Spectrum of clinical infectious diseases in hospitalized elderlypatients in the southeast of Iran

Amaç: Yaşlılar hücresel bağışıklıktaki azalma, kronik hastalıklar, kullanılan ilaçlar malnütrisyon ve fonksiyonel yetersizlikler nedeniyle bozulan defans mekanizmaları sonucunda infeksiyöz ajanlara karşı dayanıksızdır. Bu çalışma, hastaneye yatırılmış bir grup yaşlı hastada görülen enfeksiyöz hastalık tipi ve sıklığını saptamak için yapılmıştır. Yöntem ve Gereç: Bu kesitsel çalışma, Zahedan(Güneydoğu İran) daki hastanemize 2001-2006 yılları arasında yatırılan yaşlı hastalarda yapılmıştır. 1278 hastanın tanıları, risk faktörleri, tedavi seçenekleri, morbidite ve mortalite oranları retrospektif olarak araştırılmıştır. Bulgular: Tüberküloz(TB) en sık görülen enfeksiyon olup (%46) onu pömoni (%14.9), bronşit (%13), gastroenterit (%6.5) ve sepsis (%3.9) izlemiştir. TB olgularının çoğu (%98.2) akciğer tüberkülozudur. En az görülen enfeksiyon pulmoner aspergillozis olup sadece bir olguda görülmüştür (%0.07). Diyabet olguların %4.3’ünde risk faktörü olarak karşımıza çıkmıştır. 6 hasta(%0.4) myokard enfarktüsü nedeniyle hastanede kaldığı sürede kaybedilmiştir. Sonuç: Bizim bulgularımıza gore güneydoğu İranda hastanede yatan yaşlı hastalarda TB ve bronkopulmoner infeksiyonlar en sık görülen inkesiyonlardır. Inşuenza ve pnömokok aşıları bu grupta infeksiyon sıklığını azaltabilir..

Güney doğu Iran’da hastanede yatan yaşlı hastalarda infeksiyöz hastalık spektrumu

Aim: The elderly have defective host defenses that compromise their ability to ward off infectious agents; factors influencing immunocompetence include impaired host defenses such as diminished cell-mediated immunity, changes in chronic diseases, medications, malnutrition and functional impairments. This study was conducted in order to determine the pattern of clinical infectious diseases in a series of hospitalized elderly patients. Materials and Methods: In this cross-sectional study, all elderly patients who were admitted to our hospital in Zahedan (Southeast Iran) between 2001 and 2006 were evaluated. We retrospectively reviewed the 1278 patients for diagnostic studies, risk factors, treatment options and morbidity and mortality rate. Results: Tuberculosis (TB) was the commonest infection (46%), followed by pneumonia (14.9%), bronchitis (13%), gastroenteritis (6.5%) and sepsis (3.9%). Most of the cases of TB were pulmonary (98.2%). Pulmonary aspergillosis was seen in only one case and was the least common infection in our patients (0.07%). Diabetes was seen as a risk factor in 4.3% of our patients. Six patients (0.4%) died during hospital stay due to myocardial infarction. Conclusions: Based on the results from this study, TB and bronchopulmonary infections are the most common infections in hospitalized elderly patients in the Southeast of Iran. Influenza and pneumococcal vaccines can limit the bronchopulmonary infections in this group.

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