Mehmet Sezai TAŞBAKAN, Özen Kaçmaz BAŞOĞLU, İlgin Yildirim ŞİMŞİR, Lütfiye Füsun SAYGILI

Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy

Öz Background/aim: Acromegaly is often associated with obstructive sleep apnea syndrome (OSAS) with a frequency between 40% and 80%. The aim of the present study was to evaluate the clinical and polysomnographic characteristics of acromegaly patients with sleep apnea symptoms and to identify positive airway pressure (PAP) adherence in acromegaly patients with OSAS diagnosis.Materials and methods: Twenty-eight well-controlled acromegaly patients (17 males, mean age 48.7 $\pm$ 10.1 years) with sleep apnea symptoms were included in this prospective study. Demographic data, anthropometric measurements, and medical history were evaluated. Full-night in-laboratory polysomnography was performed.Results: Polysomnography results showed that 25 patients (89.3%) had OSAS with a mean apnea-hypopnea index (AHI) of 37.7 $\pm$ 28.8/h. All 17 male patients were diagnosed with OSAS, whereas 8 female patients (72.7%) had OSAS (P = 0.05). Male patients also had more severe OSAS than females (AHI 48.3 $\pm$ 29.0 vs. 21.3 $\pm$ 20.1 events/h, respectively; P = 0.012). Twenty-two patients out of 28 were considered to be eligible candidates for PAP therapy. The PAP adherence rate was found to be 50% during follow-up. Conclusion: Our results confirm OSAS as a common disorder in acromegaly patients as well as PAP therapy being required for a majority of patients. Therefore, all acromegaly patients should be assessed in terms of OSAS and be followed closely for the evaluation of PAP adherence.

Anahtar Kelimeler:

Acromegaly, sleep apnea, positive airway pressure, adherence

Tam Metin

Kaynak Göster

Bibtex	@ { tbtkmedical576359, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2017}, volume = {47}, pages = {1348 - 1353}, doi = {}, title = {Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy}, key = {cite}, author = {Taşbakan, Mehmet Sezai and Başoğlu, Özen Kaçmaz and Şimşir, İlgin Yildirim and Saygılı, Lütfiye Füsun} }
APA	Taşbakan, M , Başoğlu, Ö , Şimşir, İ , Saygılı, L . (2017). Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy . Turkish Journal of Medical Sciences , 47 (5) , 1348-1353 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576359
MLA	Taşbakan, M , Başoğlu, Ö , Şimşir, İ , Saygılı, L . "Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy" . Turkish Journal of Medical Sciences 47 (2017 ): 1348-1353 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576359>
Chicago	Taşbakan, M , Başoğlu, Ö , Şimşir, İ , Saygılı, L . "Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy". Turkish Journal of Medical Sciences 47 (2017 ): 1348-1353
RIS	TY - JOUR T1 - Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy AU - Mehmet Sezai Taşbakan , Özen Kaçmaz Başoğlu , İlgin Yildirim Şimşir , Lütfiye Füsun Saygılı Y1 - 2017 PY - 2017 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 1348 EP - 1353 VL - 47 IS - 5 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote	%0 Turkish Journal of Medical Sciences Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy %A Mehmet Sezai Taşbakan , Özen Kaçmaz Başoğlu , İlgin Yildirim Şimşir , Lütfiye Füsun Saygılı %T Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy %D 2017 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 47 %N 5 %R %U
ISNAD	Taşbakan, Mehmet Sezai , Başoğlu, Özen Kaçmaz , Şimşir, İlgin Yildirim , Saygılı, Lütfiye Füsun . "Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy". Turkish Journal of Medical Sciences 47 / 5 (Ekim 2017): 1348-1353 .
AMA	Taşbakan M , Başoğlu Ö , Şimşir İ , Saygılı L . Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy. Turkish Journal of Medical Sciences. 2017; 47(5): 1348-1353.
Vancouver	Taşbakan M , Başoğlu Ö , Şimşir İ , Saygılı L . Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy. Turkish Journal of Medical Sciences. 2017; 47(5): 1348-1353.
IEEE	M. Taşbakan , Ö. Başoğlu , İ. Şimşir ve L. Saygılı , "Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy", Turkish Journal of Medical Sciences, c. 47, sayı. 5, ss. 1348-1353, Eki. 2017