Tang WEN-HAO,
Zhuang XIN-JIE,
Ma LU-LIN,
QIAO JIE,
Hong KAI,
Zhao LIAN-MING,
Liu DE-FENG,
Mao JIA-MING,
Zhang HONG-LIANG,
Zhou SHAN-JIE,
Jiang HUI
6540
Correlation between body mass index and semen quality in male infertility patients
Background/aim: The question of whether body mass index (BMI) affects semen quality and male fertility is controversial. The purpose of this research was to determine whether there is a correlation between BMI and semen analysis parameters. Materials and methods: A total of 617 male infertility patients were recruited and separated into 3 groups according to BMI values as follows: normal weight group (n = 334), overweight group (n = 220), and obese group (n = 63). Height and weight were measured and a routine semen analysis was performed for all patients. Results: Significant differences existed in BMI, age, and sperm motility (progressive motility) among the 3 groups. BMI and abstinence period were negatively correlated with sperm motility (P < 0.05 and P < 0.01), although they did not correlate with semen volume, total sperm number, concentration, and rate of sperm with normal morphology (P > 0.05). Abstinence, BMI, and age had a linear correlation with sperm motility (P < 0.01) in that order of influence. Conclusion: Sperm motility, an important semen parameter with respect to male fertility, is reduced in men with increased BMI, and BMI is one of the risk factors that influence semen quality.
Correlation between body mass index and semen quality in male infertility patients
Background/aim: The question of whether body mass index (BMI) affects semen quality and male fertility is controversial. The purpose of this research was to determine whether there is a correlation between BMI and semen analysis parameters. Materials and methods: A total of 617 male infertility patients were recruited and separated into 3 groups according to BMI values as follows: normal weight group (n = 334), overweight group (n = 220), and obese group (n = 63). Height and weight were measured and a routine semen analysis was performed for all patients. Results: Significant differences existed in BMI, age, and sperm motility (progressive motility) among the 3 groups. BMI and abstinence period were negatively correlated with sperm motility (P < 0.05 and P < 0.01), although they did not correlate with semen volume, total sperm number, concentration, and rate of sperm with normal morphology (P > 0.05). Abstinence, BMI, and age had a linear correlation with sperm motility (P < 0.01) in that order of influence. Conclusion: Sperm motility, an important semen parameter with respect to male fertility, is reduced in men with increased BMI, and BMI is one of the risk factors that influence semen quality.
___
- Chu KF, Rotker K, Ellsworth P. The impact of obesity on benign
- and malignant urologic conditions. Postgrad Med 2013; 125: 53–69.
- Wang Y, He L, Zhou Z, Jin L, Meng J, Sun G, Na Y. The association between metabolic syndrome and the National Institutes of Health Chronic Prostatitis Symptom Index: results from 1673 men in China. Urology 2013; 82: 1103–1107.
- Duits FH, van Wely M, van der Veen F, Gianotten J. Healthy overweight male partners of subfertile couples should not worry about their semen quality. Fertil Steril 2010; 94: 1356– 1359.
- MacDonald AA, Herbison GP, Showell M, Farquhar CM. The impact of body mass index on semen parameters and reproductive hormones in human males: a systematic review with meta-analysis. Hum Reprod Update 2010; 16: 293–311.
- Håkonsen LB, Thulstrup AM, Aggerholm AS, Olsen J, Bonde JP, Andersen CY, Bungum M, Ernst EH, Hansen ML, Ernst EH et al. Does weight loss improve semen quality and reproductive hormones? Results from a cohort of severely obese men. Reprod Health 2011; 8: 24.
- Sekhavat L, Moein MR. The effect of male body mass index on sperm parameters. Aging Male 2010; 13: 155–158.
- Rybar R, Kopecka V, Prinosilova P, Markova P, Rubes J. Male obesity and age in relationship to semen parameters and sperm chromatin integrity. Andrologia 2011; 43: 286–291.
- Kort HI, Massey JB, Elsner CW, Mitchell-Leef D, Shapiro DB, Witt MA, Roudebush WE. Impact of body mass index values on sperm quantity and quality. J Androl 2006; 27: 450–452.
- Sermondade N, Faure C, Fezeu L, Shayeb AG, Bonde JP, Jensen TK, Van Wely M, Cao J, Martini AC, Eskandar M et al. BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis. Hum Reprod Update 2013; 19: 221–231.
- Paasch U, Grunewald S, Kratzsch J, Glander HJ. Obesity and age affect male fertility potential. Fertil Steril 2010; 94: 2898– 2901.
- Wogatzky J, Wirleitner B, Stecher A, Vanderzwalmen P, Neyer A, Spitzer D, Schuff M, Schechinger B, Zech NH. The combination matters—distinct impact of lifestyle factors on sperm quality: a study on semen analysis of 1683 patients according to MSOME criteria. Reprod Biol Endocrin 2012; 10: 115.
- Macdonald AA, Stewart AW, Farquhar CM. Body mass index in relation to semen quality and reproductive hormones in New Zealand men: a cross-sectional study in fertility clinics. Hum Reprod 2013; 28: 3178–3187.
- Hajshafiha M, Ghareaghaji R, Salemi S, Sadegh-Asadi N, Sadeghi-Bazargani H. Association of body mass index with some fertility markers among male partners of infertile couples. Int J Gen Med 2013; 6: 447–451.
- Pauli EM, Legro RS, Demers LM, Kunselman AR, Dodson WC, Lee PA. Diminished paternity and gonadal function with increasing obesity in men. Fertil Steril 2008; 90: 346–351.
- Relwani R, Berger D, Santoro N, Hickmon C, Nihsen M, Zapantis A, Werner M, Polotsky AJ, Jindal S. Semen parameters are unrelated to BMI but vary with SSRI use and prior urological surgery. Reprod Sci 2011; 18: 391–397.
- Mormandi EA, Otero P, Bertone AL, Calvo M, Astarita G, Kogovsek N, Levalle O. Body weight increase and quality of semen: a controversial association. Endocrinol Nutr 2013; 60: 303–307.
- Eskandar M, Al-Asmari M, Babu Chaduvula S, Al-Shahrani M, Al-Sunaidi M, Almushait M, Donia O, Al-Fifi S. Impact of male obesity on semen quality and serum sex hormones. Adv Urol 2012; 407: 1–4.
- Hofny ER, Ali ME, Abdel-Hafez HZ, Kamal Eel D, Mohamed EE, Abd El-Azeem HG, Mostafa T. Semen parameters and hormonal profile in obese fertile and infertile males. Fertil Steril 2010; 94: 581–584.
- Martini AC, Tissera A, Estofán D, Molina RI, Mangeaud A, de Cuneo MF, Ruiz RD. Overweight and seminal quality: a study of 794 patients. Fertil Steril 2010; 94: 1739–1743.