Identification of Fibronectin Adhesins on Candida albicans

The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.

Identification of Fibronectin Adhesins on Candida albicans

The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.