Neslihan ÖNENLİ-MUNGAN, Ahmet YÖNTEM, Mehmet KARAKAŞ, Bircan HIZLI-KARABACAK, Deniz KÖR

Blue-colored sweating: four infants with apocrine chromhidrosis

Apocrine chromhidrosis is a very rare, idiopathic disorder of the sweat glandscharacterized by the secretion of colored sweat. Because hormonal inductionincreases sweating, the symptoms of apocrine chromhidrosis usually beginafter puberty. Although treatment may not be necessary in some cases,capsaicin cream and 20% aluminum chloride hexahydrate solution have beensuccessfully used to treat patients requiring intervention. Here we reportfour cases with apocrine chromhidrosis. To the best of our knowledge, ourpatients are the youngest cases reported in the literature.

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1. Fealey RD, Sato K. Disorders of the eccrine sweat glands and sweating. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Lefell DJ (eds). Fitzpatrick's Dermatology in General Medicine (7th ed) Vol. 1. New York, NY: McGraw-Hill; 2008: 720-730.
2. Chang YC, Anderson N, Soeprono F. Bilateral facial pigmentation. Dermatol Online J 2007; 13: 16.
3. Thami GP, Kanwar AJ. Red facial pseudochromhidrosis. Br J Dermatol 2000;142: 1219-1220.
4. Timani SS, Rubeiz N. Chromhidrosis. www.emedicine. com/derm/topic596.htm. Accessed June 9, 2004.
5. Allegue F, Hermo JA, Fachal C, Alfonsín N. Localized green pigmentation in a patient with hyperbilirubinemia. J Am Acad Dermatol 1996; 35: 108-109.
6. Albers SE, Brozena SJ, Glass FL, Fenske NA. Alkaptonuria and ochronosis: case report and review. J Am Acad Dermatol 1992; 27: 609-614.
7. Barankin B, Alanen K, Ting PT, Sapijaszko MJ. Bilateral facial apocrine chromhidrosis. J Drugs Dermatol 2004; 3: 184-186.
8. Pérez Tato B, Zamora Martínez E, Sánchez Albisua B, et al. Facial and axillary apocrine chromhidrosis. Dermatol Online J 2012; 18: 13.
9. Carman KB, Aydogdu SD, Sabuncu I, Yarar C, Yakut A, Ozlecan B. Infant with chromhidrosis. Pediatr Int 2011; 53: 283-284.
10. Griffith JR. Isolated areolar apocrine chromhidrosis. Pediatrics 2005; 115: e239-e241.
11. Marks JG Jr. Treatment of apocrine chromhidrosis with topical capsaicin. J Am Acad Dermatol 1989; 21: 418-420.
12. Saff DM, Owens R, Kahn TA. Apocrine chromhidrosis involving the areolae in a 15-year-old amateur figure skater. Pediatr Dermatol 1995; 12: 48-50.
13. Matarasso SL. Treatment of facial chromhidrosis with botulinum toxin type A. J Am Acad Dermatol 2005; 52: 89-91.
14. Wu JM, Mamelak AJ, Nussbaum R, McElgunn PS. Botulinum toxin A in the treatment of chromhidrosis. Dermatol Surg 2005; 31: 963-965.
15. Aoki T. Stimulation of human axillary apocrine sweat glands by cholinergic agents. J Invest Dermatol 1962; 38: 41-44.