Yaşlılarda diyet alışkanlıkları ile mitral anüler kalsifikasyon arasında ki ilişki: Çölleşmenin etkisi

Amaç: Bu çalışma önceleri yaşlanma ile alakalı bir olay olarak düşünülen mitral anüler kalsifikasyon oluşumunda diyetin olası rolünü araştırmak için planlandı.Gereç ve Yöntemler:Mitral anüler kalsifikasyonu olan 85 adet ve olmayan 91 adet hasta bu çalışmaya dahil edildi.Tüm hastalara gönüllülük esasına bağlı olarak onaylı ve kapsamlı diyet hikayesiniiçeren, kendi kendilerine cevaplayabildikleri 36 parametrelik anketuygulandı. Olası risk faktörlerinin tek yönlü ve çok yönlü analizleri yapıldı.Bulgular: Mitral anüler kalsifikasyonKırıkkale, Kırsehir, Yozgat, Aksaray, Nevsehir ve Mardin şehirlerinde yaşayan hastalarda belirgin ve bağımsız olarak fazla bulundu( OR= 1, 65, % 95 CI= 1, 25 - 2, 89; p< 0, 001).Bu şehirler İç Anadolu Bölgesinin en fazla kurak, tuzlu ve kalsifik topraklarına sahip şehirleridir ve çölleşme etkisi ile daha tuzlu ve kalsifik olmaktadır. Mitral anüler kalsifikasyon Ordu ve Sinop şehirlerinde yaşayanlarda anlamlı olarak düşüktü( OR= 1, 78, % 95 CI= 1, 02 - 2, 89; p< 0, 01). Bu şehirler Karadeniz Bölgesinin en fazla nem içeren topraklarının bulunduğu şehirlerdir.Mitral anüler kalsifikasyon yaşlıda( OR= 2, 55, % 95 CI= 1, 05 - 3, 93; p=0, 05), kadınlarda(OR= 1, 35, % 95 CI= 1, 05 - 1, 89; p= 0, 04), diyabeti olanlarda( OR= 1, 85, %95 CI= 1, 15 - 3, 21; p< 0, 001) ve statin kullananlarda( OR=3, 01, % 95 CI= 1, 59 - 5, 72; p= 0, 01) belirgin olarak yüksek bulundu. Mitral anüler kalsifikasyonu olan ve olmayan hastaların beslenmelerinde anlamlı bir fark bulunmadı(p= 0, 23).Sonuç:Çalışma sonuçları, mitral anüler kalsifikasyon ile beslenme arasında bir bağlantıgösteremedi ancakliteratürde ilk kez mitral anüler kalsifikasyon ile Anadolu Bölgesi’ nin kurak toprak yapısıarasında bir ilişki olabileceğini düşündürdü.

Anahtar Kelimeler:

Diyet, İklim, Klasifikasyon, mitral anulus, yaşlanma

The relation between mitral annular calcification and dietary habits: Impact of desertification

Aim: This study is planned to find out the potencial role of diet on the formation of mitral annular calcification initially tought to be age-related process.Material and Methods: A total of 85 patients with mitral annular calcification and 91 patients with no- mitral annular calcification were enrolled in this cross- sectional study. A validated, self-administered, comprehensive 36 parameters- diet history questionnaire was applied to all patients on a voluntary basis. Univariate and multivariate analysis were done with possible risk factors.Results: Mitral annular calcification was found significantly and independently higher in patients living in Kırıkkale, Kirsehir, Yozgat, Aksaray, Nevsehir and Mardin( OR= 1. 65, 95% CI= 1. 25 – 2. 89; p< 0, 001). These Central Anatolia cities’ have soils with higher calcium, and higher salt, and lower humidity and soils have becoming more saltier and more calcified with desertification effects. Mitral annular calcification was found significantly and independently lower in patients living in Ordu and Sinop( 0R= 1. 78, 95% CI= 1. 02 – 2. 89; p< 0. 01). These Black Sea Region cities’ have the most humid soil types. Mitral annular calcifications were found significantly higher in aged( OR= 2. 55, 95% CI= 1. 05 – 3. 93; p=0. 05),in women( OR= 1. 35, 95% CI= 1. 05 – 1. 89; p=0. 04), in diabetes( OR= 1. 85, 95% CI= 1.15 – 3. 21; p< 0. 001 )and in statin usage( OR=3. 01, 95% CI= 1. 59 – 5. 72; p= 0. 01). We didn’ t find any correlation between foods and with mitral annular calcification( p= 0. 23).Conclusion: Our study couldn’ t demonstrate any association between mitral annular calcification and with a special food group but made to think for the first time in the literature a possible correlation between mitral annular calcification and with low humidity Cental Anatolia soil types

Keywords:

diet, climate, calcification, mitral annulus, ageing,

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