Synthesis and some reactions of 4-benzoyl-5-phenyl-1-(2,4,6-trichloro phnyl)-1H-pyrazole-3-carboxylic acid

ISSN: 1300-0527
Yayın Aralığı: Yılda 6 Sayı
Yayıncı: TÜBİTAK

Furandione 1 was reacted with 2,4,6-trichlorophenylhydrazine to give the 1 H-pyrazole-3-carboxylic acid 2 together with a new pyridazinone derivative 3. Then 2 was converted into the corresponding ester 5 or amide 6 derivatives, respectively, via reactions of its acid chloride 4 with various alcohols or N-nucleophiles. Nitrile derivative 7 was obtained by dehydration of 6a in a mixture of SOCl2 and DMF. Condensation reactions of 2 with some hydrazines led to the formation of pyrazolo [3,4—d] pyridazinone 8 derivatives.

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