Çiğdem AYDIN ACAR, Suray PEHLİVANOĞLU, Mehmet KÖK, Gizem YILMAZ

EVALUATION OF SERUM LEVELS OF NETRIN-1 AS A POTENTIAL BIOMARKER FOR EARLY PREDICTION OF PREDIABETES

Objectives: Prediabetes is a candidate status for Type 2 diabetes, typically identified glycemic values range above normal but below diabetes thresholds. Early and accurate diagnosis of this period would be helpful to prevent the diabetes and its consequences. Netrin-1 is a potential metabolic biomarker that has been associated with diabetes. Previous studies are scarce and have yielded contrasting results on serum netrin-1 levels in diabetes. The aim of this study was to investigate the correlation between serum netrin-1 levels and prediabetes. Methods: Sixty nine participants with prediabetes and 35 healthy controls were included in this study. Serum netrin-1 levels were determined using the Enzyme Linked Immunosorbent Assay (ELISA) method. Correlation analysis were done to assess the relationship between serum netrin-1 levels and biochemical parameters. Results: Serum netrin-1 levels were significantly decreased in the prediabetes group compared to the healthy control group (P

Keywords:

Netrin-1, Prediabetes, Biomarker,

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Turkish Journal of Health Science and Life-Cover

ISSN: 2687-2730
Başlangıç: 2018
Yayıncı: Mümin POLAT

Arşiv

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Çiğdem AYDIN ACAR, Suray PEHLİVANOĞLU, Mehmet KÖK, Gizem YILMAZ