Nalan Metin AKSU, Duygu Yazgan AKSOY, Meltem AKKAŞ, Neşe ÇINAR, Fatma UÇAR, Okan Bülent YILDIZ, Aydan USMAN

Adiponectin levels decrease independently of body mass index and diabetes type after the normalization of hyperglycemia

Background/aim: Acute hyperglycemia is generally a frequently encountered condition in the emergency department ED , because it is seen as a complication of diabetes mellitus DM . In this study, we aimed to detect the change in adiponectin levels during acute hyperglycemic states and after normalization of blood glucose with insulin treatment. Materials and methods: Forty-eight patients over the age of 18 years who were admitted to the ED with acute hyperglycemia were included in the study. Serum samples were taken from patients on admission and 6 h after the normalization of blood glucose with insulin treatment, and adiponectin levels were measured in both samples. Results: There were 21 female and 27 male patients with a median age of 58.7 ± 18 years. All patients' blood glucose levels were normalized with insulin treatment according to international recommendations. Serum adiponectin levels decreased significantly after the normalization of blood glucose in the whole group. Adiponectin levels decreased from 28.9 ± 16.5 to 12.1 ± 10.9 μg/mL P

Keywords:

Hyperglycemia, adiponectin, body mass index,

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