Epidemiology of uveitis in a referral hospital in Turkey

To investigate the causes and clinical characteristics of uveitis in patients presenting to a specialized eye hospital in Turkey. Materials and methods: The clinical records of 1028 uveitis patients admitted between 1990 and 2010 were retrospectively reviewed. Age at first presentation, sex, laterality, etiology, associated systemic disease, clinical presentation, and course of the disease were noted. Results: The mean age at presentation was 36.23 ± 14.9 years. Males constituted 58.2% of patients. Anatomically, anterior uveitis (42%) was most common, followed by posterior uveitis (24.9%), panuveitis (24.7%), and intermediate uveitis (8.4%). The course of the disease was mostly chronic (65.7%). The cases were idiopathic at 25.7% and Behçet's disease (BD) was the most common cause of uveitis (32.2%), followed by ocular toxoplasmosis (7.2%) and herpetic uveitis (6.8%). Conclusion: Uveitis tends to affect patients between 20 and 40 years old. BD is the most common cause, leading to male predominance and a higher frequency of a chronic course.

Epidemiology of uveitis in a referral hospital in Turkey

To investigate the causes and clinical characteristics of uveitis in patients presenting to a specialized eye hospital in Turkey. Materials and methods: The clinical records of 1028 uveitis patients admitted between 1990 and 2010 were retrospectively reviewed. Age at first presentation, sex, laterality, etiology, associated systemic disease, clinical presentation, and course of the disease were noted. Results: The mean age at presentation was 36.23 ± 14.9 years. Males constituted 58.2% of patients. Anatomically, anterior uveitis (42%) was most common, followed by posterior uveitis (24.9%), panuveitis (24.7%), and intermediate uveitis (8.4%). The course of the disease was mostly chronic (65.7%). The cases were idiopathic at 25.7% and Behçet's disease (BD) was the most common cause of uveitis (32.2%), followed by ocular toxoplasmosis (7.2%) and herpetic uveitis (6.8%). Conclusion: Uveitis tends to affect patients between 20 and 40 years old. BD is the most common cause, leading to male predominance and a higher frequency of a chronic course.

