Clinical features of infants treated for severe retinopathy of prematurity: 8-yearstudy from a large tertiary neonatal intensive care unit in Turkey

Clinical features of infants treated for severe retinopathy of prematurity: 8-yearstudy from a large tertiary neonatal intensive care unit in Turkey

Background/aim: The aim of this study was to report the gestational age (GA) and birth weight (BW) distribution of premature babies who needed treatment for retinopathy of prematurity (ROP) and to assess the timing of the treatment. Materials and methods: The records of 9008 infants who were screened for ROP were examined and 556 infants who underwent laser therapy for ROP were reviewed. Sex, GA, BW, postnatal age, and postmenstrual (PM) age at the time of laser therapy were recorded. The babies were classified as in-born (Group 1) and out-born infants (Group 2). Results: The mean GA was 27.3 weeks (range: 22 33 weeks) and the mean BW was 991.1 g (range: 520 2160 g). Of the treated infants, 7.0% were born later than 32 weeks and 8.3% were born over 1500 g. The mean postnatal age was 9.48 weeks (range: 5 22 weeks) and the mean PM age was 36.72 weeks (range: 29 48 weeks) at the time of treatment. Mean BWs and GAs were significantly higher and the mean postnatal age at the time of laser therapy was significantly earlier in Group 2. Conclusion: Infants with severe ROP had a wider range of BWs and GAs compared to those from developed countries and earlier treatment was needed for out-born infants.

