Osman CELBİŞ, Mehmet Tahir GÖKDEMİR, Özgür SÖĞÜT, Halil KAYA, Bora ÖZDEMİR, Atılhan KAYA

Oxidative stress status of individuals involved in traffic accidents

Amaç: Bu çalışmanın amacı trafik kazasına karışmış sürücülerde oksidatif stress durumunun risk faktörü olarak rolünü araştırmaktır. Yöntem ve gereç: Trafik kazalarına karışmış 26 sürücü ve 28 yolcu ile 31 sağlıklı kontrol sürücü ve 30 sağlıklı kontrol yaya çalışmaya dahil edildi. Kan örneklerinde toplam antioksidan kapasite (TAK) ve toplam oksidan seviye (TOS) çalışıldı. Bulgular: Kazaya karışan sürücülerin ortalama TOS değeri kontrol yayaların ortalama TOS değerinden anlamlı olarak yüksek bulundu (P ≤ 0,05). Kazaya karışan yolcuların ortalama TAK değeri ise kontrol sürücülerin ve kontrol yayaların ortalama TAK değerlerinden anlamlı olarak düşüktü (sırasıyla, P ≤ 0,001 ve P ≤ 0,01). Sonuç: Çalışmamız kazaya karışan sürücü ve yolcularda oksidatif ve antioksidatif durumu değerlendiren ve kontrol grupları ile kıyaslama yapan ilk çalışmadır. Sonuçlarımız kazaya karışma durumunun oksidatif stres belirteçleri üzerine etkisi olduğunu göstermektedir. Ancak trafik kazasına karışmış sürücülerde oksidatif stres durumunun kaza yapma riskini tahmin etmede bir belirteç olarak kullanılabilmesi için daha fazla sayıda çalışmalar gerekmektedir.

Trafik kazalarına karışmış kişilerde oksidatif stres durumu

Aim: To investigate the role of the oxidative stress status of drivers involved in traffic accidents as a risk factor. Materials and methods: Twenty-six drivers and 28 passengers involved in traffic accidents and 31 healthy control drivers and 30 healthy control pedestrians were enrolled in the present study. The total antioxidant status (TAS) and total oxidant status (TOS) were measured in blood samples. Results: The mean value of the TOS level in drivers involved in traffic accidents was significantly higher than that of the control pedestrians (P ≤ 0.05). The mean value of the TAS level in passengers involved in traffic accidents was significantly lower than that of the control drivers and pedestrians (P ≤ 0.001 and P ≤ 0.01, respectively). Conclusion: This is the first study assessing the oxidative markers of individuals involved in a traffic accident compared with a control group. The results reveal that involvement in a traffic accident has an effect on oxidative markers. However, further studies are required in order to use the oxidative stress status of drivers involved in traffic accidents as a marker for estimating the accident risk.

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