___

  • Durrani OM, Tehrani NN, Marr JE, Moradi P, Stavrou P, Murray PI. Degree, duration, and causes of visual loss in uveitis. Br J Ophthalmol 2004; 88: 1159–1162. 2. Nussenblatt RB The natural history of uveitis. Int Ophthalmol 1990; 14: 303–308.
  • Wakefield D, Chang JH. Epidemiology of uveitis. Int Ophthalmol Clin 2005; 45: 1–13.
  • Weiner A, BenEzra D. Clinical patterns and associated conditions in chronic uveitis. Am J Ophthalmol 1991; 112: 151–158. 5. Singh R, Gupta V, Gupta A. Pattern of uveitis in a referral eye clinic in north India. Indian J Ophthalmol 2004; 52: 121–125.
  • Gritz DC, Wong IG. Incidence and prevalence of uveitis in Northern California; the Northern California Epidemiology of Uveitis Study. Ophthalmology 2004; 111: 491–500.
  • Yang P, Zhang Z, Zhou H, Li B, Huang X, Gao Y, Zhu L, Ren Y, Klooster J, Kijlstra A. Clinical patterns and characteristics of uveitis in a tertiary center for uveitis in China. Curr Eye Res 2005; 30: 943–948.
  • Khairallah M, Yahia SB, Ladjimi A, Messaoud R, Zaouali S, Attia S, Jenzeri S, Jelliti B. Pattern of uveitis in a referral centre in Tunisia, North Africa. Eye (Lond) 2007; 21: 33–39.
  • Şengün A, Karadağ R, Karakurt A, Sarıcaoğlu MS, Abdik O, Hasıripi H. Causes of uveitis in a referral hospital in Ankara, Turkey. Ocul Immunol Inflam 2005; 13: 45–50.
  • Kazokoglu H, Onal S, Tugal-Tutkun I, Mirza E, Akova Y, Ozyazgan Y, Soylu M, Batıoglu F, Apaydin C. Demographic and clinical features of uveitis in tertiary centers in Turkey. Ophthalmic Epidemiol 2008; 15: 285–293.
  • Goto H, Mochizuki M, Yamaki K, Kotake S, Usui M, Ohno S. Epidemiological survey of intraocular inflammation in Japan. Jpn J Ophthalmol 2007; 51: 41–44.
  • Rathinam SR, Namperumalsamy P. Global variation and pattern changes in epidemiology of uveitis. Indian J Ophthalmol 2007; 55: 173–183.
  • Wakabayashi T, Morimura Y, Miyamoto Y, Okada AA. Changing patterns of intraocular inflammatory disease in Japan. Ocul Immunol Inflam 2003; 11: 277–286.
  • Suzuki J, Oh IK, Kezuka T, Sakai J, Goto H. Comparison of patients with ocular tuberculosis in the 1990s and the 2000s. Jpn J Ophthalmol 2010; 54: 19–23.
  • Yoshida A, Kawashima H, Motoyama Y, Goto H. Comparison of patients with Behcet’s disease in the 1980s and 1990s. Ophthalmology 2004; 111: 810–815.
  • Henderly DE, Genstler AJ, Smith RE, Rao NA. Changing patterns of uveitis. Am J Ophthalmol 1987; 103: 131–136.
  • Jabs DA, Nussenblatt RB, Rosenbaum JT. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 2005; 140: 509–516.
  • [No authors listed.] Criteria for diagnosis of Behcet’s disease. International Study Group for Behcet’s Disease. Lancet 1990; 335: 1078–1080.
  • Chams HRM, Mohammadi SF, Ohno S. Epidemiology and prevalence of uveitis: review of literature. Iranian J Ophthalmol 2009; 21: 4–16.
  • Rothova A, Buitenhuis HJ, Meenken C, Brinkman CJ, Linssen A, Alberts C, Luyendijk L, Kijlstra A. Uveitis and systemic disease. Br J Ophthalmol 1992; 76: 137–141.
  • Smit RL, Baarsma GS, de Vries J. Classification of 750 consecutive uveitis patients in the Rotterdam Eye Hospital. Int Ophthalmol 1993; 17: 71–76.
  • Rodriguez A, Calonge M, Pedroza-Seres M, Akova YA, Messmer EM, D’Amico DJ, Foster CS. Referral patterns of uveitis in a tertiary eye care center. Arch Ophthalmol 1996; 114: 593–599.
  • McCannel CA, Holland GN, Helm CJ, Cornell PJ, Winston JV, Rimmer TG . Causes of uveitis in the general practice of ophthalmology UCLA Community-Based Uveitis Study Group. Am J Ophthalmol 1996; 121: 35–46.
  • Ayanru JO. The problem of uveitis in Bendel State of Nigeria: experience in Benin City. Br J Ophthalmol 1977; 61: 655–659.
  • Ronday MJ, Stilma JS, Barbe RF, McElroy WJ, Luyendijk L, Kolk AH, Bakker M, Kijlstra A, Rothova A. Aetiology of uveitis in Sierra Leone, West Africa. Br J Ophthalmol 1996; 80: 956–961.
  • Consul BN, Sharma DP, Chhabra HN, Sahai R. Uveitis: etiological pattern in India. Eye, Ear, Nose & Throat Monthly 1972; 51: 122–127.
  • Islam SM, Tabbara KF. Causes of uveitis at The Eye Center in Saudi Arabia: a retrospective review. Ophthalmic Epidemiol 2002; 9: 239–249.
  • Chung YM, Yeh TS, Liu JH. Endogenous uveitis in Chinese- -an analysis of 240 cases in a uveitis clinic. Jpn J Ophthalmol 1988; 32: 64–69.
  • Soheilian M, Heidari K, Yazdani S, Shahsavari M, Ahadieh H, Dehghan M. Patterns of uveitis in a tertiary eye care center in Iran. Ocul Immunol Inflam 2004; 12: 297–310.
  • Nussenblatt RB. (2002). Uveitis: Fundamentals and Clinical Practice. 3rd ed. Philadelphia, PA, USA: Mosby; 2002.
  • Chang JH, Wakefield D. Uveitis: a global perspective. Ocul Immunol Inflam 2002; 10: 263–279.
  • Ozdal PC, Ortac S, Taskintuna I, Firat E. Posterior segment involvement in ocular Behcet’s disease. Eur J Ophthalmol 2002; 12: 424–431.
  • Glasner PD, Silveira C, Kruszon-Moran D, Martins MC, Burnier Jşnior M, Silveira S, Camargo ME, Nussenblatt RB, Kaslow RA, Belfort Jşnior R. An unusually high prevalence of ocular toxoplasmosis in southern Brazil. Am J Ophthalmol 1992; 114: 136–144.
  • Merrill PT, Kim J, Cox TA, Betor CC, McCallum RM, Jaffe GJ. Uveitis in the southeastern United States. Curr Eye Res 1997; 16: 865–874.
  • [No authors listed.] A controlled trial of oral acyclovir for iridocyclitis caused by herpes simplex virus. The Herpetic Eye Disease Study Group. Arch Ophthalmol 1996; 114: 1065–1072.
  • Chan SM, Hudson M, Weis E. Anterior and intermediate uveitis cases referred to a tertiary centre in Alberta. Can J Ophthalmol 2007; 42: 860–864.
  • Tugal-Tutkun I, Guney-Tefekli E, Kamaci-Duman F, Corum I. A cross-sectional and longitudinal study of Fuchs uveitis syndrome in Turkish patients. Am J Ophthalmol 2009; 148: 510–515.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Pediatric reference intervals for plasma and urine essential amino acids in a Turkish population

