Developing the Nausea and Vomiting Thermometer Scale in children with cancer

Background/aim: This study aimed to develop the Nausea and Vomiting Thermometer Scale (NVTS) in children with cancer. Materials and methods: This methodological study was conducted on 250 children with cancer at the research and training university hospital in Turkey between September 2019 and January 2020. The t-test, the ROC analysis, the Diagnostic index, and the Youden index were used for determining the scale of the cutting point. The regression analysis, the intra-class correlation coefficient, and the Bland– Altman analysis were used for the data analysis. Results: The scale-level content validity index was .94, which was coherent. As a result of the ROC analysis, the cut-off point was determined as three points. The NVTS showed good reliability, with an intra-class correlation coefficient of .99. In the linear regression analysis, a model was created for chemotherapy drugs, nausea and vomiting type, vomiting status, and the number of children with cancer who vomited explained 44.9% of their nausea and vomiting status. The results of the Bland–Altman analysis showed that the correlation coefficient between the differences and the means was insignificant. Conclusion: The NVTS was found to be a valid and reliable measurement tool for children with cancer in the Turkish sample.

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1. Miller E, Jacob E, Hockenberry MJ. Nausea, pain, fatigue, and multiple symptoms in hospitalized children with cancer. Oncology Nursing Forum 2011; 38: 382–393. doi: 10.1188/11. ONF.E382-E393
2. Rodgers C, Hooke MC, Ward J, Linder LA. Symptom clusters in children and adolescents with cancer. Seminars in Oncology Nursing 2016; 32: 394-404. doi: 10.1016/j.soncn.2016.08.005
3. Esenay FI, Sezer TA, Turan SA. Causal perceptions in Turkish parents of children with cancer (article in Turkish with an abstract in English). Turkish Journal of Oncology 2018; 33: 94- 101. doi: https://doi.org/10.5505/tjo.2018.1788
4. Jordan K, Roila F, Molassiotis A, Maranzano E, Clark-Snow RA et al. Antiemetics in children receiving chemotherapy. MASCC/ESMO guideline update 2009. Supportive Care in Cancer 2011; 19: 37-42. doi: https://doi.org/10.1007/s00520- 010-0994-7
5. Rodgers C, Kollar D, Taylor O, Bryant R, Crockett K et al. Nausea and vomiting perspectives among children receiving moderate to highly emetogenic chemotherapy treatment. Cancer Nursing 2012; 35: 203-210. doi: https://doi.org/10.1097/ NCC.0b013e3182281493
6. Flank J, Robinson PD, Holdsworth M, Phillips R, Portwine C et al. Guideline for the treatment of breakthrough and the prevention of refractory chemotherapy-induced nausea and vomiting in children with cancer. Pediatric Blood & Cancer 2016; 63: 1144-1151. doi.https://doi.org/10.1002/pbc.25955
7. Roila F, Molassiotis A, Herrstedt J, Aapro M, Gralla RJ et al. 2016 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting and of nausea and vomiting in advanced cancer patients. Annals of Oncology 2016; 27: v119-133. doi: https:// doi.org/10.1093/annonc/mdw270
8. Dupuis LL, Taddio A, Kerr EN, Kelly A, MacKeigan L. Development and validation of the pediatric nausea assessment tool for use in children receiving antineoplastic agents. Pharmacotherapy 2006; 26: 1221-1231. doi: https://doi. org/10.1592/phco.26.9.1221
9. Patel GS, Jain K, Kumar R, Strickland AH, Pellegrini L et al. Comparison of peripherally inserted central venous catheters (PICC) versus subcutaneously implanted portchamber catheters by complication and cost for patients receiving chemotherapy for non-haematological malignancies. Supportive Care in Cancer 2014; 22: 121-128. doi: https://doi. org/10.1007/s00520-013-1941-1
10. Velez-Florez G, Velez-Florez MC, Mantilla-Rivas JO, Patarroyo-Rodríguez L, Borrero-León R et al. Mind-body therapies in childhood cancer. Current Psychiatry Reports 2018; 20: 1-12. doi: https://doi.org/10.1007/s11920-018-0927-6
11. Kristjánsdóttir Ó, Unruh AM, McAlpine L, McGrath PJ. A systematic review of cross-cultural comparison studies of child, parent, and health professional outcomes associated with pediatric medical procedures. The Journal of Pain 2012; 13 :207-219. doi: https://doi.org/10.1016/j.jpain.2011.12.008
12. Riley AW. Evidence that school-age children can self-report on their health. Ambulatory Pediatrics 2004; 4: 371-376. doi: https://doi.org/10.1367/A03-178R.1
13. Glasgow RE, Estabrooks PE. Pragmatic applications of REAIM for health care initiatives in community and clinical settings. Preventing Chronic Disease 2018; 15: 170271. doi: https://doi.org/10.5888/pcd15.170271
14. Şişman H, Eti Aslan F, Özgen R, Alptekin D, Akil Y. Validity and reliability study of the Baxter Animated Retching Faces Nausea Scale. Journal of Pediatric Surgical Nursing 2016; 5: 98- 106. https://doi.org/10.1097/jps.0000000000000114
15. Akçay Didişen N, Yavuz B, Yardimci F, Basbakkal DZ. Validity and reliability of the Turkish version of the Adapted Rhodes Index of Nausea and Vomiting for Pediatrics by child (ARINVc) and by parent (ARINVp). Journal of Pediatric Oncology Nursing 2018; 35: 353-360. https://doi. org/10.1177/1043454218765173
16. Tyc VL, Mulhern RK, Jayawardene D, Fairclough D. Chemotherapy-induced nausea and emesis in pediatric cancer patients: An analysis of coping strategies. Journal of Pain and Symptom Management 1995; 10: 338-347. https://doi. org/10.1016/0885-3924(95)00019-u
17. Baxter AL, Watcha MF, Baxter WV, Leong T, Wyatt MM. Development and validation of a Pictorial Nausea Rating Scale for children. Pediatrics 2011; 127: e1542-1549. https://doi. org/10.1542/peds.2010-1410
18. Şimşek ÖF. Yapısal Eşitlik Modellemesine Giriş - Temel İlkeler ve LISREL Uygulamaları. 1th ed. İstanbul: Ekinoks; 2007.