___

  • 1. Sarikabadayi YU, Aydemir O, Ozen ZT, Aydemir C, Tok L, Oguz SS, Erdeve O, Uraş N, Dilmen U. Screening for retinopathy of prematurity in a large tertiary neonatal intensive care unit in Turkey: frequency and risk factors. Ophthalmic Epidemiol 2011; 18: 269–274.
  • 2. Gilbert C. Retinopathy of prematurity: a global perspective of the epidemics, population of babies at risk and implications for control. Early Hum Dev 2008; 84: 77–82.
  • 3. Gilbert C, Foster A. Childhood blindness in the context of VISION 2020: the right to sight. Bull World Health Organ 2001; 79: 227–232.
  • 4. Erdeve Ö, Atasay B, Arsan S, Batıoğlu F, Atilla H, Türmen T. Restricted universal guidelines for ROP screening: a possible misguidance for middle income countries. Turk J Med Sci 2010; 40: 791–796.
  • 5. Section on Ophthalmology American Academy of Pediatrics; American Academy of Ophthalmology; American Association for Pediatric Ophthalmology and Strabismus. Screening examination of premature infants for retinopathy of prematurity. Pediatrics 2013; 131: 189–195.
  • 6. Fielder AR, Haines L, Scrivener R, Wilkinson AR, Pollock JI; Royal Colleges of Ophthalmologists and Paediatrics and Child Health; the British Association of Perinatal Medicine. Retinopathy of prematurity in the UK II: audit of national guidelines for screening and treatment. Eye 2002; 16: 285–291.
  • 7. Jefferies AL. Retinopathy of prematurity: Recommendations for screening. Paediatr Child Health 2010; 15: 667–670.
  • 8. Early Treatment for Retinopathy of Prematurity Cooperative Group. Results of the early treatment for retinopathy of prematurity randomized trial: revised indications for the treatment of retinopathy of prematurity. Arch Ophthalmol 2003; 121: 1684–1696.
  • 9. Blencowe H, Lawn JE, Vazquez T, Fielders A, Gilbert C. Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010. Pediatr Res 2013; 74: 35–49.
  • 10. Amer M, Jafri WH, Nizami AM, Shomrani AI, Al-Dabaan AA, Rashid K. Retinopathy of prematurity: are we missing any infant with retinopathy of prematurity? Br J Ophthalmol 2012; 96: 1052–1055.
  • 11. Hungi B, Vinekar A, Datti N, Kariyappa P, Braganza S, Chinnaiah S, Donthi K, Shetty B. Retinopathy of prematurity in a rural neonatal intensive care unit in South India—A prospective study. Indian J Pediatr 2012; 79: 911–915.
  • 12. Adio AO, Ugwu RO, Nwokocha CG, Eneh AU. Retinopathy of prematurity in Port Harcourt, Nigeria. ISRN Ophthalmology 2014; 2014: 481527–481533.
  • 13. Akman I, Demirel U, Yenice O, Ilerisoy H, Kazokoğlu H, Ozek E. Screening criteria for retinopathy of prematurity in developing countries. Eur J Ophthalmol 2010; 20: 931–937.
  • 14. Başmak H, Niyaz L, Sahin A, Erol N, Gürsoy HH. Retinopathy of prematurity: screening guidelines need to be reevaluated for developing countries. Eur J Ophthalmol 2010; 20: 752–755.
  • 15. Mutlu FM, Altinsoy HI, Mumcuoglu T, Kerimoglu H, Kiliç S, Kul M, Sarici SU, Alpay F. Screening for retinopathy of prematurity in a tertiary care newborn unit in Turkey: frequency, outcomes, and risk factor analysis. J Pediatr Ophthalmol Strabismus 2008; 45: 291–298.
  • 16. Akcakaya AA, Yaylali SA, Erbil HH, Sadigov F, Aybar A, Aydin N, Akçay G, Acar H, Mesçi C, Yetik H. Screening for retinopathy of prematurity in a tertiary hospital in Istanbul: incidence and risk factors. J Pediatr Ophthalmol Strabismus 2012; 49: 21–25.
  • 17. Araz-Ersan B, Kir N, Akarcay K, Aydinoglu-Candan O, Sahinoglu-Keskek N, Demirel A, Akdogan B, Çoban A. Epidemiological analysis of retinopathy of prematurity in a referral centre in Turkey. Br J Ophthalmol 2013; 97: 15–17.
  • 18. Mutlu FM, Küçükevcilioğlu M, Ceylan OM, Altınsoy Hİ, Sarıcı SÜ. Risk factor analysis for long-term unfavorable ocular outcomes in children treated for retinopathy of prematurity. Turkish J Pediatr 2013; 55: 35–41.
  • 19. Kocabeyoğlu S, Kadayıfcılar S, Eldem B. Retinopathy of prematurity; risk factors, prognosis and treatment. Turkish J Ophthalmol 2011; 41: 128–132.
  • 20. Ugurbas SC, Gulcan H, Canan H, Ankarali H, Torer B, Akova YA. Comparison of UK and US screening criteria for detection of retinopathy of prematurity in a developing nation. AAPOS 2010; 14: 506–510.
  • 21. Alpay A, Uğurbaş SH. Incidence and risk factors for retinopathy of prematurity in the West Black Sea region, Turkey. Turkish J Pediatr 2012; 54: 113–118.
  • 22. Öztürk BT, Kerimoğlu H, Büyükbafl Z, Annagür A, Okka M, Özkağnıcı M. Risk factors, screening and treatment results of retinopathy of premature. Turkish J Ophthalmol 2009; 39: 446–452 (in Turkish with abstract in English).
  • 23. Waal CG, Weisglas-Kuperus N, van Goudoever JB, Walther FJ. Mortality, neonatal morbidity and two year follow-up of extremely preterm infants born in the Netherlands in 2007. PLoS One 2012; 7: e41302.
  • 24. Bayat-Mokhtari M, Pishva N, Attarzadeh A, Hosseini H, Pourarian S. Incidence and risk factors of retinopathy of prematurity among preterm infants in Shiraz/Iran. Iran J Pediatr 2010; 20: 303–307.
  • 25. Kumar P, Sankar MJ, Deorari A, Azad R, Chandra P, Agarwal R, Paul V. Risk factors for severe retinopathy of prematurity in preterm low birth weight neonates. Indian J Pediatr 2011; 78: 812–816.
  • 26. Lai YH, Tseng HI, Yang SN, Hsu HT, Chen HL. Neonatal intensive care unit-specific screening criteria for retinopathy of prematurity. Kaohsiung Journal of Medical Sciences 2012; 28: 601–606.
  • 27. Zin AA, Moreira MEL, Bunce C, Darlow BA, Gilbert CE. Retinopathy of prematurity in 7 neonatal units in Rio de Janeiro: screening criteria and workload implications. Pediatrics 2010; 126: 410–417.
  • 28. Gilbert C, Fielder A, Gordillo L, Quinn G, Semiglia R, Visintin P, Zin A; International NO-ROP Group. Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate, and high levels of development: implications for screening programs. Pediatrics 2005; 115: 518–525.
  • 29. Karkhaneh R, Mousavi SZ, Riazi-Esfahani M, Ebrahimzadeh SA, Roohipoor R, Kadivar M, Ghalichi L, Mohammadi SF, Mansouri MR. Incidence and risk factors of retinopathy of prematurity in a tertiary eye hospital in Tehran. Br J Ophthalmol 2008; 92: 1446–1449.
  • 30. Chen Y, Li XX, Yin H, Gilbert C, Liang JH, Jiang YR, Zhao MW; Beijing ROP Survey Group. Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China. Br J Ophthalmol 2008; 92: 326–330.
  • 31. Yau GS, Lee JW, Tam VT, Liu CC, Chu BC, Yuen CY. Incidence and risk factors for retinopathy of prematurity in extreme low birth weight Chinese infants. Int Ophthalmol 2015; 35: 365– 373.
  • 32. Jalali S, Matalia J, Hussain A, Anand R. Modification of screening criteria for retinopathy of prematurity in India and other middle-income countries. Am J Ophthalmol 2006; 141: 966–968.
  • 33. Aydemir O, Sarikabadayi YU, Aydemir C, Tunay ZO, Tok L, Erdeve O, Oguz SS, Uras N, Dilmen U. Adjusted poor weight gain for birth weight and gestational age as a predictor of severe ROP in VLBW infants. Eye 2011; 25: 725–729.
  • 34. Bozdag S, Oguz SS, Gokmen T, Tunay Z, Tok L, Uras N, Erdeve O, Dilmen U. Serum fructosamine and retinopathy of prematurity. Indian J Pediatr 2011; 78: 1503–1509.
  • 35. Ozdemir O, Tunay ZÖ, Petriçli IS, Acar DE, Acar U, Erol MK. Analysis of the horizontal corneal diameter,  central  corneal  thickness, and axial length in premature infants. Arq Bras Oftalmol 2014; 77: 225–227.
  • 36. Erol MK, Ozdemir MK, Coban DT, Bilgin AB, Dogan B, Sogutlu Sari E, Toslak D. Macular findings obtained by spectral domain optical coherence tomography in retinopathy of prematurity. J Ophthalmol 2014; 2014: 468653.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Intrabone marrow injection enhances placental mesenchymal stem cellmediated support of hematopoiesis in mice

