Corticosteroid phobia among parents of asthmatic children

Corticosteroid phobia among parents of asthmatic children

Asthma is one of the most prevalent chronic diseases among children.Its prevalence and morbidity have been rising in recent decades. Pediatricasthma causes a significant burden on families; allergen-avoidance measures,uncontrolled disease, and disease severity which are the major cost predictorsof childhood asthma in Turkey. Inhaled corticosteroids (ICS) are consideredas cornerstone medications in asthma management which reduce asthmamorbidity and mortality. Our aim was to address corticosteroid phobia incaregivers of asthmatic children and its impact on asthma management.Five hundred caregivers of asthmatic children were interviewed using structuredquestionnaire in this study.Over fifty percent of the caregivers (56.8%), most of whom (82.6%) are alreadyaware of using corticosteroids in their anti-asthma drug regimen, mentionedthat they are afraid of using them. Almost one fourth of caregivers (24.8%)made either some changes in their treatment regimen or stopped using thedrugs due to corticophobia. Of the caregivers 55.2% had no idea about theside effects of corticosteroids and only 12.6% of them mentioned that theywere informed by their physicians about the effects of corticosteroids. Anychange in asthma treatment regimen due to corticophobia was found to berelated with poor asthma control level (p: 0.004).The impact of parental information about the effects and importance of steroidsgiven by the physicians on better asthma control was found to be highlysignificant (p

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  • 1. Global Initiative for Asthma (GINA) Program 2016. www.ginaasthma.org
  • 2. Bousquet J, Bousquet PJ, Godard P, Daures JP. The public health implications of asthma. Bull WHO 2005; 83: 548-554.
  • 3. Akcay A, Tamay Z, HocaogluAB, Ergin A, Guler N. Risk factors affecting asthma prevalence in adolescents living in Istanbul, Turkey. AllergolImmunopathol (Madr) 2014; 42: 449-458.
  • 4. Ones U, Akcay A, Tamay Z, Guler N, Zencir M. Rising trend of asthma prevalence among Turkish school children (ISAAC phases I and III). Allergy 2006; 61: 1448-1453.
  • 5. O’Byrne PM, Pedersen S, Schatz M, et al. The poorly explored impact of uncontrolled asthma. Chest 2013; 143: 511-523.
  • 6. Bateman ED, Reddel HK, Eriksson G, et al. Overall asthma control: the relationship between current control and future risk. J Allergy Clin Immunol 2010; 125: 600-608.
  • 7. Beyhun NE, Soyer OU, Kuyucu S, et al. A multi-center survey of childhood asthma in Turkey-I: The cost and its determinants. Pediatr Allergy Immunol 2009; 20: 72-80.
  • 8. Suissa S, Ernst P. Inhaled corticosteroids: impact on asthma morbidity and mortality. J Allergy Clin Immunol 2001; 107: 937-944.
  • 9. Rand CS. Non-adherence with asthma therapy: more than just forgetting. J Pediatr 2005; 146: 157-159.
  • 10. Brook U, Mendelberg A, Heim M. Increasing parental knowledge of asthma decreases the hospitalization of the child: A pilot study. J Asthma 1993; 30: 45-49.
  • 11. Cetinkaya F. Reasons for discontinuation of antiasthma drugs in children with asthma coming from lower socioeconomic classes in a developing country. Allergy Asthma Proc 2007; 28: 695-697.
  • 12. Rizzo MC, Solé D. Inhaled corticosteroids in the treatment of respiratory allergy: Safety vs. efficacy. J Pediatr (Rio J) 2006; 82(5 Suppl): S198-S205.
  • 13. Skoner JD, Schaffner TJ, Schad CA, Kwon AY, Skoner DP. Addressing steroid phobia: improving the riskbenefit ratio with new agents. Allergy Asthma Proc 2008; 29: 358-364.
  • 14. Egan JJ, Maden C, Kaira S, Adams JE, Eastell R, Woodcock AA. A randomized, double-blind study comparing the effects of beclomethasone and fluticasone on bone density over two years. Eur Respir J 1999; 13: 1267-1275.
  • 15. Tattersfield AE, Town GI, Johnell O, et al. Bone mineral density in subjects with mild asthma randomised to treatment with inhaled corticosteroids or noncorticotsteroid treatment for twoyears. Thorax 2001; 56: 272-278.
  • 16. Becker AB, Kuznetsova O, Vermeulen J, et al; Pediatric Montelukast Linear Growth Study Group. Lineargrowth in prepubertal asthmatic children treated with montelukast, beclomethasone, or placebo: A 56-week randomized double-blind study. Ann Allergy Asthma Immunol 2006; 96: 800-807.
  • 17. Simons FE. A comparison of beclomethasone, salmeterol, and placebo in children with asthma. Canadian Beclomethasone Dipropionate-Salmeterol Xinafoate Study Group. N Engl J Med 1997; 337: 1659-1665.
  • 18. Philip J. The effects of inhaled corticosteroids on growth in children. Open Respir Med J2014; 8(Suppl 1: M3): 66-73.
  • 19. Horne R, Weinman J. Patients’ beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res 1999; 47: 555- 567.
  • 20. Clifford S, Barber N, Horne R. Understanding different beliefs held by adherers, unintentional nonadherers, and intentional nonadherers: Application of the NecessityConcerns Framework. J Psychosom Res 2008; 64: 41-46.
  • 21. Yoos HL, Kitzman H, McMullen A. Barriers to antiinflammatory medication use in childhood asthma. Ambul Pediatr 2003; 3: 181-190.
  • 22. Menckeberg TT, Bouvy ML, Bracke M, et al. Beliefs about medicines predict refill adherence to inhaled corticosteroids. J Psychosom Res 2008; 64: 47-54.
  • 23. Conn KM, Halterman JS, Fisher SG, Yoos HL, Chin NP, Szilagyi PG. Parental beliefs about medications and medication adherence among urban children with asthma. Ambul Pediatr 2005; 5: 306-310.
  • 24. Peterson-Sweeney K, McMullen A, Yoos HL, Kitzman H. Parental perceptions of their child’s asthma: Management and medication use. J Pediatr Health Care 2003; 17: 118-125.
  • 25. Conn KM, Halterman JS, Lynch K, Cabana MD. The impact of parents’ medication beliefs on asthma management. Pediatrics 2007; 120: e521-e526.
  • 26. Gazala E, Sadka R, Bilenko NR. Parents’ fears and concerns toward inhaled corticosteroid treatment for their asthmatic children. Pediatr Asthma Allergy Immunol 2005; 18: 82-87.
  • 27. George M, Freedman TG, Norfleet AL, Feldman HI, Apter AJ. Qualitative research-enhanced understanding of patients’ beliefs: results of focus groups with lowincome, urban, African American adults with asthma. J Allergy Clin Immunol 2003; 111: 967-973.
  • 28. Farber HJ, Capra AM, Finkelstein JA, et al. Misunderstanding of asthma controller medications: association with nonadherence. J Asthma 2003; 40: 17-25.
  • 29. Zedan MM, Ezz El Regal M, A Osman E, E Fouda A. Steroid phobia among parents of asthmatic children: Myths and truth. Iran J Allergy Asthma Immunol 2010; 9: 163-168.
Turkish Journal of Pediatrics-Cover
  • ISSN: 0041-4301
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 1958
  • Yayıncı: Hacettepe Üniversitesi Çocuk Sağlığı Enstitüsü Müdürlüğü
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