4316

Synthesis and characterization of novel benzovesamicol analogs

Three new racemic vesamicol analogs were successfully prepared in good yields and high purity. All compounds were characterized by both IR and NMR spectroscopy. Compounds (\pm)-5 and (\pm)-6 showed a moderate lipophilicity compared with reference compounds IBVM and DRC140, respectively. However, the lipophilicity of DRC140 and (\pm)-9 showed very similar behaviors.

Anahtar Kelimeler:

Benzovesamicol, ethylenedicysteine, vesicular acetylcholine transporter

Synthesis and characterization of novel benzovesamicol analogs

Three new racemic vesamicol analogs were successfully prepared in good yields and high purity. All compounds were characterized by both IR and NMR spectroscopy. Compounds (\pm)-5 and (\pm)-6 showed a moderate lipophilicity compared with reference compounds IBVM and DRC140, respectively. However, the lipophilicity of DRC140 and (\pm)-9 showed very similar behaviors.

Keywords:

Benzovesamicol, ethylenedicysteine, vesicular acetylcholine transporter,

Turkish Journal of Chemistry-Cover

ISSN: 1300-0527
Yayın Aralığı: Yılda 6 Sayı
Yayıncı: TÜBİTAK

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