Şule AYCAN, Güzin ALPDOĞAN, Sıdıka SUNGUR, Fikriye ELMALI

5597

Polarographic Determination of Fluvoxamine Maleate in Tablets

The differential pulse polarographic (DPP) method was developed for the determination of fluvoxamine maleate (I). At pH = 3. 7, (I) give a peak at - 0. 73 V in aqueous solution. The developed method was applied to the assay of the drug substance in commercial tablet formulations. The results were statistically compared with those obtained by reference methods (HPLC and direct current polarographic method) using t- and F- tests at 95 % confidence level.

Anahtar Kelimeler:

Fluvoxamine maleate, differential pulse polarography, determination, tablets.

Polarographic Determination of Fluvoxamine Maleate in Tablets

The differential pulse polarographic (DPP) method was developed for the determination of fluvoxamine maleate (I). At pH = 3. 7, (I) give a peak at - 0. 73 V in aqueous solution. The developed method was applied to the assay of the drug substance in commercial tablet formulations. The results were statistically compared with those obtained by reference methods (HPLC and direct current polarographic method) using t- and F- tests at 95 % confidence level.

Keywords:

Fluvoxamine maleate, differential pulse polarography, determination, tablets.,

Turkish Journal of Chemistry-Cover

ISSN: 1300-0527
Yayın Aralığı: 6
Yayıncı: TÜBİTAK

Arşiv

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