İlaçların Neden Olduğu Tat ve Koku Alma Bozuklukları

Koku ve tat almanın yaşamsal fonksiyonlarda önemi büyüktür. İnsanın sosyal yaşantısı ve diyet alışkanlıkları; tat alma ile etkilenmektedir. Ayrıca tat alma duyusu ile koku duyusu yakın bir ilişki içindedir. Bu durumun nedeni koku ve tat duyusunun moleküler düzeyde oldukça karmaşık yapılara sahip olmasıdır. Farklı hastalıkların tedavisinde kullanılan ilaçların çoğunun istenmeyen yan etki olarak tat ve koku duyusunda bozukluğa yol açtığı öne sürülmektedir. Koku ve tat duyularındaki değişiklikler tıbbi olarak gerektiği kadar dikkate alınmamaktadır. Bu durum, hem hastanın tat veya koku alma bozukluğu ile yaşamasına yol açmakta, hem de hastalar yemeklerden hoşnutsuz olmak, keyif alamamak gibi sosyal açılardan da olumsuz etkilenmektedir. Bu derlemenin amacı, ilaçların tat ve koku duyularında neden olduğu etkileri tanımlamak ve bu etkilere neden olabilecek ilaçlar hakkında bilgi sunmaktır.

Drug Induced Taste and Smell Disorders

Odor and taste are important in vital functions. With taste-taking, human social life and dietary habits areaffected all kinds. Besides, odor and taste have quite complex structures at the molecular level. It is claimedthat most of the drugs used in the treatment of different diseases lead to disturbances in taste and smell asan undesirable effect. Changes in smell and taste sensations are not considered as medical necessity. Thissituation does not only cause the patient to live with taste or smell disorder, but also make person to bedisaffected by the food and not to enjoy the social aspects of the person's life. The purpose of this review isto describe the effects of drugs on taste and smell sensations and to provide information about the drugsthat can cause these effects.

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