Kawasaki disease complicated by peripheral gangrene and a ventricular septal defect: An unusual association

Kawasaki disease is an acute febrile illness associated with the vasculitis ofsmall and medium size arteries. Peripheral gangrene is very rare but a knowncomplication of Kawasaki disease mostly reported in the infantile age group.Early therapy is advocated for prevention of serious complications. We reporta 10-month-old girl with Kawasaki disease and a small ventricular septaldefect who developed peripheral gangrene despite initiation of early therapy.

___

1. Ames EL, Jones JS, Van Dommelen B, Posch JL. Bilateral hand necrosis in Kawasaki syndrome. J Hand Surg Am 1985; 10: 391-395.

2. Belay ED, Maddox RA, Holman RC, Curns AT, Ballah K, Schonberger LB. Kawasaki syndrome and risk factors for coronary artery abnormalities: United States, 1994–2003. Pediatr Infect Dis J 2006; 25: 245-249.

3. Bonté I, Mahr A, Laroche L, Guillevin L, Robineau M. Peripheral gangrene in adult‐onset Kawasaki disease. Scand J Rheumatol 2005; 34: 71-73.

4. Brenner JL, Jadavji T, Pinto A, Trevenen C, Patton D. Severe Kawasaki disease in infants: two fatal cases. Can J Cardiol 2000; 16: 1017-1023.

5. Brogan PA, Bose A, Burgner D, et al. Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research. Arch Dis Child 2002; 86: 286-290.

6. Chang J-S, Lin J-S, Peng C-T, Tsai C-H. Kawasaki disease complicated by peripheral gangrene. Pediatr Cardiol 1999; 20: 139-142.

7. Dillon MJ, Eleftheriou D, Brogan PA. Medium-sizevessel vasculitis. Pediatr Nephrol 2010; 25: 1641-1652.

8. Durall AL, Phillips JR, Weisse ME, Mullett CJ. Infantile kawasaki disease and peripheral gangrene. Pediatr Crit Care Med 2004; 5: 511. (AAP Abstracts)

9. Gardner-Medwin JM, Dolezalova P, Cummins C, Southwood TR. Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet 2002; 360: 1197-1202.

10. Harnden A, Alves B, Sheikh A. Rising incidence of Kawasaki disease in England: analysis of hospital admission data. BMJ 2002; 324: 1424-1425.

11. Krohn C, Till H, Haraida S, et al. Multiple intestinal stenoses and peripheral gangrene: a combination of two rare surgical complications in a child with Kawasaki disease. J Pediatr Surg 2001; 36: 651-653.

12. Newburger JW, Takahashi M, Gerber MA, et al; Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease; Council on Cardiovascular Disease in the Young; American Heart Association; American Academy of Pediatrics. Diagnosis, treatment, and longterm management of Kawasaki disease. A statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation 2004; 110: 2747-2771.

13. Teixeira OH, Pong AH, Vlad P. Amputating gangrene in Kawasaki disease. Can Med Assoc J 1982; 127: 132-134.

14. Tomita S, Chung K, Mas M, Gidding S, Shulman ST. Peripheral gangrene associated with Kawasaki disease. Clin Infect Dis 1992; 14: 121-126.

15. Trumble T, Fitch RD. Kawasaki disease: A cause of vasculitis in children. J Pediatr Orthop 1986; 6: 92-95.

16. Westphalen MA, McGrath MA, Kelly W, Moore FJ, Ziegler JB. Kawasaki disease with severe peripheral ischemia: treatment with prostaglandin E1 infusion. J Pediatr 1988; 112: 431-433.

17. von Planta M, Fasnacht M, Holm C, Fanconi S, Seger R. Atypical Kawasaki disease with peripheral gangrene and myocardial infarction: therapeutic implications. Eur J Pediatr 1995; 154: 830-834.
Turkish Journal of Pediatrics-Cover
  • ISSN: 0041-4301
  • Yayın Aralığı: 6
  • Başlangıç: 1958
  • Yayıncı: Hacettepe Üniversitesi Çocuk Sağlığı Enstitüsü Müdürlüğü
Sayıdaki Diğer Makaleler

The impact of 21-hydroxylase deficiency on cardiac repolarization changes in children with 21-hydroxylasedeficient congenital adrenal hyperplasia

Hüseyin Anıl KORKMAZ, Rahmi ÖZDEMİR, Mehmet KÜÇÜK, Cem KARADENİZ, Timur MEŞE, Behzat ÖZKAN

An infant with an extremely rare cobalamin disorder: Methionine synthase deficiency and importance of early diagnosis and treatment

Çiğdem Seher KASAPKARA, Ebru Yılmaz KESKİN, Ferda Özbay HOŞNUT, Meltem AKÇABOY, Emine POLAT, Asburçe OLGAÇ, Pelin ZORLU

Kawasaki disease complicated by peripheral gangrene and a ventricular septal defect: An unusual association

Muhammad MOHSİN, Saleem AKHTAR

Noninvasive respiratory support via nasal cannula in premature infants: Is it really safe?

Mehmet BÜYÜKTİRYAKİ, Nilüfer OKUR, Gülsüm Kadıoğlu ŞİMŞEK, Hayriye Gözde KANMAZ, Fuat Emre CANPOLAT

Etiology of vaginal discharge in sexually inactive adolescents

Yasemin DÜZÇEKER, Sinem AKGÜL, Yasemin ÖZSÜREKÇİ, Orhan DERMAN, Ateş KARA, Nuray KANBUR

Tocilizumab treatment in juvenile idiopathic arthritis patients: A single center experience

Selcan DEMİR, Hafize Emine SÖNMEZ, Elif Arslanoğlu AYDIN, Seza ÖZEN, Yelda BİLGİNER

A novel de novo KCNQ2 mutation in a child with treatmentresistant early-onset epileptic encephalopathy

Christina BENETOU, Stavroula PAPAİLİOU, Despoina MARİTSİ, Katherine ANAGNOSTOPOULOU, Harry KONTOS, Georgios VARTZELİS

Giant axonal neuropathy: A differential diagnosis of consideration

Pınar EDEM, Mert KARAKAYA, Brunhilde WİRTH, Tuncay Derya OKUR, Uluç YİŞ

Self-introduced intravesical magnets in a 3-year-old boy: Case report

Tunç ÖZDEMİR, Gizem ORHAN, Belce CANDAN, Gökhan KÖYLÜOĞLU

Fetal intrapericardial teratomas

Shi Min YUAN, Hong LİN