Belkıs KOÇTEKİN, Volkan KARAKUŞ, Erdal KURTOĞLU

An investigation of the early and late period effects of the COVID-19 pandemic on blood use and destruction rates: An example of a tertiary hospital, Antalya, Türkiye

Introduction and Objective: The Coronavirus 2019 (COVID-19) pandemic has affected many healthcare services as well as transfusion medicine practices. In this study, it is aimed to examine the early and late effects of the pandemic on the use and destruction rates of blood and blood components. Material and method: This retrospective study was conducted at a tertiary hospital transfusion center. Unit numbers of blood and blood components used and destroyed in 2018-2021 were grouped according to the pre-pandemic period (27 months), early pandemic period (6 months), and late pandemic period (15 months). Monthly use and disposals in the early and late pandemic periods were compared with the pre-pandemic period. Results: A total of 144114 units of blood and blood components were used. The most commonly used components were erythrocyte concentrate (EC), fresh frozen plasma (FFP) and thrombocyte concentrate (TC), respectively. Their monthly usages in the pre-pandemic period, the early pandemic period and the late pandemic period were 2067.1±147.2, 840±161.3 and 285.4±77.4; 1564.5±287.5, 576.7±146.2 and 261.5±52.6; 1803.5±122.1, 718.6±118.8 and 325.7±52.1; respectively. EC and FFP were used significantly less in the early and late pandemic periods than in the pre-pandemic period (p

Keywords:

Blood components blood destruction, blood usage, COVID-19 pandemic,

PDF

___

1. Cucinotta D, Vanelli M. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020 Mar 19;91(1):157-60. doi: 10.23750/abm.v91i1.9397.
2. Ngo A, Masel D, Cahill C, et al. Blood Banking and Transfusion Medicine Challenges During the COVID-19 Pandemic. Clin Lab Med. 2020; 40:587-601.
3. Shander A, Goobie SM, Warner MA, et al. Essential Role of Patient Blood Management in a Pandemic: A Call for Action. Anesth Analg. 2020;131:74-85.
4. Barrett CL. Primary healthcare practitioners and patient blood management in Africa in the time of coronavirus disease 2019: Safeguarding the blood supply. Afr J Prim Health Care Fam Med. 2020; 12:e1-e3.
5. Barnes LS, Al-Riyami AZ, Ipe TS, et al. COVID-19 and the impact on blood availability and transfusion practices in low- and middle-income countries. Transfusion. 2022;62:336-45. 6. Al-Riyami AZ, Schäfer R, van den Berg K, et al. Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities. Vox Sang. 2021;116:88-98.
7. Stanworth SJ, New HV, Apelseth TO, et al. Effects of the COVID-19 pandemic on supply and use of blood for transfusion. Lancet Haematol. 2020;7(10):e756-e764.
8. Gaur DS, Negi G, Chauhan N, et al. Utilization of blood and components in a tertiary care hospital. Indian J Hematol Blood Transfus. 2009;25:91-95.
9. Koju S , Karmarcharya RM , Makaju R . Pattern of Blood Component Utilization in Tertiary Care Hospital of Central Nepal. Kathmandu Univ Med J (KUMJ). 2019;17(65):20-24.
10. Kurup R, Anderson A, Boston C, et al. A study on blood product usage and wastage at the public hospital, Guyana. BMC Res Notes. 2016;9:307.
11. T.C. Sağlık Bakanlığı. Ulusal Kan ve Kan Ürünleri Rehberi. 1.Baskı. Çesa Basım Hizmetleri, İstanbul. 2011:54
12. Sağlık Hizmetleri Genel Müdürlüğü Sağlıkta kalite. Akreditasyon ve Çalışan Hakları Dairesi Başkanlığı. Sağlıkta Kalite Standartları Gösterge Yönetimi Rehberi Sürüm 2.2. Ankara. 2021: 82
13. Gehrie EA, Frank SM, Goobie SM. Balancing Supply and Demand for Blood during the COVID-19 Pandemic. Anesthesiology. 2020;133:16-18.
14. Kracalik I, Mowla S, Katz L, et al. Impact of the early coronavirus disease 2019 pandemic on blood utilization in the United States: A time-series analysis of data reported to the National Healthcare Safety Network Hemovigilance Module. Transfusion. 2021;61 Suppl 2:S36-S43.
15. Shander A, Goobie SM, Warner MA, et al. Essential Role of Patient Blood Management in a Pandemic: A Call for Action. Anesth Analg. 2020;131:74-85. 16. Baron DM, Franchini M, Goobie SM, et al. Patient blood management during the COVID-19 pandemic: a narrative review. Anaesthesia. 2020;75(8):1105-13.
17. Altıntaş F., Kan ve kan bileşenlerinin genel özellikleri, Yoğun Bakım Derneği Dergisi, Cilt: 3, Sayı 2/2005
18. Barriteau CM, Bochey P, Lindholm PF, Hartman K, Sumugod R, & Ramsey G. Blood transfusion utilization in hospitalized COVID-19 patients. Transfusion, 2020;,60(9), 1919-23. doi: 10.1111/trf.15947.
19. Worrall AP, Kelly C, O'Neill A, Reidy N, O'Doherty M, Griffin L, Quinn J, Thornton P, Fitzpatrick F, Curley GF, Morgan R, Glavey S, McNally C, McConkey S, Murphy P, de Barra E, & Lavin M. Transfusion requirements in patients with COVID-19. Eur J Haematol, 2021; 106(1);132-34. doi: 10.1111/ejh.13521.
20. Dzik S. COVID-19 Convalescent Plasma: Now Is the Time for Better Science. Transfus Med Rev, 34(3), (2020),141-144. doi: 10.1016/j.tmrv.2020.04.002.