Yan DING, Ya Hong YUAN, Chun Fang ZHOU, Zhi Yong LU, Xiao Li WANG, Dongsheng LI

Simvastatin's effects on survival and outcome in traumatic braininjury patients: a comparative study

Taraneh NAGHIBI, Saideh MAZLOOMZADEH, Faramarz DOBAKHTI, Sara MADANI

Mahmut TOKUR, Mehmet ERGİN, Mehmet OKUMUŞ, Zerrin Defne DÜNDAR

Thi Thuong Lan VO, Bich Thuan TA, Van To TA, Dieu Linh VUONG, Quynh Uyen NGUYEN

Clinical features of infants treated for severe retinopathy of prematurity: 8-yearstudy from a large tertiary neonatal intensive care unit in Turkey

Özdemir ÖZDEMİR, İkbal Seza PETRİÇLİ, Zühal ÖZEN TUNAY, Damla ERGİNTÜRK ACAR, Şerife Suna OĞUZ

Yasemin Bilgin BÜYÜKKARABACAK, Ayşen Taslak ŞENGÜL, Mehmet Gökhan PİRZİRENLİ, Ahmet BAŞOĞLU

The utility of EBUS-TBNA in mediastinal or hilar lymph node evaluation in extrapulmonary malignancy

Serhat EROL, Serir ÖZKAN, Ceyda Mahleç ANAR, Onur Fevzi ERER

Taraneh NAGHIBI, Sara MADANI, Saideh MAZLOOMZADEH, Faramarz DOBAKHTI

An experimental comparative study on classic tube thoracostomy and thoracostomy with a newly designed thorax drainage catheter

Mehmet ERGİN, Mehmet OKUMUŞ, Zerrin Defne DÜNDAR, Mahmut TOKUR

Recurrent dilatation in resistant benign esophageal strictures: timing is significant

Ahmet BAŞOĞLU, Ayşen TASLAK ŞENGÜL, Yasemin BİLGİN BÜYÜKKARABACAK, Mehmet Gökhan PİRZİRENLİ