The purpose of the present paper is to establish the rate of convergence for a Lipschitz-type space and obtain the degree of approximation in terms of Lipschitz-type maximal function for the Durrmeyer type modification of Jakimovski-Leviatan operators based on Appell polynomials. We also study the rate of approximation of these operators in a weighted space of polynomial growth and for functions having a derivative of bounded variation.