19. Davis LL. Instrument review: Getting the most from a panel of experts. Applied Nursing Research 1992; 5: 194-197. https:// doi.org/10.1016/S0897-1897(05)80008-4
20. Çapık C, Gözüm S, Aksayan S. Intercultural Scale Adaptation Stages, Language and Culture Adaptation: Updated Guideline (article in Turkish with an abstract in English). Florence Nightingale Journal of Nursing 2018; 26: 199-210. https://doi. org/10.26650/FNJN397481
21. Şencan H. Sosyal ve Davranışsal Ölçümlerde Güvenilirlik ve Geçerlilik. 1th ed. Ankara: Seçkin Yayıncılık; 2005.
22. Polit DF, Beck CT, Owen S V. Focus on research methods: Is the CVI an acceptable indicator of content validity? Appraisal and recommendations. Research in Nursing & Health 2007; 30: 459-467. https://doi.org/10.1002/nur.20199
23. Terwee CB, Bot SDM, de Boer MR, van der Windt DAWM, Knol DL et al. Quality criteria were proposed for measurement properties of health status questionnaires. Journal of Clinical Epidemiology 2007; 60: 34-42. https://doi.org/10.1016/j. jclinepi.2006.03.012
24. Dirican A. Evaluation of the diagnostic testís performance and their comparisons (article in Turkish with an abstract in English). Cerrahpaşa Tıp Dergisi 2001; 32: 25-30.
25. Florkowski CM. Sensitivity, specificity, receiver-operating characteristic (ROC) curves and likelihood ratios: Communicating the performance of diagnostic tests. Clinical Biochemist Reviews 2008; 29 (Suppl 1): S83-87.
26. Lalkhen AG, McCluskey A. Clinical tests: Sensitivity and specificity. Continuing Education in Anaesthesia, Critical Care & Pain 2008; 8: 221-223. https://doi.org/10.1093/BJACEACCP/ MKN041
27. Dewan P, Singhal S, Harit D. Management of chemotherapyinduced nausea and vomiting. Indian Pediatrics 2010; 47: 149- 155. https://doi.org/10.1007/s13312-010-0023-4
28. Hooke MC, Linder LA. Symptoms in children receiving treatment for cancer—Part I: Fatigue, sleep disturbance, and nausea/vomiting. Journal of Pediatric Oncology Nursing 2019; 36: 244-261. https://doi.org/10.1177/1043454219849576
29. Roscoe JA, Morrow GR, Aapro MS, Molassiotis A, Olver I. Anticipatory nausea and vomiting. Supportive Care in Cancer 2011; 19: 1533-1538. https://doi.org/10.1007/s00520-010- 0980-0
30. Özdamar K. Paket programlar ile istatiksel veri analizi : SPSSMINITAB. 1th ed. Eskişehir: Kaan Kitabevi; 2004.
31. Perkins NJ, Schisterman EF. The Youden index and the optimal cut-point corrected for measurement error. Biometrical Journal 2005; 47: 428-441. https://doi.org/10.1002/bimj.200410133
32. Norman GJ, Adams MA, Calfas KJ, Covin J, Sallis JF et al. A randomized trial of a multicomponent intervention for adolescent sun protection behaviors. Archives of Pediatrics and Adolescent Medicine 2007; 161: 146-152. https://doi. org/10.1001/archpedi.161.2.146
33. Bland JM, Altman DG. Measuring agreement in method comparison studies. Statistical Methods in Medical Research 1999; 8: 135-160. https://doi.org/10.1177/096228029900800204
34. Giavarina D. Understanding Bland Altman analysis. Biochemia Medica 2015; 25: 141-151. https://doi.org/10.11613/ BM.2015.015