Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery

Öz Background/aim: Myocardial protection is an important factor of open heart surgery and biological biomarkers (lactate, CKMB, cardiac troponin I, and pyruvate) are used to assess myocardial damage. This study compares the effects of dexmedetomidine and remifentanil on myocardial protection during coronary artery bypass grafting (CABG) surgery. Materials and methods: Patients scheduled for elective CABG surgery (n = 60) were included in this study. Anesthesia induction was introduced with propofol, fentanyl, and vecuronium bromide. Anesthesia was maintained with remifentanil infusion and sevoflurane in the remifentanil group (Group R) and with dexmedetomidine infusion and sevoflurane in the dexmedetomidine group (Group D). Blood samples for biochemical markers were taken from the coronary sinus catheter before cardiopulmonary bypass (T1), 20 min after aortic cross-clamping (T2), 20 min after removal of the aortic cross-clamping (T3), and 10 min after separation from cardiopulmonary bypass (T4).Results: Demographic data were similar between the groups. Lactate level at the T2 period and CKMB levels during the study period were lower in Group D than in Group R. In both groups, all values except pyruvate significantly increased over time. Conclusion: The dexmedetomidine-sevoflurane combination may improve the cardioprotective effect in comparison with remifentanil-sevoflurane in CABG surgery.

Kaynak Göster

Bibtex @ { tbtkmedical576366, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {}, publisher = {TÜBİTAK}, year = {2017}, volume = {47}, pages = {1403 - 1409}, doi = {}, title = {Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery}, key = {cite}, author = {Türktan, Mediha and Güneş, Yasemin and Yalınız, Hafize and Matyar, Selçuk and Hatipoğlu, Zehra and Güleç, Ersel and Göçen, Uğur and Atalay, Atakan} }
APA Türktan, M , Güneş, Y , Yalınız, H , Matyar, S , Hatipoğlu, Z , Güleç, E , Göçen, U , Atalay, A . (2017). Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery . Turkish Journal of Medical Sciences , 47 (5) , 1403-1409 . Retrieved from https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576366
MLA Türktan, M , Güneş, Y , Yalınız, H , Matyar, S , Hatipoğlu, Z , Güleç, E , Göçen, U , Atalay, A . "Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery" . Turkish Journal of Medical Sciences 47 (2017 ): 1403-1409 <https://dergipark.org.tr/tr/pub/tbtkmedical/issue/45689/576366>
Chicago Türktan, M , Güneş, Y , Yalınız, H , Matyar, S , Hatipoğlu, Z , Güleç, E , Göçen, U , Atalay, A . "Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery". Turkish Journal of Medical Sciences 47 (2017 ): 1403-1409
RIS TY - JOUR T1 - Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery AU - Mediha Türktan , Yasemin Güneş , Hafize Yalınız , Selçuk Matyar , Zehra Hatipoğlu , Ersel Güleç , Uğur Göçen , Atakan Atalay Y1 - 2017 PY - 2017 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 1403 EP - 1409 VL - 47 IS - 5 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2021 ER -
EndNote %0 Turkish Journal of Medical Sciences Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery %A Mediha Türktan , Yasemin Güneş , Hafize Yalınız , Selçuk Matyar , Zehra Hatipoğlu , Ersel Güleç , Uğur Göçen , Atakan Atalay %T Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery %D 2017 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 47 %N 5 %R %U
ISNAD Türktan, Mediha , Güneş, Yasemin , Yalınız, Hafize , Matyar, Selçuk , Hatipoğlu, Zehra , Güleç, Ersel , Göçen, Uğur , Atalay, Atakan . "Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery". Turkish Journal of Medical Sciences 47 / 5 (Ekim 2017): 1403-1409 .
AMA Türktan M , Güneş Y , Yalınız H , Matyar S , Hatipoğlu Z , Güleç E , Göçen U , Atalay A . Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery. Turkish Journal of Medical Sciences. 2017; 47(5): 1403-1409.
Vancouver Türktan M , Güneş Y , Yalınız H , Matyar S , Hatipoğlu Z , Güleç E , Göçen U , Atalay A . Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery. Turkish Journal of Medical Sciences. 2017; 47(5): 1403-1409.
IEEE M. Türktan , Y. Güneş , H. Yalınız , S. Matyar , Z. Hatipoğlu , E. Güleç , U. Göçen ve A. Atalay , "Comparison of the cardioprotective effects of dexmedetomidineand remifentanil in cardiac surgery", Turkish Journal of Medical Sciences, c. 47, sayı. 5, ss. 1403-1409, Eki. 2017

9957 8344

Arşiv
Sayıdaki Diğer Makaleler

Impact of body mass index, waist circumference and Pfannenstiel sitetissue thickness, and elastosonography on operative parameters

Serap GÜLTEKİN, İsmail Burak GÜLTEKİN, Zehra Vural YILMAZ, Bilal İÇER, Afra ALKAN, Tuncay KÜÇÜKÖZKAN

Relationship between kinesiophobia and pain, quality of life, functional status, disease activity, mobility, and depression in patients with ankylosing spondylitis

Deran OSKAY, Zeynep TUNA, İrem DÜZGÜN, Bülent ELBASAN, Yavuz YAKUT, Abdurrahman TUFAN

Polymorphisms of cancer-related genes and risk of multipleprimary malignancies involving colorectal cancer

Peiguo CAO, Li YU, Anshan WU, Jingjing LI, Ling LİU, Chunlan LİU, Jianda ZHOU, Ke CAO, Chengxian GUO

DNA methylation of the prestin gene and outer hair cell electromotileresponse of the cochlea in salicylate administration*

Erdoğan BULUT, Metin BUDAK, Levent ÖZTÜRK, Mehmet Turgay TÜRKMEN, Cem UZUN, Tammam SİPAHİ

Exogenous erythropoietin aggravates retinal neovascularizationin a murine model of proliferative retinopathy

Ning YANG, Wenxi ZHANG, Tao HE, Yiqiao XING

Genotype distribution of Mycobacterium tuberculosis in theAegean Region and associated demographic factors

Cengiz ÇAVUŞOĞLU, Fethiye Ferda YILMAZ, İsabel Raika Durusoy ONMUŞ, Tuğba BOZDEMİR, Hüseyin TAŞLI, Mine Hoşgör LİMONCU

Evaluation of risk factors for the recurrence of colorectal polyps and colorectal cancer

Öztürk ATEŞ, Bülent SİVRİ, Saadettin KILIÇKAP

How to manage pseudoangiomatous stromal hyperplasia: our clinical experience

Emine KURT, Sevim TURANLI, Fatma MARKOÇ, Ali Uğur BERBEROĞLU

The clinical features and outcomes of Turkish patients with IgG4-related disease:a single-center experience

Ömer KARADAĞ, Abdulsamet ERDEN, Emine Arzu AYHAN, Ertuğrul Çağri BÖLEK, Umut KALYONCU, Berkan ARMAĞAN, Alper SARI, Levent KILIÇ, Ali AKDOĞAN, Tuncay HAZIROLAN, Bülent AKDOĞAN, Şaziye Şule Apraş BİLGEN, Dilek BAYDAR, Sedat KİRAZ, Ali İhsan ERTENLİ

Investigation of class-d beta-lactamases causing carbapenem resistance in clinical Acinetobacter baumannii isolates

Nurullah ÇAĞIL, Nagihan UĞURLU, Cemil Yunus ŞAHAN, Serhat SEVLİ