MacFarlane TW. On the role of dietary carbohydrates in the pathogenesis of oral candidosis. FEMS Microbiol Lett 1985; 27: 1-5.

33. Kuna P. Longterm effects of steroid therapy. Wiad Lek 1998; 51(Suppl 1): 12-18.

34. Ogueta IC, Ramírez MP, Jiménez CO, Cifuentes MM. Geographic tongue: what a dermatologist should know. Actas Dermosifiliogr 2019; 110: 341-346.

35. McDowell JD, Kassebaum DK. Diagnosing and treating halitosis. J Am Dent Assoc 1993; 124: 55-64.

36. Motta LJ, Bachiega JC, Guedes CC, Laranja LT, Bussadori SK. Association between halitosis and mouth breathing in children. Clinics (Sao Paulo) 2011; 66: 939-942
Turkish Journal of Pediatrics-Cover
  • ISSN: 0041-4301
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 1958
  • Yayıncı: Hacettepe Üniversitesi Çocuk Sağlığı Enstitüsü Müdürlüğü
Sayıdaki Diğer Makaleler

Practice, self-confidence and understanding of pediatric obstructive sleep apnea survey among pediatricians

Kantara SAELIM, Monthida UTHAIRAT, Kanokpan RUANGNAPA, Pharsai PRASERTSAN, Wanaporn ANUNTASEREE

Mucormycosis in a pediatric population: a review of 20 cases from southern Turkey

Derya ALABAZ, Gülsüm YILMAZ, Aysun UĞUZ, Süleyman ÖZDEMİR, Hatice Ilgen ŞAŞMAZ, İbrahim BAYRAM

Ophthalmologic approach to babies with cerebral visual impairment

Aysun İDİL, Deniz ALTINBAY, ESRA ŞAHLI, Pınar Bingöl KIZILTUNÇ, Hatice Semrin Timlioğlu İPER, Kadriye ERKAN TURAN, Damla ERGİNTÜRK ACAR, Fatma Merve BEKTAŞ

Comparison of four different non-invasive respiratory support techniques as primary respiratory support in preterm infants

Ahmet ÖKTEM, Şule YİĞİT, HASAN TOLGA ÇELİK, Murat YURDAKOK

Brachial plexopathy as a consequence of nerve root swelling after shoulder trauma in a patient following an acute seizure

Filip MİLANOVİĆ, Dusan ABRAMOVIC, Sinisa DUCIC, Bojan BUKVA, Ivana DASIC, Tijana RADOVIC, Aline Choueiri PETERMANN MISKULIN, Dejan NIKOLIC

The HLA groups and their relationship with clinical features in Turkish children and adolescents with celiac disease

Necati Balamtekin, Gökhan BAYSOY, Nuray USLU KIZILKAN, Hulya DEMIR, İnci Nur SALTIK TEMİZEL, HASAN ÖZEN, Aysel YÜCE, Figen GÜRAKAN, ÇAĞMAN TAN, İlhan TEZCAN

Clinic and demographic characteristics of pediatric patients with Lichen sclerosus

Ayşe AKBAŞ, Fadime KILINÇ

Evaluation of micronutrient levels in children and adolescents with obesity and their correlation with the components of metabolic syndrome

Fatih KARDAŞ, Arife Derda YÜCEL, Mustafa KENDİRCİ, Selim KURTOĞLU, Nihal HATİPOĞLU, Leyla AKIN, Ülkü GÜL, Songül GÖKAY, Pembe ÜSTKOYUNCU

Fecal elastase levels in children diagnosed with functional abdominal pain-not otherwise specified

Burcu GÜVEN, Nuriye Burçin TURAN, Ahmet Fayik ÖNER, Kamuran KARAMAN, Mecnun ÇETİN

Evaluation of injury-related under-five mortality in Turkey between 2014-2017

Nilgün ÇAYLAN, Sıdıka Songül YALÇIN, Başak TEZEL, Şirin AYDIN, Önder ÖZEN, Meltem ŞENGELEN, Banu ÇAKIR