Evaluation of sarcopenia, sarcopenic obesity, and phase angle in geriatric gastrointestinal cancer patients: before and after chemotherapy

Background/aim: The purpose of this study was to determine sarcopenia, sarcopenic obesity and phase angle (PA) and the influence of chemotherapy (CT) on anthropometric measurements and and the PA in in geriatric patients with gastrointestinal (GI) cancer. Material and methods: The anthropometric measurements, calf circumference (CC), upper midarm circumference (UMAC), and hand grip strength (HGS), have been measured to understand muscle function of 153 patients (mean age of 70.5 ± 5.6 years, 28.8% female, 71.2% male). Sarcopenia and PA measurements have been evaluated by bioelectrical impedance analyses. The same evaluations were checked again after 1 cycle of CT (min: 4, max: 6 weeks). Results: Patient population consisted of colorectal (51,6%), gastric (26.8%), pancreas (11.8%), liver (7.2%), and biliary tract cancer (2%). UMAC (28.5 ± 4.4 before, 28.1 ± 4.9, P = 0.034 after CT), and HGS measurements (27.5 ± 8.6 before, 26.8 ± 8.8 after CT, P = 0.007) have significantly decreased after CT. CC measurement < 31 cm at first visit was seen in 13.1% of patients, but the ratio raised to 20.3% after CT (χ², P = 0.003). Severe sarcopenia was determined in 33% of all patients, and 30.0% of them have been considered as sarcopenic obese. Conclusion: Sarcopenia and sarcopenic obesity were prevalent in this group patients. The CT caused a decrease in muscle functions, UMAC, and CC. Patients should be followed up carefully for sarcopenia, sarcopenic obesity, and nutritional aspect and it would be proper to intervene before sarcopenia has not occurred yet.
Turkish Journal of Medical Sciences-Cover
  • ISSN: 1300-0144
  • Yayın Aralığı: Yılda 6 Sayı
  • Yayıncı: TÜBİTAK
Sayıdaki Diğer Makaleler

Influence of LRP5 (rs556442) polymorphism on insulin resistance in healthy Iranian children and adolescents

Nima MONTAZERI-NAJAFABADY, Rajeeh MOHAMMADIAN AMIRI, Marzieh BAKHSHAYESHKARAM, Mohammad Hossein DABBAGHMANESH, Gholamhossein RANJBAR OMRANI

High neutrophil-to-lymphocyte ratio predicts acute allograft rejection in kidney transplantation: a retrospective study

Ülver DERİCİ, Burak KÖPRÜ, S. Müge DEĞER, Giray ERGİN, Turgay ARINSOY

Sercan ERGÜN, Sezgin GÜNEŞ, Recep BÜYÜKALPELLİ, Oğuz AYDIN

Serhan ÇİMEN, Cemal TAŞDEMİR, Nigar VARDI, Burhan ATEŞ, Seda TAŞDEMİR, Ayla Özaydoğdu ÇİMEN

Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

Mustafa ARICI, Arzu TOPELİ, Tolga YILDIRIM, Abdullah ASLAN, Tural PAŞAYEV, Ömer AKÇAYIR, Sıla ÇETİK, Damla EYÜPOĞLU, Hasan H. YETER

Elevated neutrophil to lymphocyte ratio as an indicator of secondary erythema nodosum, a retrospective observational study

Ayşe ÖKTEM, Başak YALÇIN, Pınar İNCEL UYSAL, Buket ŞAHİN, Yıldız HAYRAN, Nuran ALLI

Antibiotic resistance pattern and spa types of Staphylococcus aureus strains isolated from food business and hospital kitchen employees in Çanakkale, Turkey

Nesrin ÇAKICI, Nükhet Nilüfer DEMİREL ZORBA, Alper AKÇALI

Angel Arturo Lopez GONZALEZ, Felix GRASES, Bartolome MARI, Matias TOMAS-SALVA, Adrian RODRIGUEZ

Is there any difference between endometrial hyperplasia and endometrial carcinoma in terms of expression of TRPM2 and TRPM7 ion channels?

Gökhan ARTAŞ, Şehmus PALA, İlay BURAN, Emre YALÇIN, Ebru ÖNALAN, Remzi ATILGAN, Tuncay KULOĞLU

Efficacy of chemical shift MRI for differentiating diffuse red bone marrow reconversion and hematological malignancies

Burcu AKMAN, Hatice Ayça ATA KORKMAZ, Ahmet SARI