Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women

Öz Background/aim: This study aimed to investigate the correlation between the prevalence of problematic pathogens and the clinical status of women with bacterial vaginosis (BV). Materials and methods: Gardnerella vaginalis, Atopobium vaginae, and Mobiluncus spp. were detected using a multiplex PCR assay, and their role in the infection of Bulgarian women with clinically heterogeneous BV was evaluated. Results: The predominant BV-associated pathogen identified was G. vaginalis with an incidence of 98.39%, followed by A. vaginae (68.05%) and Mobiluncus spp. at 17.01%. The coexistence of A. vaginae and G. vaginalis was more common in women with discharge (in 72.04%) and in patients with chronic recurrent BV than among asymptomatic or newly diagnosed BV cases (P < 0.05). Mobiluncus spp. was detected mostly in coinfections, in association with Trichomonas vaginalis. The coinfections were predominantly related to recurrent BV and with complications (P < 0.05). Conclusion: This is the first study about the correlation between problematic pathogens and clinically heterogeneous BV in Bulgarian women. High frequency of infection with key BV-related pathogens was observed in childbearing women. The incidence was shown to often correlate with coexistent T. vaginalis, with severity of infection, and with complicated and recurrent BV after unsuccessful treatments. Screening should be considered in reproductive health programs.

Kaynak Göster

Bibtex @ { tbtkmedical576378, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2017}, volume = {47}, pages = {1492 - 1499}, doi = {}, title = {Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women}, key = {cite}, author = {Tosheva-daskalova, Konstantsa and Strateva, Tanya Vasileva and Mıtov, İvan Gergov and Gergova, Raina Tzvetanova} }
APA Tosheva-daskalova, K , Strateva, T , Mıtov, İ , Gergova, R . (2017). Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women . Turkish Journal of Medical Sciences , 47 (5) , 1492-1499 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576378
MLA Tosheva-daskalova, K , Strateva, T , Mıtov, İ , Gergova, R . "Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women" . Turkish Journal of Medical Sciences 47 (2017 ): 1492-1499 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576378>
Chicago Tosheva-daskalova, K , Strateva, T , Mıtov, İ , Gergova, R . "Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women". Turkish Journal of Medical Sciences 47 (2017 ): 1492-1499
RIS TY - JOUR T1 - Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women AU - Konstantsa Tosheva-daskalova , Tanya Vasileva Strateva , İvan Gergov Mıtov , Raina Tzvetanova Gergova Y1 - 2017 PY - 2017 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 1492 EP - 1499 VL - 47 IS - 5 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women %A Konstantsa Tosheva-daskalova , Tanya Vasileva Strateva , İvan Gergov Mıtov , Raina Tzvetanova Gergova %T Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women %D 2017 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 47 %N 5 %R %U
ISNAD Tosheva-daskalova, Konstantsa , Strateva, Tanya Vasileva , Mıtov, İvan Gergov , Gergova, Raina Tzvetanova . "Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women". Turkish Journal of Medical Sciences 47 / 5 (Ekim 2017): 1492-1499 .
AMA Tosheva-daskalova K , Strateva T , Mıtov İ , Gergova R . Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women. Turkish Journal of Medical Sciences. 2017; 47(5): 1492-1499.
Vancouver Tosheva-daskalova K , Strateva T , Mıtov İ , Gergova R . Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women. Turkish Journal of Medical Sciences. 2017; 47(5): 1492-1499.
IEEE K. Tosheva-daskalova , T. Strateva , İ. Mıtov ve R. Gergova , "Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women", Turkish Journal of Medical Sciences, c. 47, sayı. 5, ss. 1492-1499, Eki. 2017

7682 5640

Arşiv
Sayıdaki Diğer Makaleler

Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery

Mediha TÜRKTAN, Yasemin GÜNEŞ, Hafize YALINIZ, Selçuk MATYAR, Zehra HATİPOĞLU, Ersel GÜLEÇ, Uğur GÖÇEN, Atakan ATALAY

Relationship between kinesiophobia and pain, quality of life, functional status, disease activity, mobility, and depression in patients with ankylosing spondylitis

Deran OSKAY, Zeynep TUNA, İrem DÜZGÜN, Bülent ELBASAN, Yavuz YAKUT, Abdurrahman TUFAN

Unknown vascular compression of the airway in patients with congenitalheart disease and persistent lower respiratory symptoms

Tuğba Şişmanlar EYÜBOĞLU, Ayşe Tana ASLAN, Çiğdem ÖZTUNALI, Fatma Sedef TUNAOĞLU, Ayşe Deniz OĞUZ, Serdar KULA, Betül Emine DERİNKUYU, Öznur Leman BOYUNAGA

The effects of the number of physical therapy sessions on pain, disability,and quality of life in patients with chronic low back pain

Burcu Metin ÖKMEN, Engin KOYUNCU, Bilal UYSAL, Neşe ÖZGİRGİN

Patients' attitudes and knowledge about drug use: a survey in Turkish family healthcare centres and state hospitals

Ahmet AKICI, Salih MOLLAHALİLOĞLU, Başak DÖNERTAŞ, Şenay ÖZGÜLCÜ, Ali ALKAN, Nesrin Filiz BAŞARAN

Eleven patients with primary thyroid lymphoma: a single center experience

Hasan BOSTANCI, Kürşat DİKMEN, Nalan AKYÜREK, Ahmet Çağri BÜYÜKKASAP, Aydin YAVUZ, Mehmet Muhittin YALÇIN, Murat AKIN

Multiplex PCR detection of problematic pathogens of clinically heterogeneous bacterial vaginosis in Bulgarian women

Konstantsa TOSHEVA-DASKALOVA, Tanya Vasileva STRATEVA, İvan Gergov MITOV, Raina Tzvetanova GERGOVA

Mean ADC values discriminate rectal mucinous carcinomafrom rectal nonmucinous adenocarcinoma

Hale Çolakoğlu ER, Gül Ayşe ERDEN

Role of baseline adenoma characteristics for adenoma recurrencein patients with high-risk adenoma

Tevfik SOLAKOĞLU, Hüseyin KÖSEOĞLU, Sevil Özer SARI, Fatma Ebru AKIN, Aylin Demirezer BOLAT, Öykü Tayfur YÜREKLİ, Naciye Şemnur BÜYÜKAŞIK, Osman ERSOY

Investigation of human leukocyte antigen in osteoarticular brucellosis

Sevim GÖNEN, Murat DİZBAY, Hüsnü Oğuz SÖYLEMEZOĞLU