Enis MACİT, Murat KIZILGÜN, Erdinç ÇAKIR, Abdulbaki KARAOĞLU, Emin Özgür AKGÜL, Muzaffer ÖZTOSUN, İbrahim AYDIN, Fevzi Nuri AYDIN, Mehmet AĞILLI, Türker TÜRKER, Recai OĞUR, Yasemin GÜLCAN KURT, Hüsamettin GÜL, Tuncer ÇAYCI, Esin ÖZKAN

Comparison of disc and body volumes in degenerated and nondegenerated lumbar discs: a stereological study

Tuncay KANER, Ahmet SONGUR, Muhsin TOKTAŞ, Ozan Alper ALKOÇ, Olcay ESER, Mustafa EFENDİOĞLU

Prevalence study of genital tract infections in pregnant women referred to health centers in Iran

Mahmoud MOBASHERI, Narges Saeedi VARNAMKHAST, Ali KARIMI, Shayesteh BANAEIYAN

Hemodynamic effects of chest-knee position: comparison of perioperative propofol and sevoflurane anesthesia

Yusuf ÜNAL, Hatice Zerrin ÖZKÖSE, Recep Şahin YARDIM, Berrin IŞIK, Hasan Kutluk PAMPAL

Intrathoracic Castleman disease

Pınar BIÇAKÇIOĞLU, Selim Şakir Erkmen GÜLHAN, Leyla Nesrin ACAR, Yetkin AĞAÇKIRAN, Şeref ÖZKARA, Sadi KAYA, Nurettin KARAOĞLANOĞLU

Assessment of left ventricular function by strain strain rate echocardiography in patients with celiac disease

Osman ERSOY, Hüseyin AYHAN, Cenk SARI, Serdal BAŞTUĞ, Fatma Ebru AKIN, Nihal BAYRAM AKAR, Aylin BOLAT DEMİREZER, Sevil SARI ÖZER, Emine BİLEN, Telat KELEŞ, Tahir DURMAZ, Engin BOZKURT

Anti TNF-α therapy might be responsible for an increased incidence of varicocele in patients with ankylosing spondylitis

Mahmut YENER, Mehmet UMUL, Elif Nisa ÜNLÜ, Yunus UGAN, Meltem ÇETİN, Bumin DEĞİRMENCİ, Bünyamin KISACIK, Mustafa KAYAN, Aykut Recep AKTAŞ, Ömer YILMAZ

MEFV mutation frequency and effect on disease severity in ankylosing spondylitis

Yüksel MARAŞ, Ali AKDOĞAN, Bünyamin KISACIK, Levent KILIÇ, Engin YILMAZ, Abdurrahman TUFAN, Umut KALYONCU, Şaziye Şule APRAŞ BİLGEN, Sedat KİRAZ, Ali İhsan ERTENLİ, Meral ÇALGÜNERİ

The place of androgen receptor gene mutation analysis in the molecular diagnosis of prostate cancer and genotype–phenotype relationship

Fuat KIZILAY, Mustafa Serdar KALEMCİ, Adnan ŞİMŞİR, Burak TURNA, Oktay NAZLI, Afig BERDELİ

Assessment of left ventricular function by strain–strain rate echocardiography in patients with celiac disease

Cenk SARI, Aylin DEMİREZER BOLAT, Fatma Ebru AKIN, Nihal AKAR BAYRAM, Sevil ÖZER SARI, Serdal BAŞTUĞ, Emine BİLEN, Hüseyin AYHAN, Telat KELEŞ, Tahir DURMAZ, Osman ERSOY, Engin BOZKURT